Results 201 to 210 of about 15,962 (236)
Some of the next articles are maybe not open access.
Kainic Acid Modifies μ-Receptor Binding in Young, Adult, and Elderly Rat Brain
Cellular and Molecular Neurobiology, 2002Mu-receptor binding changes were evaluated following the kainic acid (KA)-induced status epilepticus (SE) in young, adult, and elderly animals. Male Wistar rats were used as follows: young rats (15 days old) were treated with KA (7 mg/kg) and sacrificed 72 h (YKA3d) or 35 days (YKA35d) after SE; adult (90 days old) (AKA1d and AKA40d) and elderly rats ...
Claudia, Pérez-Cruz, Luisa, Rocha
openaire +2 more sources
Powerful inhibition of kainic acid seizures by neuropeptide Y via Y5-like receptors
Nature Medicine, 1997Neuropeptide Y (NPY) is widely distributed in interneurons of the central nervous system (CNS), including the hippocampus and cerebral cortex, in concentrations exceeding those of any other known neuropeptides. Sequence data comparing different species show that NPY is highly conserved.
Woldbye, David P. D. +5 more
openaire +2 more sources
Altered expression of NPY-Y1 receptors in kainic acid induced epilepsy in rats
Neuroscience Letters, 1997Kainic acid-induced limbic seizures cause lasting increases in neuropeptide Y (NPY) expression in hippocampal granule cells/mossy fibers. The expression of NPY-Y1 receptors in these neurons were investigated, using in situ hybridization for Y1 mRNA and receptor autoradiography with the Y1-specific ligand [125I][Pro34]PYY.
N, Kofler +3 more
openaire +2 more sources
TNF‐α receptor 1 deficiency enhances kainic acid–induced hippocampal injury in mice
Journal of Neuroscience Research, 2008AbstractThe exact role of TNF‐α in excitotoxic neurodegeneration of the brain is unclear. To address this issue, the kainic acid (KA)–induced hippocampal injury model, a well‐characterized model of human neurodegenerative diseases, was used in TNF‐α receptor 1 (TNFR1)–knockout (TNFR1−/−) mice in the present study.
Ming-Ou, Lu +6 more
openaire +2 more sources
The molecular characterization of a putative kainic acid receptor.
Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada, 1991The purification of a putative kainic acid receptor has been accomplished by the development of a domoic acid affinity column. Domoic acid, immobilized through the carboxylic acid groups, retains the ability to bind kainic acid receptors in solution. The purified receptor from frog brain migrates as a diffuse band centred at a relative molecular weight
D R, Hampson +2 more
openaire +1 more source
Brain Research, 1990
The distributions of N-methyl-D-aspartate (NMDA), alpha-amino-3-hydroxy-S-methyl-4-isoxazole propionic acid (AMPA) and kainic acid (KA) receptors were determined in the human cerebellum using autoradiography. In contrast to the cerebral cortex, where KA receptors have a complementary distribution to NMDA and AMPA receptors, AMPA receptors were ...
K L, Jansen, R L, Faull, M, Dragunow
openaire +2 more sources
The distributions of N-methyl-D-aspartate (NMDA), alpha-amino-3-hydroxy-S-methyl-4-isoxazole propionic acid (AMPA) and kainic acid (KA) receptors were determined in the human cerebellum using autoradiography. In contrast to the cerebral cortex, where KA receptors have a complementary distribution to NMDA and AMPA receptors, AMPA receptors were ...
K L, Jansen, R L, Faull, M, Dragunow
openaire +2 more sources
Autoradiographic localisation of NMDA, quisqualate and kainic acid receptors in human spinal cord
Neuroscience Letters, 1990The phencyclidine (PCP) binding site of the N-methyl-D-aspartate receptor, the kainic acid (KA) receptor and the quisqualate (QA) receptor were visualised, using autoradiography in the human spinal cord and the distributions compared with that of benzodiazepine (BDZ) receptors and substance P (SP).
K L, Jansen +3 more
openaire +2 more sources
Neurotoxicology, 1990
[3H]Quinuclidinyl benzilate (QNB) binding to muscarinic receptors decreased in the rat forebrain after convulsions induced by a single dose of either soman, a potent inhibitor of acetylcholinesterase, or kainic acid, an excitotoxin. A Rosenthal plot revealed that the receptors decreased in number rather than affinity. When the soman-induced convulsions
L, Churchill +4 more
openaire +1 more source
[3H]Quinuclidinyl benzilate (QNB) binding to muscarinic receptors decreased in the rat forebrain after convulsions induced by a single dose of either soman, a potent inhibitor of acetylcholinesterase, or kainic acid, an excitotoxin. A Rosenthal plot revealed that the receptors decreased in number rather than affinity. When the soman-induced convulsions
L, Churchill +4 more
openaire +1 more source
Effect of kainic acid on striatal dopamine receptors
Brain Research, 1980P, Weinreich, P, Seeman
openaire +2 more sources
Kainic acid differentiates GABA receptors from benzodiazepine receptors in the rat cerebellum
Brain Research, 1980Biggio, G. +4 more
openaire +3 more sources