Results 41 to 50 of about 3,796 (149)
International Journal of Nanomedicine, 2014 Yingna He,1 Linhua Zhang,2 Dunwan Zhu,2 Cunxian Song2 1Laboratory of Chinese Medicine Pharmacology, College of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, People’s Republic of China; 2Key Laboratory of Biomedical Material ...
He Y, Zhang L, Zhu D, Song C
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Castration Resistance Accelerates Prostate Cancer Kinetics
The Prostate, Volume 86, Issue 9, Page 1021-1027, June 15, 2026.ABSTRACT Background Prostate cancer can be an indolent disease with which patients can live for many years. Thus, an understanding of how therapy and its ensuing resistance affect prostate cancer kinetics may guide efforts to determine optimal timing of therapy initiation.
Sheila Jonnatan +10 more
wiley +1 more source
Exploring Lived Experiences of Men Diagnosed With Prostate Cancer in Oman: A Qualitative Study
Health Expectations, Volume 29, Issue 3, June 2026.ABSTRACT Background Life after prostate cancer treatment may extend across decades; however, qualitative evidence describing how men in Oman navigate treatment sequelae, disclosure, family involvement, and religious coping remains limited. This study explored the lived experiences of Omani men who had completed primary therapy for prostate cancer ...
Khalood Al‐Abri +6 more
wiley +1 more source
The Prostate, Volume 86, Issue 6, Page 697-709, May 2026.ABSTRACT Background Combined inhibition of AKT and the androgen receptor (AR) might be more efficacious than AR inhibition alone in biochemical recurrence (BCR) of prostate cancer (PC) by additive effects on the two effector pathways. Patients and Methods E2809 assigned 108 high‐risk BCR patients (1:1, arm‐A: arm‐B) to two phases with 4‐week cycles ...
Anna C. Ferrari +12 more
wiley +1 more source
The Prostate, Volume 86, Issue 6, Page 727-731, May 2026.ABSTRACT Background Methyl Methanesulfonate‐Sensitivity Protein 22‐Like (MMS22L) plays a key role in homology‐directed DNA repair, and experimental models have shown that its loss confers sensitivity to Poly (ADP‐ribose) polymerase inhibitors (PARPi).
Mayuko Kanayama +12 more
wiley +1 more source
International Journal of Urology, Volume 33, Issue 5, May 2026.ABSTRACT Purpose There are few reports investigating urodynamic changes after radiotherapy and hormonal therapy (HT) for prostate cancer. We prospectively evaluated differences in bladder outlet obstruction (BOO) using pressure‐flow studies (PFS) before and after HT and radiotherapy in patients with high‐risk localized or locally advanced prostate ...
Yuki Kyoda +7 more
wiley +1 more source
Cancer Medicine, Volume 15, Issue 4, April 2026.ABSTRACT Objectives Local therapy for metastatic castration‐sensitive prostate cancer (mCSPC) remains controversial. This study aimed to assess the feasibility, safety, and oncologic outcomes of cytoreductive radical prostatectomy (cRP) in patients with synchronous mCSPC, with a particular focus on pathological findings.
Kento Morozumi +8 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 4, April 2026.ABSTRACT Although prostate cancer is among the most common malignant tumors in men, brain metastases from prostatic cancer are infrequent. Brain dissemination is especially rare with the most frequent histological type of prostatic adenocarcinoma. We present a case of a cystic‐hemorrhagic cerebellar metastasis with a solid enhancing component in a ...
Mia Smoljan Basuga +5 more
wiley +1 more source
Cyclodextrin‐Amino Acid Conjugates: Synthesis and Pharmaceutical Applications
ChemistryEurope, Volume 4, Issue 4, April 2026.Cyclodextrins (CDs) can be combined with amino acids via host‐guest complexation or by covalent conjugation through various synthetic routes. The chemical modifications introduce structural versatility, multifunctionality, and biocompatibility, which are essential characteristics for designing effective, next‐generation pharmaceutical formulations ...
Andrea Cesari +2 more
wiley +1 more source
Small Molecule‐Based Conditional Gene Regulation: Advances and Applications
Chemistry–Methods, Volume 6, Issue 4, April 2026.The precise, temporal, and reversible control of gene expression using small molecule ligands is crucial for understanding complex cellular functions and is rapidly advancing the field of synthetic biology. Small molecule‐mediated conditional gene regulation has widespread applications, including bio‐manufacturing, cellular reprogramming, gene therapy,
Mohd Afaque Ansari +3 more
wiley +1 more source