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Polycystic Ovary Syndrome Revisited: Novel Insights and Updates. [PDF]
Int J Med SciZhao W +6 more
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Archives of Gynecology and Obstetrics, 2019
Kisspeptins regulate the trophoblast invasion. The disturbance of this process might lead to the development of preeclampsia (PE). Diabetes mellitus (DM) is associated with the high rate of this complication. The main hypothesis was to investigate the placental protein expression of kisspeptin-1 (KISS1) and its receptor (KISS1R) in diabetic ...
R. V. Kapustin +6 more
openaire +2 more sources
Kisspeptins regulate the trophoblast invasion. The disturbance of this process might lead to the development of preeclampsia (PE). Diabetes mellitus (DM) is associated with the high rate of this complication. The main hypothesis was to investigate the placental protein expression of kisspeptin-1 (KISS1) and its receptor (KISS1R) in diabetic ...
R. V. Kapustin +6 more
openaire +2 more sources
Nature Clinical Practice Endocrinology & Metabolism, 2006
Although the hypothalamic secretion of gonadotropin-releasing hormone (GnRH) is the defining hormonal event of puberty, the physiologic mechanisms that drive secretion of GnRH at the time of sexual maturation have been difficult to identify. After puberty is initiated, the factors that modulate the frequency and amplitude of GnRH secretion in rapidly ...
openaire +2 more sources
Although the hypothalamic secretion of gonadotropin-releasing hormone (GnRH) is the defining hormonal event of puberty, the physiologic mechanisms that drive secretion of GnRH at the time of sexual maturation have been difficult to identify. After puberty is initiated, the factors that modulate the frequency and amplitude of GnRH secretion in rapidly ...
openaire +2 more sources
Biology of reproduction, 2009
The KISSPEPTIN-1 receptor (KISS1R) and its ligands (KISSPEPTINS) are implicated in the regulation of the onset of puberty. We report the coding region and genomic structure of the kiss1r gene of a modern teleost, the Senegalese sole (Ss). Ss kiss1r cDNA contained an opening frame of 1137 bp, which results in a predicted 378 amino acid protein ...
Alejandro S, Mechaly +2 more
openaire +1 more source
The KISSPEPTIN-1 receptor (KISS1R) and its ligands (KISSPEPTINS) are implicated in the regulation of the onset of puberty. We report the coding region and genomic structure of the kiss1r gene of a modern teleost, the Senegalese sole (Ss). Ss kiss1r cDNA contained an opening frame of 1137 bp, which results in a predicted 378 amino acid protein ...
Alejandro S, Mechaly +2 more
openaire +1 more source
The kisspeptin-1 receptor antagonist peptide-234 aggravates uremic cardiomyopathy in a rat model
Chronic kidney disease (CKD) is a public health problem that increases the risk of cardiovascular morbidity and mortality worldwide. CKD-associated chronic and often irreversible structural and functional changes of the heart are called uremic cardiomyopathy, characterized by diastolic dysfunction, left ventricular hypertrophy (LVH), and cardiac ...openaire +1 more source
Clinical Potential of Kisspeptin in Reproductive Health
Trends in Molecular Medicine, 2021Layla Thurston, Ali Abbara
exaly
Associations of serum kisspeptin levels with metabolic and reproductive parameters in men
Peptides, 2021Chantacha Sitticharoon +2 more
exaly
There is Kisspeptin – And Then There is Kisspeptin
Trends in Endocrinology and Metabolism, 2015Andrew Wolfe, Mehboob A Hussain
exaly