Results 91 to 100 of about 341,836 (251)
The Isotropic Fractionator as a Tool for Quantitative Analysis in Central Nervous System Diseases [PDF]
, 2016 One major aim in quantitative and translational neuroscience is to achieve a precise and fast neuronal counting method to work on high throughput scale to obtain reliable results.Here we tested the Isotropic Fractionator (IF) method for evaluating ...
Alessandro Vercelli +7 more
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Corticotropin-releasing hormone is a rapid and potent convulsant in the infant rat. [PDF]
, 1991 Corticotropin-releasing hormone (CRH) administered into the cerebral ventricles of rats during the first postnatal week caused a specific and stereotyped behavior sequence: rhythmic chewing and licking (jaw myoclonus) were followed by 'limbic'-type ...
Baram, TZ, Schultz, L
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Structure and function of NMDA-type glutamate receptor subunits
Neurología (English Edition), 2012 Introduction: To review the physiology of the glutamate receptor subunits such as N-methyl-d-aspartate (NMDA). Development: Glutamic acid (Glu) is the major excitatory neurotransmitter in the central nervous system (CNS) which interacts with two types ...
M.E. Flores-Soto +5 more
doaj +1 more source
Marine Drugs, 2008 Domoic acid is a marine biotoxin associated with harmful algal blooms and is the causative agent of amnesic shellfish poisoning in marine animals and humans.
Olga M. Pulido +3 more
doaj
Estructura y función de las subunidades del receptor a glutamato tipo NMDA
Neurología, 2012 Resumen: Introducción: Realizar una revisión de la fisiología de las subunidades del receptor a glutamato tipo N-metil-D-aspartato (NMDA). Desarrollo: El acido glutámico (Glu) es el principal neurotransmisor excitador del sistema nervioso central la ...
M.E. Flores-Soto +5 more
doaj +1 more source
The antiepileptic potential of nucleosides [PDF]
, 2014 Despite newly developed antiepileptic drugs to suppress epileptic symptoms, approximately one third of patients remain drug refractory. Consequently, there is an urgent need to develop more effective therapeutic approaches to treat epilepsy. A great deal
Dobolyi, Á. +3 more
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MoleculesEpilepsy is characterized by abnormal neuronal firing in the brain. Several therapeutic strategies exist for epilepsy; however, several patients remain poorly treated.
Xiaofan Zhang +9 more
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Anxiety-like behavior of prenatally stressed rats is associated with a selective reduction of glutamate release in the ventral hippocampus [PDF]
, 2012 Abnormalities of synaptic transmission and plasticity in the hippocampus represent an integral part of the altered programming triggered by early life stress.
Bouwalerh, H. +10 more
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KCC2 inhibition and neuronal hyperexcitability promote extrinsic apoptosis dependent upon C1q
Frontiers in Molecular NeuroscienceIntroductionThe potassium chloride co-transporter 2 (KCC2) is the principal Cl− extrusion mechanism employed by mature neurons in the central nervous system (CNS) and plays a critical role in determining the efficacy of fast synaptic inhibition mediated ...
Jinglin Ji +5 more
doaj +1 more source
Tiagabine treatment in kainic acid induced cerebellar lesion of dystonia rat model [PDF]
, 2016 Dystonia is a neurological disorder characterized by excessive involuntary muscle contractions that lead to twisting movements. The exaggerated movements have been studied and have implicated basal ganglia as the point of origin. In more recent studies,
Kotchabhakdi, Naiphinich +2 more
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