Results 161 to 170 of about 108,912,939 (192)

Evaluation of candidate point mutation of Kisspeptin 1 gene associated with litter size in Indian Goat breeds and its effect on transcription factor binding sites.

Domestic Animal Endocrinology, 2021
Kisspeptin gene (Kiss1) has a significant role in reproductive processes in mammals. However, only little information is available about the association of Kiss1 gene with litter size in Indian goat breeds.
Vikram Jeet, A. Magotra, Y. Bangar, S. Kumar, A. Garg, A. S. Yadav, P. Bahurupi   +6 more
semanticscholar   +1 more source

Studies on 3D Structure Prediction and Binding Modes of Kisspeptin Receptor 1 Complexed with Kisspeptin 1 using Molecular Docking Approach

International Journal of Pure & Applied Bioscience, 2019
R. Kumari
openaire   +2 more sources

Kisspeptin stimulates sheep ovarian follicular development in vitro through homologous receptors.

Zygote (Cambridge. Print), 2023
The present study was conducted to elucidate (1) the influence of kisspeptin (KP) on the in vitro development of preantral follicles (PFs) and (2) evolution of KP receptor gene (KISS1R) expression during ovarian follicular development in sheep ...
B. D. Sri, S. H. Lekha, K. Reddy, Deepa Pathipati, B. R. Naik, P. Jagapathy Ramayya, K. Veera Bramhaiah, L. S. S. Varaprasad Reddy, A. S. Siva Kumar   +8 more
semanticscholar   +1 more source

KISS1/KISS1R and Breast Cancer: Metastasis Promoter

Seminars in Reproductive Medicine, 2019
Kisspeptins (KPs), peptide products of the kisspeptin-1 (KISS1) gene, are the endogenous ligands for the KISS1 receptor, KISS1R, which is a G protein-coupled receptor. In many human tumors, KISS1 functions as a metastasis-suppressor gene and KISS1/KISS1R
Stephania Guzman, M. Brackstone, F. Wondisford, A. Babwah, Moshmi Bhattacharya   +4 more
semanticscholar   +1 more source

Evidence for human kisspeptin receptor homo-oligomerization and its functional relevance.

Journal of Molecular Endocrinology
The signaling of kisspeptin-1 through the kisspeptin-1 receptor (KISS1R) is central to mammalian reproduction. Naturally occurring heterozygous KISS1R mutations and Kiss1r+/- knockout mice are less affected than homozygous counterparts ; suggesting that,
Aishwarya P. Chakraborty, Vidhi B Rathod, Shobha Sonawane, Shital R Bhanarkar, Bhakti R. Pathak, Antara A. Banerjee   +5 more
semanticscholar   +1 more source

Participation of kisspeptin, progesterone, and GnRH receptors on lordosis behavior induced by kisspeptin.

Physiology and Behavior
The neuropeptide kisspeptin (Kiss) is crucial in regulating the hypothalamic-pituitary-gonadal axis. It is produced by two main groups of neurons in the hypothalamus: the rostral periventricular region around the third ventricle and the arcuate nucleus ...
Oscar González-Flores, R. Domínguez-Ordóñez, R. Delgado-Macuil, J. L. Tlachi-López, Ailyn Luna-Hernández, O. Montes-Narváez, James G. Pfaus, M. García-Juárez   +7 more
semanticscholar   +1 more source

Expression of progesterone receptor, estrogen receptors α and β, and kisspeptin in the hypothalamus during perinatal development of gonad-lacking steroidogenic factor-1 knockout mice.

Brain Research, 2019
Gonadal hormones contribute to brain sexual differentiation. We analyzed expression of progesterone receptor (PR), estrogen receptor-α (ERα), ERβ, and kisspeptin, in the preoptic area (POA) and/or the arcuate nucleus (ARC), in gonad-lacking steroidogenic
Y. Ikeda, Tomoko Kato-Inui, A. Tagami, M. Maekawa   +3 more
semanticscholar   +1 more source

Identification of two isoforms of the Kisspeptin-1 receptor (kiss1r) generated by alternative splicing in a modern teleost, the Senegalese sole (Solea senegalensis).

Biology of reproduction, 2009
The KISSPEPTIN-1 receptor (KISS1R) and its ligands (KISSPEPTINS) are implicated in the regulation of the onset of puberty. We report the coding region and genomic structure of the kiss1r gene of a modern teleost, the Senegalese sole (Ss). Ss kiss1r cDNA contained an opening frame of 1137 bp, which results in a predicted 378 amino acid protein ...
Alejandro S, Mechaly, Jordi, Viñas, Francesc, Piferrer   +2 more
openaire   +1 more source

Kisspeptin isoforms: versatile players in reproduction and beyond.

Journal of Molecular Endocrinology
Kisspeptin and its cognate G-protein-coupled receptor (GPCR), the Kisspeptin-1 receptor, KISS-1R, are central to mammalian reproduction, regulating the hypothalamic-pituitary-gonadal (HPG) axis.
Aishwarya P. Chakraborty, Antara A. Banerjee   +1 more
semanticscholar   +1 more source

The kisspeptin-1 receptor antagonist peptide-234 aggravates uremic cardiomyopathy in a rat model

Chronic kidney disease (CKD) is a public health problem that increases the risk of cardiovascular morbidity and mortality worldwide. CKD-associated chronic and often irreversible structural and functional changes of the heart are called uremic cardiomyopathy, characterized by diastolic dysfunction, left ventricular hypertrophy (LVH), and cardiac ...
openaire   +1 more source