Effects of long-term treatment with the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl and the LHRH antagonist Cetrorelix on the levels of pituitary LHRH receptors and their mRNA expression in rats [PDF]
The effects of depot formulations of the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl (25 μg/day) for 30 days or LHRH antagonist Cetrorelix pamoate (100 μg/day) for 30 days and daily injections of 100 μg of Decapeptyl for 10 days on ...
Horvath, Judit E +5 more
core +1 more source
A Retrospective Study on the Impact of Primary Aldosteronism in Pregnancy (H.A.P.P.I. Study Group)
ABSTRACT Objective Primary aldosteronism (PA) is a common cause of hypertension in young women. However, there is a paucity of data regarding its impact during pregnancy. The primary objective of this study was to describe the occurrence of hypertensive disorders of pregnancy (HDP) in PA.
Diana Oprea +7 more
wiley +1 more source
Targeted chemotherapy of endometrial, ovarian and breast cancers with cytotoxic analogs of luteinizing hormone-releasing hormone (LHRH) [PDF]
Receptors luteinizing hormone-releasing hormone (LHRH) are expressed in about 80 % of human endometrial and ovarian cancers and account for more than 50 % of breast cancers including triple negative breast cancers.
Seitz, Sebastian +15 more
core +1 more source
WITHDRAWN: The use of nanoparticles in LHRH receptor targeted therapy for cancer
While chemotherapy remains the most effective means of treatment for cancer patients, it has become apparent that more efficient modalities are needed. As an alternative to current methods, which can often be toxic to healthy cells and tissues, we discuss "targeted therapy" as an alternate to conventional chemotherapy.
Sarah E, Norberto, Sham S, Kakar
openaire +2 more sources
Lifestyle implications of the paradox and management of oxidative stress in sperm
Abstract figure legend Lifestyle factors influencing male fertility. Schematic overview of lifestyle factors with beneficial (left) and detrimental (right) effects on male fertility. A balanced diet, regular moderate physical activity and stress management strategies support sperm function and redox homeostasis.
Giuseppe T. Patané +6 more
wiley +1 more source
GnRH receptor activation competes at a low level with growth signaling in stably transfected human breast cell lines [PDF]
Breakthrough Breast CancerBackground: Gonadotrophin releasing hormone (GnRH) analogs lower estrogen levels in pre-menopausal breast cancer patients. GnRH receptor (GnRH-R) activation also directly inhibits the growth of certain cells.
Sims Andrew H +27 more
core +1 more source
Adrenal luteinizing hormone releasing hormone receptors. [PDF]
Paraffin sections of mouse adrenals processed with antiserum to luteinizing hormone-releasing hormone (LHRH) in the unlabeled antibody enzyme method reveal moderate staining in the cytoplasm of cells of zona fasciculata and reticularis.
L A Bernardo +3 more
core +1 more source
ENDOCRINE MECHANISMS OF PUBERTY IN HEIFERS (ESTRADIOL FEEDBACK, LUTEINIZING HORMONE, RECEPTORS, NUTRITION, LHRH, RELEASING HORMONE) [PDF]
Endocrine mechanisms which control puberty in heifers were evaluated in two experiments. Prepubertal changes in cytosolic estradiol receptors (preoptic area, hypothalamus and pituitary), pituitary receptors for LHRH, hypothalamic LHRH content, ovarian ...
DAY, MICHAEL L
core
Androgen-dependent prostatic tumors: biosynthesis and possible actions of LHRH [PDF]
Testosterone (T) is the major exogenous stimulus for the growth of prostatic carcinoma. It is believed that the proliferative action of T may be mediated by locally expressed growth modulatory factors.
P. Limonta +4 more
core +1 more source
Localization of receptors for luteinizing hormone-releasing hormone in pancreatic and mammary cancer cells [PDF]
Previous work showed that hamster and human pancreatic tumors but not normal pancreata exhibit low-affinity cell-membrane receptors for luteinizing hormone-releasing hormone (LHRH).
Timar, J +8 more
core +1 more source

