Results 71 to 80 of about 465,939 (309)

Modulation of Functional Activities of Chicken Heterophils by Recombinant Chicken IFN-γ [PDF]

, 2001
The objective of the present studies was to examine the in vitro effects of recombinant chicken interferon-γ (rChIFN-γ) on shape change, phagocytosis, and the oxidative/nonoxidative killing activities of day-old chicken heterophils.
B. Kaspers, E.J. Pishko, HARMON B.G., K.C. Weining, KLEIN J.B., KOGUT M.H., KOGUT M.H., LEINO L., M.H. Kogut, MERRILL G.A., SETO F., STICKLE J.F., WEINING K.C.   +12 more
core   +1 more source

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

Molecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti, Shingo Inagaki, Tuyen Thuy Bich Ho, Akihiro Seki, Keiko Yoshida, Kosuke Satomura, Yoshio Sakai, Shuichi Kaneko, Taro Yamashita   +8 more
wiley   +1 more source

Plasma levels of immunoinflammatory markers in De Novo coronary atherosclerosis and coronary restenosis postangioplasty

Arquivos Brasileiros de Cardiologia, 2001
OBJECTIVE: To compare circulating plasma levels of immunoinflammatory markers in patients with known de novo coronary artery disease and patients with postangioplasty restenosis.
Alexandre Schaan de Quadros, Jorge Pinto Ribeiro, Waldomiro Carlos Manfroi, Cristiane Leitão, Karen Ordovás, Letícia Weiss, Nadine Clausell   +6 more
doaj   +1 more source

Interleukin-2 signalling is modulated by a labile disulfide bond in the CD132 chain of its receptor [PDF]

Open Biology, 2012
Certain disulfide bonds present in leucocyte membrane proteins are labile and can be reduced in inflammation. This can cause structural changes that result in downstream functional effects, for example, in integrin activation.
Clive Metcalfe, Peter Cresswell, A. Neil Barclay   +2 more
doaj   +1 more source

Effects of intrathecal and intracerebroventricular microinjection of kaempferol on pain: possible mechanisms of action

Research in Pharmaceutical Sciences, 2021
Background and purpose: Kaempferol (KM), a flavonoid, has an anti-inflammatory and anticancer effect and prevents many metabolic diseases. Nonetheless, very few studies have been done on the antinociceptive effects of KM. This research aimed at assessing
Sajjad Jabbari, Maryam Bananej, Mohammad Zarei, Alireza Komaki, Ramin Hajikhani   +4 more
doaj   +1 more source

Cannabinoid signalling in TNF-alpha induced IL-8 release [PDF]

, 2006
Original article can be found at: http://www.sciencedirect.com/science/journal/00142999 Copyright Elsevier B.V.
Baydoun, A. R., Molleman, A., Mormina, M. E., Thakur, S., Whelan, C.J.   +4 more
core   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Neopterin, soluble receptors for interleukin-2 and tumor necrosis factor in viral cirrhosis and alcoholic cirrhosis

Pteridines, 2000
Alcoholic cirrhosis and viral cirrhosis are associated with alterations of immune system function and cytokine production. Our aim was to investigate whether serum concentrations of soluble receptors for interleukin-2 (sIL- 2 R) and tumor necrosis factor
Gonzalez-Calvin Jorge, Tilz Gernot P., Gallego-Rojo Francisco, Torres-Almendros Marina, Widner Bernhard, Diez-Ruiz Antonio, Rico-Irles José, Fuchs Dietmar   +7 more
doaj   +1 more source

Pattern recognition receptors in antifungal immunity [PDF]

, 2014
We thank the Wellcome Trust for funding this study.Peer reviewedPublisher ...
Brown, Gordon D, Hardison, Sarah E, Plato, Anthony   +2 more
core   +2 more sources

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

Molecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric, Annika Auranen, Katrin Kleinmanns, René DePont Christensen, Liv Cecilie Vestrheim Thomsen, Cara Ellen Wogsland, Emmet McCormack, Johanna Mäenpää, Kristine Madsen, Karen Stampe Petersson, Mansoor Raza Mirza, Line Bjørge   +11 more
wiley   +1 more source