Results 21 to 30 of about 8,409,985 (265)
IL-31: State of the Art for an Inflammation-Oriented Interleukin. [PDF]
Int J Mol Sci, 2022 Interleukin 31 belongs to the IL-6 superfamily, and it is an itch mediator already studied in several diseases, comprising atopic dermatitis, allergic pathologies, and onco-hematological conditions. This research aims to assess the role of this cytokine in the pathogenesis of these conditions and its potential therapeutic role.
Borgia F +5 more
europepmc +3 more sources
Regulation of myeloid progenitor cell proliferation/survival by IL-31 receptor and IL-31 [PDF]
Experimental Hematology, 2007 Interleukin (IL)-31 is a recently discovered helical cytokine. Its receptor consists of a ligand-specific IL-31 receptor (IL-31R) subunit and a receptor chain that is shared with Oncostatin M (OSM), called OSM-Rbeta. Because OSM-Rbeta-deficient animals have reduced hematopoietic progenitor cells (HPC) and OSM has effects on and is involved in ...
Hal E, Broxmeyer +8 more
openaire +3 more sources
IL‐31 and IL‐31 receptor expression in acute experimental canine atopic dermatitis skin lesions [PDF]
Veterinary Dermatology, 2021 BackgroundTo optimise the interleukin (IL)‐31‐blocking therapy in atopic dermatitis (AD), an understanding of the chronology in the expression of IL‐31 and its receptor (IL‐31RA) is needed.Hypothesis/Objectives(i) To assess the chronological expression of IL‐31 in canine AD skin lesions, (ii) to compare it with serum IL‐31 levels and macroscopic skin ...
Chie Tamamoto‐Mochizuki +1 more
openaire +2 more sources
Structures and biological functions of IL-31 and IL-31 receptors [PDF]
Cytokine & Growth Factor Reviews, 2008 Interleukin-31, produced mainly by activated CD4(+) T cells, is a newly discovered member of the gp130/IL-6 cytokine family. Unlike all the other family members, IL-31 does not engage gp130. Its receptor heterodimer consists of a unique gp130-like receptor chain IL-31RA, and the receptor subunit OSMRbeta that is shared with another family member ...
Qing, Zhang +4 more
openaire +2 more sources
Veterinary Evidence, 2022 PICO question In dogs with atopic skin disease, is lokivetmab more effective than oclacitinib in reducing the Canine Atopic Dermatitis Lesion Index score (or some other recognised scoring system)?
Bonnie Yuan Tone Cheung
doaj +1 more source
Dupilumab for cancer-associated refractory pruritus
Journal of Allergy and Clinical Immunology: Global, 2023 Background: Pruritus can be an intolerable symptom in patients with cancer. Type 2 inflammation, and specifically, the cytokines IL-4, IL-13, and IL-31, play major roles in the itching process.
Aviv Talmon, MD +8 more
doaj +1 more source
, 1990 IL-INFO 31 IL-Info / Institut für Leichte Flächentragwerke (-) IL-Info 1-18 (1969 [6.-8-]) ( - ) IL-Info 1 (1.1970 eng) (-) IL-Info 2 (2. 1971 eng) (-) IL-Info 3 (3. 1971 eng) (-) IL-Info 4 (4. 1971 eng) (-) IL-Info 5
Universität Stuttgart. Institut für Leichte Flächentragwerke
core +5 more sources
Interleukin-31 in serum and cerebrospinal fluid of dogs with syringomyelia
BMC Veterinary Research, 2023 Background Syringomyelia is a spinal cord cavity containing cerebrospinal fluid (CSF)-like fluid. If syringomyelia asymmetrically involves the dorsal horn grey matter of the spinal cord, affected dogs show increased signs of dysesthesia and neuropathic ...
Laura Lemke +6 more
doaj +1 more source
Biomolecules, 2023 Microbiome dysbiosis and cytokine alternations are key features of atopic dermatitis (AD) and psoriasis (PsO), two of the most prevalent and burdensome pruritic skin conditions worldwide.
Laura Bonzano +5 more
doaj +1 more source
Медицинская иммунология, 2021 Atopic dermatitis is one of the most common chronic inflammatory skin diseases caused by both terminal defects in keratinocyte differentiation, and pronounced type 2 immune responses.
M. B. Drozhdina, E. V. Suslova
doaj +1 more source