Results 41 to 50 of about 341,836 (251)
Molecules, 2021 Experimental evidence indicates that the activation of ionotropic glutamate receptors plays an important role in neurological disorders’ models such as epilepsy, cerebral ischemia and trauma.
Elisa Landucci +4 more
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Neuropeptide receptors as potential antiepileptic drug targets : focus on the ghrelin axis [PDF]
, 2014 Epilepsy is a very serious neurological disorder which is often underrepresented. Around 50 million individuals worldwide have active epilepsy with recurrent seizures and in spite of the medical advances over the years, 30% of these patients remain as ...
Portelli, Jeanelle
core +1 more source
Journal of Neuroscience, 2001 Delivery of neurotrophic factors to the injured spinal cord has been shown to stimulate neuronal survival and regeneration. This indicates that a lack of sufficient trophic support is one factor contributing to the absence of spontaneous regeneration in ...
J. Widenfalk +4 more
semanticscholar +1 more source
MDMA Increases Excitability in the Dentate Gyrus: Role of 5HT2A Receptor Induced PGE2 Signaling [PDF]
, 2016 MDMA is a widely abused psychostimulant which causes release of serotonin in various forebrain regions. Recently, we reported that MDMA increases extracellular glutamate concentrations in the dentate gyrus, via activation of 5HT2A receptors.
Chiaia, Nicolas +4 more
core +1 more source
Possible Role of N-Methyl-D-Aspartate Glutamate Receptors in The Induction of Acrosome Reaction in Human Sperm [PDF]
Cell JournalObjective: Acrosome reaction is a receptor and Ca2+-dependent process. N-Methyl-D- aspartate (NMDA) glutamatereceptors are expressed in the human sperm and are involved in the Ca2+ influx.
Hamid Reza Momeni +5 more
doaj +1 more source
The tricyclic antidepressant desipramine inhibited the neurotoxic, kainate-induced [Ca] increases in CA1 pyramidal cells in acute hippocampal slices. [PDF]
, 2014 Kainate (KA), used for modelling neurodegenerative diseases, evokes excitotoxicity. However, the precise mechanism of KA-evoked [Ca2+]i increase is unexplored, especially in acute brain slice preparations.
Kiss, János +7 more
core +1 more source
Glutamatergic Activation of Neuronostatin Neurons in the Periventricular Nucleus of the Hypothalamus
Brain Sciences, 2020 Neuronostatin, a newly identified anorexigenic peptide, is present in the central nervous system. We tested the hypothesis that neuronostatin neurons are activated by feeding as a peripheral factor and that the glutamatergic system has regulatory ...
Sema Serter Kocoglu +4 more
doaj +1 more source
Brain Sciences, 2020 Nesfatin-1, identified as an anorexigenic peptide, regulates the energy metabolism by suppressing food intake. The majority of nesfatin-1-synthesizing neurons are concentrated in various hypothalamic nuclei, especially in the supraoptic (SON), arcuate ...
Duygu Gok Yurtseven +3 more
doaj +1 more source
Frontiers in Neuroscience, 2022 Electroacupuncture (EA) stimulates somatic median afferents underlying P5-6 acupoints and modulates parasympathoexcitatory reflex responses through central processing in the brainstem.
Stephanie C. Tjen-A-Looi +6 more
doaj +1 more source
Neuropharmacological targets for drug action in vestibular sensory pathways [PDF]
, 2017 The use of pharmacological agents is often the preferred approach to the management of vestibular dysfunction. In the vestibular sensory pathways, the sensory neuroepithelia are thought to be influenced by a diverse number of neuroactive substances that ...
Jones, Timothy A, Lee, Choongheon
core +3 more sources