P2Y₂ Nucleotide Receptors Expressed Heterologously in Sympathetic Neurons Inhibit Both N-Type Ca²⁺ and M-Type K⁺ Currents [PDF]
, 1998 The P2Y₂ receptor is a uridine/adenosine triphosphate (UTP/ATP)-sensitive G-protein-linked nucleotide receptor that previously has been reported to stimulate the phosphoinositide signaling pathway.
Webb, TE +3 more
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Search for novel therapies for triple negative breast cancers (TNBC): analogs of luteinizing hormone-releasing hormone (LHRH) and growth hormone-releasing hormone (GHRH) [PDF]
, 2012 Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype that is clinically negative for the expression of estrogen and progesterone receptors (ER/PR) and human epidermal growth factor receptor-2 (HER2). Patients with TNBC have a worse
Block, Norman L +7 more
core +1 more source
Cloning and characterisation of gonadotropin-releasing hormone (GnRH) receptors in the cichlid (Haplochromis burtoni) and the zebrafish (Danio rerio) [PDF]
, 2003 Bibliography: leaves 75-89.The identification of multiple forms of gonadotropin-releasing hormone (GnRH) in a single species is becoming a common occurrence.
Morley, Michelle Gaye
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Luteinizing hormone releasing hormone-RNase A conjugates specifically inhibit the proliferation of LHRH-receptor-positive human prostate and breast tumor cells [PDF]
, 2019 Human prostate and breast tumor cells produce luteinizing hormone-releasing hormone (LHRH) receptors on their cell surface even when they have lost dependency on sex steroid hormones for growth.
Chae, CB, Gho, YS
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Treatment of Precocious Puberty with LHRH Agonists A Pilot Study of the Efficiency of Periodic Administration of a Delayed-Release Preparation of D-Trp6-LHRH [PDF]
A better understanding of the paradoxical inhibitory effects of LHRH agonists has led to the discovery of new therapeutic agents, thanks largely to the experimental studies of Knobil’s group (Belchetz et al., 1978).
Job, Jean-Claude +6 more
core +1 more source
Receptor activation in GNRH receptors [PDF]
, 2000 Includes bibliographical ...
Ott, Thomas Ruthard
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Luteinizing hormon-releasing hormon (LHRH) receptor based new possible targeted therapy for human uveal melanoma [PDF]
, 2019 Az elmúlt évtizedekben az uveális melanomás (UM) betegek átlagos túlélése az alkalmazott terápiák ellenére semmit sem változott. Metasztázis esetén a betegek átlagos túlélése nem éri el az egy évet sem, ráadásul a primer tumor kezelésétől függetlenül az ...
Oláh, Gábor
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LHRH-Receptor Mediated Targeting of Cancer Cells Using Curcumin Nano-micelle Formulation [PDF]
, 2018 Breast cancer is the most common malignancy and the second leading cause of cancer-related death among Australian women despite existing progress in the development of novel therapeutic strategies.
Ahmad, Nadeem
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Antiproliferative effects of luteinizing hormone-releasing hormone (LHRH) agonists on human androgen-independent prostate cancer cell line DU 145: evidence for an autocrine-inhibitory LHRH loop [PDF]
, 1994 The therapeutic options for the treatment of androgen-independent prostatic cancers are rather limited; this is mainly because our understanding of the local mechanisms involved in the control of androgen-independent proliferation of the tumor is still ...
P. Limonta +5 more
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Luteinizing Hormone-Releasing Hormone (LHRH)-Targeted Treatment in Ovarian Cancer. [PDF]
Int J Mol SciNayak P +5 more
europepmc +1 more source