Role of cytokines in experimental neurodegenerative and neuroinflammatory disorders [PDF]
, 2010 Altered expression of cytokines in response to body injury has diverse actions that can exacerbate, mediate, reduce or inhibit neuronal and myelin damage as well as influence the disease development in a variety of nervous system disorders, such as ...
Zhang, Xing-Mei
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Anti-epileptic properties of terpineol extracted from Myristica fragrans Houtt. essential oil in the epileptic rat model. [PDF]
, 2011 Epilepsy is the manifestation of the disease due to overstimulation of the brain. The common signs of this disease are chronic, episodic and recurrent seizures.
Abdul Rahman, Mohd Amir Asyraf +3 more
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Corticotropin-releasing hormone (CRH) downregulates the function of its receptor (CRF1) and induces CRF1 expression in hippocampal and cortical regions of the immature rat brain. [PDF]
, 2002 In addition to regulating the neuroendocrine stress response, corticotropin-releasing hormone (CRH) has been implicated in both normal and pathological behavioral and cognitive responses to stress. CRH-expressing cells and their target neurons possessing
Baram, Tallie Z +3 more
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An immature mossy fiber innervation of hilar neurons may explain their resistance to kainate-induced cell death in 15-day-old rats. [PDF]
, 1994 Recent studies in adult rodents have shown that mossy fibers, the axons of hippocampal granule cells, sprout into the inner molecular layer of adult rats when hilar cell death occurs following kainate-induced seizure activity.
Navetta, MS, Ribak, CE
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Dopamine receptor stimulation and striatal kainic acid neurotoxicity
Journal of Pharmacy and Pharmacology, 1981 P R, Sanberg, I, Creese
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Regional distribution of the prostaglandin E2 receptor EP1 in the rat brain: accumulation in Purkinje cells of the cerebellum [PDF]
, 2005 Prostaglandin E2 (PGE2), is a major prostanoid produced by the activity of cyclooxygenases (COX) in response to various physiological and pathological stimuli. PGE2 exerts its effects by activating four specific E-type prostanoid receptors (EP1, EP2, EP3
Akundi, Ravi S. +6 more
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Suppression of hippocampal neurogenesis is associated with developmental stage, number of perinatal seizure episodes, and glucocorticosteroid level. [PDF]
, 2003 Seizures increase dentate granule cell proliferation in adult rats but decrease proliferation in young pups. The particular period and number of perinatal seizures required to cause newborn granule cell suppression in development are unknown.
Dashtipour, K +5 more
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Neurotransmitter and receptor changes in kainic acid induced seizures
Pathophysiology, 1994 H. Fukuda, T. Tanaka, Y. Yonemasu
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Synthesis of kainic acid derivatives and their application as kainate receptors probes
, 2019 Kainate receptors play important roles in the central nervous system. However, investigating their role in physiology is hampered by the current lack of tools to study them in dynamic cellular contexts. This thesis describes the synthesis of C4-kainoids and their derivatives, which are designed to serve as chemical probes to study kainate receptors in ...
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