Results 41 to 50 of about 3,979 (188)
Yingna He, Linhua Zhang, Cunxian SongKey Laboratory of Biomedical Material of Tianjin, Institute of Biomedical Engineering, Peking Union Medical College and Chinese Academy of Medical Sciences, Tianjin, ChinaAbstract: A sterically stabilized ...
Yingna He, Linhua Zhang, Cunxian Song
doaj
The presence of LHRH‐like receptors in Dunning R3327H prostate tumors
Quantitative analyses of LH‐RH‐like membrane receptors were performed in five tumors from the transplantable Dunning R3372H rat prostatic adenocarcinoma. The binding of D‐Trp6‐LH‐RH, an agonist of LH‐RH, was observed in all 5 tumors. The antagonist [Ac‐Dp‐Cl‐Phe1,2,D‐Trp3,D‐Lys6,D‐Ala10]‐LH‐RH was bound to 4 tumors.
Hierowski, Marion T. +3 more
openaire +2 more sources
Cyclodextrin‐Amino Acid Conjugates: Synthesis and Pharmaceutical Applications
Cyclodextrins (CDs) can be combined with amino acids via host‐guest complexation or by covalent conjugation through various synthetic routes. The chemical modifications introduce structural versatility, multifunctionality, and biocompatibility, which are essential characteristics for designing effective, next‐generation pharmaceutical formulations ...
Andrea Cesari +2 more
wiley +1 more source
Muscarine and t-LHRH suppress M-current by activating an IAP- insensitive G-protein [PDF]
The control of M-current by muscarinic ACh receptors and luteinizing hormone releasing hormone (LHRH) receptors was studied in dialyzed frog sympathetic ganglion neurons.
P Pfaffinger
core +1 more source
Yingna He,1 Linhua Zhang,2 Dunwan Zhu,2 Cunxian Song2 1Laboratory of Chinese Medicine Pharmacology, College of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, People’s Republic of China; 2Key Laboratory of Biomedical Material ...
He Y, Zhang L, Zhu D, Song C
doaj
Small Molecule‐Based Conditional Gene Regulation: Advances and Applications
The precise, temporal, and reversible control of gene expression using small molecule ligands is crucial for understanding complex cellular functions and is rapidly advancing the field of synthetic biology. Small molecule‐mediated conditional gene regulation has widespread applications, including bio‐manufacturing, cellular reprogramming, gene therapy,
Mohd Afaque Ansari +3 more
wiley +1 more source
Expression of Human Type-I LHRH Receptors and Type-I LHRH in Human Benign Prostatic Hyperplasia [PDF]
Az idősebb férfiak leggyakoribb urológiai betegsége a benignus prosztata hiperplázia (BPH). A BPH rizikó faktorai a prosztata volumen, az életkor és a PSA-szint.
Rózsa, Bernadett
core
Reproductive Cancer Cell Targeting of Pt-Mal-LHRH [PDF]
Triple-negative breast cancer (TNBC) and ovarian cancer are devastating diseases with high mortality rates. Platinum based chemotherapy drugs are common treatment options, including carboplatin and cisplatin, but they often result in severe side effects,
Nienaber, Emma
core
ABSTRACT Background Emerging evidence indicates significantly poorer overall survival for men with metastatic prostate cancer in resource‐limited settings than in high‐income countries. However, there is less understanding of the overall survival of non‐metastatic disease, which could inform early treatment strategies.
Raylton P. Chikwati +9 more
wiley +1 more source
Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery
This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem +9 more
wiley +1 more source

