Results 241 to 250 of about 13,667,149 (303)

TAMing the tumor: targeting immune inhibitory receptors on tumor-associated macrophages in pediatric brain tumors - an emerging immunotherapy strategy. [PDF]

J Immunother Cancer
Mooij L, Meesters-Ensing JI, Calkoen FG, van der Lugt J, Meyaard L, Nierkens S, Carvalheiro T.   +6 more
europepmc   +1 more source

The Evolution of IL6-IL6R-JAK-STAT Signaling Pathway in Metazoan. [PDF]

Biology (Basel)
Yu H, Chang R, Wang H, He M, Sun J, Song L.   +5 more
europepmc   +1 more source

12(S)-HETE regulates the expression of IL-6 and IL-10 in cardiomyocytes through two distinct receptors, TXA2R and BLT2. [PDF]

Biochem Biophys Rep
Mori S, Takeda Y, Tomimatsu M, Kametani Y, Yoneda N, Egawa K, Hase H, Tanaka S, Okuda M, Okada Y, Obana M, Fujio Y.   +11 more
europepmc   +1 more source

Cytokine-Family Biomarker Candidates for Small Abdominal Aortic Aneurysm Identified via Integrated mRNA and Protein Expression Profiling. [PDF]

Int J Mol Sci
Stabiszewski P, Zalewski D, Kołodziej P, Ziaja-Sołtys M, Łuszczak J, Szymańska M, Petniak A, Bogucki J, Terlecki P, Stawarz B, Kocki J, Feldo M, Bogucka-Kocka A.   +12 more
europepmc   +1 more source

Cytokine-Driven Hyperinflammation in Long COVID: Mechanisms, Biomarkers, Complement Dysregulation, and Emerging Immunotherapies-A Narrative Review. [PDF]

Health Sci Rep
Obeagu EI.
europepmc   +1 more source

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Interleukin‐4 and the interleukin‐4 receptor in allergic contact dermatitis

Contact Dermatitis, 1998
Cutaneous immune responses involving T helper (TH) type 1 (TH1) and type 2 (TH2) T cells, characterised by secretion of interferon‐γ (Ifn‐γ) and interleukin‐4 (IL‐4), respectively, have both been reported in allergic contact dermatitis (ACD). We used immunohistochemistry to localize expression of IL‐4 in ACD lesions and unaffected skin.
A, Rowe, C B, Bunker
openaire   +2 more sources

Interleukin 4 receptor: signaling mechanisms

Immunology Today, 1994
Achsah Keegan and colleagues consider the signaling mechanisms utilized by the interleukin 4 (IL-4) receptor and review evidence suggesting that these mechanisms can account for the known responses of hematopoietic and non-hematopoietic cells to IL-4. Most of these data have been obtained from analyses of the ability of IL-4 to regulate the growth of ...
A D, Keegan, K, Nelms, L M, Wang, J H, Pierce, W E, Paul   +4 more
openaire   +2 more sources

Interleukin-4 and interleukin-4 receptor polymorphisms in minimal change nephropathy

Clinical Science, 1999
Minimal change nephropathy (MCN) is an important cause of nephrotic syndrome, especially in children, that is strongly associated with atopy and IgE production. The immunogenetics of MCN are poorly understood. Interleukin-4 (IL-4) is the critical cytokine involved in the development of atopy.
Gillespie, KM, Parnham, A, Clark, AGB, Mathieson, PW, Parry, RG   +4 more
openaire   +4 more sources

Interleukin-4 and interleukin-4 receptor polymorphisms and colorectal cancer risk

European Journal of Cancer, 2007
Interleukin-4 (IL-4) and interleukin-4 receptor (IL-4R) modulate inflammation and are associated with the colorectal adenoma-carcinoma progression and the metastatic capacity. IL-4 also causes a dose-dependent reduction of proliferation in colorectal cancer cells.
LANDI, STEFANO, BOTTARI F, GEMIGNANI, FEDERICA, GIOIA PATRICOLA L, GUINO E, OSORIO A, DE OCA J, CAPELLA G, CANZIAN F, MORENO V.   +9 more
openaire   +2 more sources