Results 101 to 110 of about 108,912,939 (192)

Kisspeptin‐10 Prevents the Development of Cerebral Aneurysms by Reducing the Expression of Egr‐1

CNS Neuroscience & Therapeutics
Cerebral aneurysms (CAs) are a prevalent brain condition with poorly understood pathological features. The Kisspeptin‐10 (KP‐10)/G protein‐coupled receptor 54 (GPR54) system is a vital neuroendocrine pathway primarily implicated in the regulation of ...
Hui-Min Yu, Ming-Hong Xie, Xuancong Liufu, Yezi Xu, Lei Chen   +4 more
semanticscholar   +1 more source

Evidence for presence and function of kisspeptin/GnRH system in Leydig cells of horses (Equus caballus)

, 2013
The aim of the present study was to evaluate in the horse Leydig cells (i) the immune-presence of kisspeptin (KiSS) and gonadotropinreleasing hormone (GnRH) and of their cognate receptors (GPR54 and GnRHR, respectively) and (ii) the possible direct ...
C. Vullo, L. Petrucci, VERINI SUPPLIZI, Andrea, M. Bramucci, MARANESI, MARGHERITA, F. Parillo, L. Quassinti, A. Despot, BOITI, Cristiano, M. Zerani   +9 more
core   +1 more source

Functional characterisation of kisspeptin-type signalling in an echinoderm

The neurohormone kisspeptin regulates reproductive maturation and function in mammals by stimulating hypothalamic production and release of gonadotropin releasing hormone.
Islam, T
core   +1 more source

Adult Neurogenesis Is Regulated by the Endocannabinoid and Kisspeptin Systems

International Journal of Molecular Sciences
Neurogenesis is considered the most robust form of plasticity in the adult brain. To better decipher this process, we evaluated the potential crosstalk of Kisspeptin and Endocannabinoid Systems (KPS and ECS, respectively) on hippocampal neurogenesis ...
Marianna Marino, P. Di Pietro, R. D'Auria, M. Lombardi, G. Pastorino, J. Troisi, F. Operto, Albino Carrizzo, C. Vecchione, Andrea Viggiano, R. Meccariello, Antonietta Santoro   +11 more
semanticscholar   +1 more source

Kisspeptin‐54 Restores Blood–Brain Barrier Integrity via GATA‐4 in Ischemic Stroke

Chemical Biology and Drug Design
Ischemic stroke damages the blood–brain barrier (BBB), worsening neuronal injury. Treatments to protect the BBB are limited. We evaluated the neurovascular protective capacity of Kisspeptin‐54 in ischemic stroke using in vivo and in vitro models. In vivo,
Weifeng Shan, Hai-Yan Lan, Yi-Ni Wu, Qiao-Min Xu, Min-Ji You, Ruijun Ma   +5 more
semanticscholar   +1 more source

SUN-157 Unravelling the Regulation of the Kisspeptin Receptor (kiss1r) Through Its Interaction With G Protein-Coupled Estrogen Receptor (gper)

Journal of the Endocrine Society
Disclosure: M.A. Safar: None. V. Jugnarain: None. E. Reiter: None. S.F. Betz: None. A. Abbara: None. W.S. Dhillo: None. A.C. Hanyaloglu: None. The kisspeptin receptor (KISS1R) and G-protein-coupled estrogen receptor (GPER) are both pivotal in the ...
Mohammed A. Safar, V. Jugnarain, Éric Reiter, S. Betz, A. Abbara, W. Dhillo, Aylin C. Hanyaloglu   +6 more
semanticscholar   +1 more source

Kisspeptin-10 inhibits OHSS by suppressing VEGF secretion

, 2017
The aim of the present study was to elucidate the effects of kisspeptin-10 (Kp-10) on ovarian hyperstimulation syndrome (OHSS) and its related mechanism in OHSS rat models, human umbilical vein endothelial cells (HUVECs) and human luteinized granulosa ...
Zi-Jiang Chen, Han Zhao, Weiping Li, Jiansheng Liu, Shigang Zhao, Junyu Zhai, Yanzhi Du   +6 more
core   +1 more source

Expression of GnRH receptor in the canine corpus luteum, and luteal function following deslorelin acetate‐induced puberty delay

Reproduction in domestic animals = Zuchthygiene, 2017
D. Kaya, A. Gram, M. Kowalewski, S. Schäfer-Somi, M. Kuru, A. Boos, S. Aslan   +6 more
semanticscholar   +1 more source

Why kisspeptin is such important for reproduction?

, 2011
Recently discovered neuropeptide called kisspeptin is thought to be an essential gatekeeper in control of reproduction. Kisspeptin, the product of KiSS-1 gene and its G protein-coupled receptor GPR54 play a master role in the puberty period and fertility.
GENAZZANI, ANDREA, Podfigurna Stopa A, Meczekalski B   +2 more
core  

Seminal Plasma Kisspeptin‐1 and Kisspeptin‐54 Levels Are Associated With Semen Parameters and Oxidative Stress in Male Infertility

Objective Kisspeptin‐1 and Kisspeptin‐54 are key regulators of the hypothalamic–pituitary–gonadal axis and may play a role in male reproductive function.
Oya Korkmaz, Pelin Macit, Seda Karabulut, Korkmaz, Oya, Macit, Pelin, Karabulut, Seda   +5 more
core   +1 more source