Results 21 to 30 of about 1,187,146 (230)
IL-33/IL-31 Axis in Osteoporosis. [PDF]
Int J Mol Sci, 2020 The study of the immunoskeletal interface has led to the discovery of numerous cytokines involved in the regulation of bone remodeling, providing valuable information on the pathogenesis of osteoporosis. The role of inflammatory cytokines of the Th1 and Th17 profile in osteoporosis is well known.
De Martinis M +3 more
europepmc +5 more sources
IL-33/IL-31 Axis: A Potential Inflammatory Pathway [PDF]
Mediators of Inflammation, 2018 Cytokines play an important role in the regulation of the immune system (adaptive and innate). Given their importance in proinflammatory processes, cytokines have been used for understanding the pathogenesis and as biomarkers in many diseases.
Eleonora Di Salvo +4 more
doaj +4 more sources
IL-5, IL-31 and systemic immune-inflammation index as biomarkers predicting severity and progression in bullous pemphigoid. [PDF]
Front Med (Lausanne)IntroductionInflammatory mechanisms assume a pivotal role in bullous pemphigoid (BP). IL-31, IL-5, and the systemic immunoinflammatory index (SII) are emerging markers of inflammatory activity, but their associations with BP severity remain unclear. This
Zhang Y +12 more
europepmc +2 more sources
Role of the Pruritic Cytokine IL-31 in Autoimmune Skin Diseases [PDF]
Frontiers in Immunology, 2019 Many autoimmune skin diseases, such as bullous pemphigoid (BP), psoriasis and certain types of chronic urticaria, are associated with intensive pruritus.
Bernhard F. Gibbs +2 more
doaj +4 more sources
Increased serum IL-31 levels in chronic spontaneous urticaria and psoriasis with pruritic symptoms. [PDF]
Heliyon, 2020 Background: Chronic spontaneous urticaria (CSU) is a common pruritic skin condition, the pathogenesis of which remains unclear. Interleukin-31 (IL-31) is a major pruritogenic cytokine that plays a role in inducing pruritus in various skin diseases. Aim.:
Chaowattanapanit S +7 more
europepmc +2 more sources
Regulation of myeloid progenitor cell proliferation/survival by IL-31 receptor and IL-31 [PDF]
Experimental Hematology, 2007 Interleukin (IL)-31 is a recently discovered helical cytokine. Its receptor consists of a ligand-specific IL-31 receptor (IL-31R) subunit and a receptor chain that is shared with Oncostatin M (OSM), called OSM-Rbeta. Because OSM-Rbeta-deficient animals have reduced hematopoietic progenitor cells (HPC) and OSM has effects on and is involved in ...
Hal E, Broxmeyer +8 more
+7 more sources
IL‐31 and IL‐31 receptor expression in acute experimental canine atopic dermatitis skin lesions [PDF]
Veterinary Dermatology, 2021 BackgroundTo optimise the interleukin (IL)‐31‐blocking therapy in atopic dermatitis (AD), an understanding of the chronology in the expression of IL‐31 and its receptor (IL‐31RA) is needed.Hypothesis/Objectives(i) To assess the chronological expression of IL‐31 in canine AD skin lesions, (ii) to compare it with serum IL‐31 levels and macroscopic skin ...
Chie Tamamoto‐Mochizuki +1 more
openaire +2 more sources
Interleukin-31 as a Clinical Target for Pruritus Treatment
Frontiers in Medicine, 2021 In recent years, the published literature has suggested the key involvement of the cytokine interleukin-31 (IL-31) in the symptomatology of pruritus, and both IL-31 and its receptor have become potential therapeutic targets for a range of pruritic ...
Kenji Kabashima, Hiroyuki Irie
doaj +1 more source
Enigmatic Role of IL-31 in the Itch and Inflammation of Vernal Keratoconjunctivitis. [PDF]
Juntendo Med JOkamoto M +4 more
europepmc +3 more sources
Neurobiology of Pain, 2022 To elucidate the mechanisms underlying the antipruritic effect of capsaicin, we investigated how topical application of capsaicin (0.01, 0.1 and 1.0% w/v) affects spontaneous scratching in NC/Nga mice, inerleukin-31 (IL-31) induced in BALB/c mice, and IL-
Iwao Arai +4 more
doaj +1 more source