Results 11 to 20 of about 1,144,647 (289)

Molecular docking and admet properties of anacardium occidentale methanolic nut extract against inflammatory, oxidative and apoptotic markers of diabetes

Journal of Medical Science, 2023
Background. The contemporary antidiabetic drugs have side effects and adverse reactions. This demand to search for less toxic and effective treatments for diabetes from medicinal plants using computational methods.
Ajao Folasade Omobolanle, Iyedupe Marcus Olaoye, Adegbola Raphael Oneosinina, Kalejaiye Noheem Olaolu, Adelusi Temitope Isaac   +4 more
doaj   +1 more source

Soluble interleukin 2 receptors are released from activated human lymphoid cells in vitro.

Journal of Immunology, 1985
With the use of an enzyme-linked immunoabsorbent assay to measure soluble human interleukin 2 receptors (IL 2R), certain human T cell leukemia virus I (HTLV I)-positive T cell lines were found to spontaneously release large quantities of IL 2R into ...
L. Rubin, C. Kurman, M. E. Fritz, W. Biddison, B. Boutin, R. Yarchoan, D. Nelson   +6 more
semanticscholar   +1 more source

Cortisol Dose-Dependently Impairs Migration and Tube-like Formation in a Trophoblast Cell Line and Modulates Inflammatory and Angiogenic Genes

Biomedicines, 2021
Several stimuli can change maternal hormone levels during pregnancy. These changes may affect trophoblastic cells and modulate the development of the embryo and the placental tissue itself.
Talita Guerreiro Rodrigues Húngaro, Marcos F. Gregnani, Thaís Alves-Silva, Florian Herse, Natalia Alenina, Michael Bader, Ronaldo C. Araújo   +6 more
doaj   +1 more source

Low and high affinity cellular receptors for interleukin 2. Implications for the level of Tac antigen

Journal of Experimental Medicine, 1984
Interleukin 2 promotes proliferation of T cells by virtue of its interaction with a high-affinity cell surface receptor. This receptor is a 55,000 mol wt glycoprotein that is also recognized by the murine monoclonal antibody, anti-Tac.
R. Robb, W. Greene, C. M. Rusk
semanticscholar   +1 more source

Soluble Interleukin-2 Receptors in Patients with Advanced Colorectal Carcinoma

The International Journal of Biological Markers, 1996
The levels of soluble interleukin-2 receptors (sIL-2R) were measured in the serum of 52 patients with advanced colorectal carcinoma and compared to CEA and CA 19-9 levels. Twenty-five normal, age and sex-matched individuals served as controls.
N. Pavlidis, C. Nicolaides, E. Bairaktari, J. Kalef-Ezra, A. Athanassiadis, C. Seferiadis, G. Fountzilas   +6 more
doaj   +1 more source

The effects of interleukin-2 on immune response regulation.

Mathematical medicine and biology : a journal of the IMA, 2018
The immune system has many adaptive and dynamic components that are regulated to ensure appropriate, precise and rapid response to a foreign pathogen.
R. Waters, Justin S. A. Perry, Sunpil Han, B. Bielekova, Tomáš Gedeon   +4 more
semanticscholar   +1 more source

Chronic Effects of Subcutaneous Interleukin-2 Therapy on Soluble Interleukin-2 Receptors in Advanced Small Cell Lung Cancer

The International Journal of Biological Markers, 1993
The increase in IL-2 receptor serum levels is one of the most typical changes in immune parameters during IL-2 cancer immunotherapy. To better define the effects of prolonged IL-2 injection on SIL-2R levels, we evaluated 7 advanced small cell lung cancer
S. Viviani, P.M. Salvini, P. Bidoli, E. Camerini, S. Spinazzé, F. Arienti, L. Rivoltini, V. Motta   +7 more
doaj   +1 more source

Essential role of NK cells in IgG therapy for experimental autoimmune encephalomyelitis.

PLoS ONE, 2013
Intravenous immunoglobulin has long been used in treating autoimmune diseases, although mechanisms remain uncertain. Activating Fcγ receptors are receptors of IgG and reported to be essential in intravenous immunoglobulin (IVIG) therapy.
Wai Po Chong, Man To Ling, Yinping Liu, Rachel R Caspi, Wai Man Wong, Wutian Wu, Wenwei Tu, Yu Lung Lau   +7 more
doaj   +1 more source

Characterization of Endocannabinoid System and Interleukin Profiles in Ovine AEC: Cannabinoid Receptors Type-1 and Type-2 as Key Effectors of Pro-Inflammatory Response

Cells, 2020
Amniotic epithelial cells (AEC) have been proposed as promising clinical candidates for regenerative medicine therapies due to their immunomodulatory capacity.
Luana Greco, Valentina Russo, Cinzia Rapino, Clara Di Germanio, Filomena Fezza, Nicola Bernabò, Paolo Berardinelli, Alessia Peserico, Domenico Fazio, Mauro Maccarrone, Mauro Mattioli, Barbara Barboni   +11 more
doaj   +1 more source

Permethrin induced arterial retention of native and oxidized LDL in rats by promoting inflammation, oxidative stress and affecting LDL receptors, and collagen genes

Ecotoxicology and Environmental Safety, 2021
This study is the first to examine the possible mechanism by which long-term exposure to permethrin (PER) can promote arterial retention of proatherogenic lipid and lipoproteins and related vascular dysfunction in rats.
Anouar Feriani, Meriam Tir, Rafik Hachani, Mohamed Salah Allagui, Nizar Tlili, Saber Nahdi, Saleh Alwasel, Abdel Halim Harrath   +7 more
doaj   +1 more source