Results 201 to 210 of about 308,594 (267)

The role of interleukins in peripheral nerve injury and the current status of treatment. [PDF]

Front Immunol
Shen Y, Li M, Jin S, Yu Z, Liu Q, Yao H, Jiang Y, Fu J, Li N.   +8 more
europepmc   +1 more source

Monomeric C-reactive Protein as a Mediator of Chronic Inflammation in Obesity. [PDF]

Cureus
Pentek A, Bacârea A.
europepmc   +1 more source

Thymosin α1 combined with immune checkpoint inhibitors: synergistic remodeling of the tumor immune microenvironment to enhance clinical efficacy and safety. [PDF]

Front Immunol
Guo H, Li R.
europepmc   +1 more source

Targeting IL-1β: a potential strategy for alleviating the immunopathology of aortic aneurysms. [PDF]

Front Immunol
Zhang F, Liao Y, Zhao D, Guo J.
europepmc   +1 more source

Biological Signatures of Inflammation Biomarkers Identified Using Data Reduction Methods in Adult Population: A Scoping Review Protocol. [PDF]

Health Sci Rep
Sánchez-Gordón G, Plans-Beriso E, Barahona-López C, Anta B, Millet O, Fernández-Navarro P, Fernández de Larrea-Baz N, Castelló-Pastor A.   +7 more
europepmc   +1 more source

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Therapeutic Targeting of the Interleukin-6 Receptor

Annual Review of Pharmacology and Toxicology, 2012
Interleukin (IL)-6 is a typical cytokine featuring redundancy and pleiotropic activity. It contributes to host defense against pathogens, but dysregulation of IL-6 production plays a significant pathological role in various autoimmune and inflammatory diseases.
Toshio, Tanaka, Masashi, Narazaki, Tadamitsu, Kishimoto   +2 more
openaire   +2 more sources

Interleukin-6 and interleukin-6 receptor gene expression in pituitary tumors

Journal of Neuro-Oncology, 1994
Interleukin-6 (IL-6) is a multifunctional cytokine which plays a role in the stimulation, inhibition, differentiation, and regulation of cell growth. IL-6 has been shown to act as an autocrine growth factor in several tumors, and is expressed by a variety of tumors. IL-6 also exhibits a regulatory role in the hypothalamo-pituitary axis.
A R, Rezai, A, Rezai, O, Martínez-Maza, M, Vander-Meyden, M H, Weiss   +4 more
openaire   +2 more sources

Serum interleukin-6 and interleukin-6 soluble receptor in Alzheimer's disease

Neuroscience Letters, 1998
Serum levels of interleukin-6 (IL-6) and interleukin-6 soluble receptor (IL-6sR) were measured in 41 patients (23 female and 18 male, mean age 72.5 years) with Alzheimer's disease (AD) and in 32 controls (14 women and 18 men, mean age 69.2 years) using enzyme-linked immunosorbent assays (ELISA).
P, Angelis, S, Scharf, A, Mander, F, Vajda, N, Christophidis   +4 more
openaire   +2 more sources

Fusion Protein of Interleukin-6 and Interleukin-6 Receptor without a Polypeptide Linker

Journal of Bioscience and Bioengineering, 2003
FP6, a novel recombinant fusion protein of interleukin-6 (IL-6) and IL-6 receptor (IL-6R), was prepared in the methylotrophic yeast Pichia pastoris. This protein was a potent activator of a cell surface transducing glycoprotein, gp130 and is a potential therapeutical reagent in the hemopoietic field. A linker is generally thought to be required for two
Kiyoshi, Yasukawa, Shigeo, Tsuchiya, Teiji, Ekida, Hiroshi, Iida, Teruhiko, Ide, Daisuke, Miki, Harutaka, Yagame, Keiichi, Murayama, Takahiko, Ishiguro   +8 more
openaire   +2 more sources