Results 211 to 220 of about 310,876 (265)

Cannabinoid receptor-2 ligand beta-caryophyllene modulates inflammatory responses of bovine peripheral blood mononuclear cells in vitro. [PDF]

Sci Rep
Butenko Y, Shattenstein B, Dos Santos Silva P, Hubner L, Portnick Y, Levin Y, Zachut M.   +6 more
europepmc   +1 more source

Time-Dependent Inflammatory Cytokine Responses in a Human Fetal Membrane Dual-Compartment Model. [PDF]

In Vivo
Sterenczak K, Engist Y, Koepke L, Polei M, Kreutzer HJ, Murua Escobar H, Stubert J.   +6 more
europepmc   +1 more source

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Therapeutic Targeting of the Interleukin-6 Receptor

Annual Review of Pharmacology and Toxicology, 2012
Interleukin (IL)-6 is a typical cytokine featuring redundancy and pleiotropic activity. It contributes to host defense against pathogens, but dysregulation of IL-6 production plays a significant pathological role in various autoimmune and inflammatory diseases.
, Masashi Narazaki, Tadamitsu Kishimoto   +2 more
exaly   +3 more sources

Interleukin-6 and interleukin-6 receptor gene expression in pituitary tumors

Journal of Neuro-Oncology, 1994
Interleukin-6 (IL-6) is a multifunctional cytokine which plays a role in the stimulation, inhibition, differentiation, and regulation of cell growth. IL-6 has been shown to act as an autocrine growth factor in several tumors, and is expressed by a variety of tumors. IL-6 also exhibits a regulatory role in the hypothalamo-pituitary axis.
A R, Rezai, A, Rezai, O, Martínez-Maza, M, Vander-Meyden, M H, Weiss   +4 more
openaire   +2 more sources

Serum interleukin-6 and interleukin-6 soluble receptor in Alzheimer's disease

Neuroscience Letters, 1998
Serum levels of interleukin-6 (IL-6) and interleukin-6 soluble receptor (IL-6sR) were measured in 41 patients (23 female and 18 male, mean age 72.5 years) with Alzheimer's disease (AD) and in 32 controls (14 women and 18 men, mean age 69.2 years) using enzyme-linked immunosorbent assays (ELISA).
P, Angelis, S, Scharf, A, Mander, F, Vajda, N, Christophidis   +4 more
openaire   +2 more sources

Fusion Protein of Interleukin-6 and Interleukin-6 Receptor without a Polypeptide Linker

Journal of Bioscience and Bioengineering, 2003
FP6, a novel recombinant fusion protein of interleukin-6 (IL-6) and IL-6 receptor (IL-6R), was prepared in the methylotrophic yeast Pichia pastoris. This protein was a potent activator of a cell surface transducing glycoprotein, gp130 and is a potential therapeutical reagent in the hemopoietic field. A linker is generally thought to be required for two
Kiyoshi, Yasukawa, Shigeo, Tsuchiya, Teiji, Ekida, Hiroshi, Iida, Teruhiko, Ide, Daisuke, Miki, Harutaka, Yagame, Keiichi, Murayama, Takahiko, Ishiguro   +8 more
openaire   +2 more sources

Interleukin-6 and its receptor in autoimmunity

Journal of Autoimmunity, 1992
Interleukin-6 (IL-6) is a multifunctional cytokine which acts on a wide variety of cells, regulating immune response, acute phase reaction and hematopoiesis. In accordance with its pleiotropic functions, IL-6 is indicated to be involved in the pathogenesis of several diseases including autoimmunities, lymphoid malignancies and inflammations.
openaire   +2 more sources