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Vitexin Alleviates Kainic Acid-Induced Seizure Through Inhibiting P2X7R/NLRP3 Signaling Pathway. [PDF]

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Kainic acid and the glutamate receptor

Neuroscience Letters, 1978
Abstract The excitatory effects of microelectrophoretically administered kainic (KAIN) and glutamic (GLUT) acids have been compared on central neurones of the rat in the presence of antagonists of amino acid-induced excitations. Antagonism by both D-α-amino adipic acid (DAA) and glutamic acid diethyl ester (GDEE) of the effects of glutamic acid but ...
Hall, J., Hicks, T., Mclennan, H.
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Retinal benzodiazepine receptors are destroyed by kainic acid lesions

Neuroscience Letters, 1980
[3H]Diazepam binds to preparations of membranes from chicken retina. Two binding sites were detected; a high affinity site (KD, 1.8 nM and Bmax, 0.17 pmol/mg retina protein) and a low affinity site (KD, 132 nM and Bmax, 1.46 pmol/mg retinal protein). GABA stimulated [3H]diazepam binding to these retinal membranes.
M, Willow, I G, Morgan
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Kainic acid stimulates excitatory amino acid neurotransmitter release at presynaptic receptors

Nature, 1982
Kainic acid (KA), a conformationally restricted analogue of glutamic acid, exhibits potent neuroexcitatory1 and neurotoxic properties2. The mechanism of the neurotoxicity of KA, however, seems to be complex and indirect because in many brain areas neuronal vulnerability requires the integrity of excitatory afferents3–6. Nevertheless, neurophysiological
J W, Ferkany, R, Zaczek, J T, Coyle
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The activation of glutamate receptors by kainic acid and domoic acid

Natural Toxins, 1998
The neurotoxins kainic acid and domoic acid are potent agonists at the kainate and alphaamino-5-methyl-3-hydroxyisoxazolone-4-propionate (AMPA) subclasses of ionotropic glutamate receptors. Although it is well established that AMPA receptors mediate fast excitatory synaptic transmission at most excitatory synapses in the central nervous system, the ...
D R, Hampson, J L, Manalo
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