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ACCE has a good alleviating effect on AFB1‐induced liver injury, and this alleviating effect is related to the PI3K‐AKT pathway regulated by ACCE and the butyrate metabolism of gut microbiota. ABSTRACT Aflatoxin B1 (AFB1) is a potent hepatotoxin commonly ingested through contaminated food. Abrus cantoniensis Hance, a traditional Chinese medicinal herb,
Hongjie Hu +12 more
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Deciphering the Inflammatory Network in Pediatric Recurrent Tonsillitis: The Role of TRAF6, IRAK1, and miR-146a-5p. [PDF]
Güzel ÖF +3 more
europepmc +1 more source
Therapeutic Opportunities for Macrophage Targeted Nanomedicine in Diabetes Mellitus. [PDF]
Luo J +5 more
europepmc +1 more source
Macrophage peroxisomes at the crossroads of inflammation. [PDF]
Thakkar AV, Lodhi IJ, Thorp EB.
europepmc +1 more source
Gut Microbiota and Metabolites: Orchestrating Depression Pathogenesis Through the Microbiota-Gut-Brain Axis's Neural, Immune, and Metabolic Routes. [PDF]
Dong ZZ +5 more
europepmc +1 more source
IL-17RA/RC blockade modulates the fibrinolytic system and MMP activity in bleomycin-induced pulmonary fibrosis in male mice. [PDF]
Charavu R +3 more
europepmc +1 more source
An IL-21R STAT hypomorph circumvents functional redundancy in germinal centre responses. [PDF]
Jandl C +5 more
europepmc +1 more source
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Breast Disease, 2022
BACKGROUND: Interleukin-21 (IL-21) is produced by various cell types inducing positive and negative effects in immunity against tumors. OBJECTIVE: To investigate the expression of IL-21 by CD4+T and IL-21 receptor (IL-21R) by B lymphocytes isolated from breast-tumor draining lymph nodes (TDLNs).
Sima, Balouchi-Anaraki +6 more
openaire +2 more sources
BACKGROUND: Interleukin-21 (IL-21) is produced by various cell types inducing positive and negative effects in immunity against tumors. OBJECTIVE: To investigate the expression of IL-21 by CD4+T and IL-21 receptor (IL-21R) by B lymphocytes isolated from breast-tumor draining lymph nodes (TDLNs).
Sima, Balouchi-Anaraki +6 more
openaire +2 more sources
Molecular Biology Reports, 2023
We identified a homologue of IL-21R (LcIL-21R) in large yellow croaker (Larimichthys crocea, Lc). Our investigation focused on understanding the molecular structural features and immune function of LcIL-21R.We cloned the LcIL-21R gene from the genome of Larimichthys crocea by RT‒PCR, and the molecular and structural characteristics of LcIL-21R were ...
Hanyu, Wu +5 more
openaire +2 more sources
We identified a homologue of IL-21R (LcIL-21R) in large yellow croaker (Larimichthys crocea, Lc). Our investigation focused on understanding the molecular structural features and immune function of LcIL-21R.We cloned the LcIL-21R gene from the genome of Larimichthys crocea by RT‒PCR, and the molecular and structural characteristics of LcIL-21R were ...
Hanyu, Wu +5 more
openaire +2 more sources

