Results 221 to 230 of about 99,631,586 (306)

Refractory Idiopathic Infantile Pyoderma Gangrenosum Successfully Treated With Infliximab: A Case Report. [PDF]

Case Rep Pediatr
Kurisawa MJ, Nagamori T, Sato M, Ishibazawa E, Tsuda J, Kishibe M, Takahashi S.   +6 more
europepmc   +1 more source

Multi‐Tissue Crosstalk Regulating Meniscus Healing Under Inflammation and Physiological Loading

Advanced Science, EarlyView.
Using a novel Meniscus‐on‐a‐chip (MoC) model integrated with a meniscus‐specific bioreactor, this study investigated the roles of multi‐tissue crosstalk that regulates injury, healing, and degeneration of the meniscus injury under inflammation and pathophysiological loading.
Hun Jin Jeong, Elen Zhu, Min Seo Kang, Ming Wang, Sam Comito, Chang H. Lee   +5 more
wiley   +1 more source

Targeting the IL-23 pathway in inflammatory bowel disease: from cytokine inhibition to oral IL-23 receptor blockade. [PDF]

eGastroenterology
Honap S, Colwill M, Dignass A, Jairath V, Magro F, Danese S, Peyrin-Biroulet L.   +6 more
europepmc   +1 more source

Magnetically Guided Macrophage Immunobots Coordinate Iron‐Metabolic Cascades and Immunogenic Ferroptosis for Tumor Immunotherapy

Advanced Science, EarlyView.
Magnetically guided macrophage immunobots integrate active tumor targeting with immunometabolic therapy. After systemic administration, magnetic actuation enhances immunobot retention and tumor penetration, while LPS‐functionalized FePt microrollers sustain M1‐like polarization through inflammatory and iron‐amplified oxidative signaling and trigger ...
Xirui Zeng, Yingfei Zhang, Chong Wu, Qijia Duan, Mengqi Fan, Kuan Wang, Shirong Cai, Immihan Ceren Yasa   +7 more
wiley   +1 more source

CAR-NK cell immunotherapy: a comprehensive review of engineering platforms, clinical applications in hematological and solid tumors. [PDF]

J Cancer Res Clin Oncol
Awadallah SM, Elmesalamy N, Bahr AR, Atef B, Afroz E, Hill HC.   +5 more
europepmc   +1 more source

Endowing Flexibility of Alveolar Type II Cells to Recapitulate Development From Lung Bud to Alveoli

Advanced Science, EarlyView.
Adult human alveolar type 2 cells are chemically reprogrammed into expandable alveolar progenitor‐like cells that acquire bud tip‐like features during expansion and form organoids that mature into alveolar‐like structures. These organoids model influenza A virus infection and innate immune responses in vitro, while transplanted cells engraft ...
Hongqian Ma, Yuxin Zhang, Lujia Sun, Hong Jiang, Fan Li, Wenming Liu, Shenao Zhou, Mengting Wang, Weijian Huang, Xu Zhou, Caiyang Chen, Qiuqiu Zhang, Xiaoyan Jin, Feihan Yan, Hongping Wu, Yonghong Yin, Xinling Wang, Hexin Yan, Weifeng Yu   +18 more
wiley   +1 more source

The Interplay Between Obesity, Gut Microbiota and Early-onset Colorectal Cancer. [PDF]

In Vivo
Kendong SMA, Razali NN, Bo MS, Sarkawi M, Mokhtar MH, Hamid AA.   +5 more
europepmc   +1 more source

Magneto‐Sono‐Enhanced Nanozyme Catalysis Drives ROS‐Mediated Pathogen Killing and Mitophagy‐Linked Inflammation Control in Bacterial Pneumonia

Advanced Science, EarlyView.
Nebulized BN@NF nanozymes integrate boron nanosheets with Nd‐doped iron phosphide to form a sono‐magneto‐responsive Z‐scheme heterostructure. Under ultrasound and magnetic activation, BN@NF amplifies ROS generation, eradicates bacteria, disrupts biofilms, and reshapes pulmonary inflammation through NF‐κB suppression, mitophagy promotion, and M1‐to‐M2 ...
Xiaofeng Luo, Yundi Wu, Shuai Zhang, Huanran Qu, Shiyang Shao, Jianqiang Chen, Xilong Wu   +6 more
wiley   +1 more source

Inter-Organ Communication in Adipose Tissue Homeostasis: Roles of Skeletal Muscle, Brain, and Heart-Derived Secretory Factors and Signalling Factors. [PDF]

Diabetes Metab Syndr Obes
Zhang H, Yang X, Wu Y, Wang M, Yang Y, Chen X, Wang J, Yan H, Xu Y, Jin Q, Jin Y, Yang M.   +11 more
europepmc   +1 more source