Results 281 to 290 of about 289,750 (311)
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Journal of Investigative Medicine, 2006
Inflammatory bowel diseases (IBD) are characterized by recurrent inflammation in the gastrointestinal tract. Infiltration of CD4+ lymphocytes and neutrophils is one of the predominant features in IBD. Recently, interleukin (IL)-23 and the downstream T-cell derived cytokine IL-17 have been found to be elevated in IBD patients. However, the role of IL-17
Z. Zhang +4 more
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Inflammatory bowel diseases (IBD) are characterized by recurrent inflammation in the gastrointestinal tract. Infiltration of CD4+ lymphocytes and neutrophils is one of the predominant features in IBD. Recently, interleukin (IL)-23 and the downstream T-cell derived cytokine IL-17 have been found to be elevated in IBD patients. However, the role of IL-17
Z. Zhang +4 more
openaire +1 more source
An Overview of Interleukin-17A and Interleukin-17 Receptor A Structure, Interaction and Signaling
Protein & Peptide Letters, 2015Interleukin-17A (IL-17A) and its receptor (IL-17RA) are prototype members of IL-17 ligand/receptor family firstly identified in CD4+ T cells, which comprises six ligands (IL-17A to IL- 17F) and five receptors (IL-17RA to IL-17RE). IL-17A is predominantly secreted by T helper 17 (Th17) cells, and plays important roles in the development of autoimmune ...
Krstić, Jelena +6 more
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Structural Insights into the Interleukin-17 Family Cytokines and Their Receptors
2019The IL-17 family in humans consists of six distinct cytokines (IL-17A-F) that can interact with five IL-17 receptors (IL-17RA-E). The interaction between these cytokines and their receptors are critical in mediating host defenses while also making major contributions to inflammatory and autoimmune responses as demonstrated through both in vitro and in ...
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Functional characterization of interleukin 17 family members and their receptors in amphioxus
International Journal of Biological MacromoleculesThe interleukin 17 (IL17) cytokine family plays a crucial role in phylogenetically conserved immune defense mechanisms, broadly categorized into two distinct evolutionary lineages: the invertebrate-derived (i-type) and vertebrate-specific (v-type) IL17 homologs.
Haifeng, Li +7 more
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[Expression and significance of interleukin-17 and its receptor in nasal polyps].
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, 2011To detect the expression and distribution of interleukin-17 and interleukin 17 receptor (IL-17R) in nasal polyps and to probe into their significance in the pathology of nasal polyps.The methods of immunohistochemical staining and western blot were used to detect IL-17 and IL-17R in nasal polyps and controls.In nasal polyp tissues, IL-17 expressed ...
Xin, Wang, Zhen, Dong
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Critical Role of Interleukin-17 and Interleukin-17 Receptor Signaling in Tnbs-Induced Colitis
Journal of Investigative Medicine, 2006Z. Zhang +4 more
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Sheng li ke xue jin zhan [Progress in physiology], 2015
Qing-Hai, You +2 more
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Qing-Hai, You +2 more
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Interleukin-22: Immunobiology and Pathology
Annual Review of Immunology, 2015Jarrod A Dudakov, Alan M Hanash
exaly