Results 21 to 30 of about 122,271 (244)

Drosophila Lipophorin Receptors Recruit the Lipoprotein LTP to the Plasma Membrane to Mediate Lipid Uptake. [PDF]

PLoS Genetics, 2015
Lipophorin, the main Drosophila lipoprotein, circulates in the hemolymph transporting lipids between organs following routes that must adapt to changing physiological requirements.
Míriam Rodríguez-Vázquez, David Vaquero, Esmeralda Parra-Peralbo, John E Mejía-Morales, Joaquim Culi   +4 more
doaj   +1 more source

Is the atherosclerotic phenotype of preeclamptic placentas due to altered lipoprotein concentrations and placental lipoprotein receptors? Role of a small-for-gestational-age phenotype

Journal of Lipid Research, 2013
Atherosis of spiral arteries in uteroplacental beds from preeclamptic women resemble those of atherosclerosis, characterized by increased plasma lipids and lipoproteins. We hypothesized that: 1) lipoprotein receptors/transporters in the placenta would be
Marta R. Hentschke, Carlos E. Poli-de-Figueiredo, Bartira E. Pinheiro da Costa, Lesia O. Kurlak, Paula J. Williams, Hiten D. Mistry   +5 more
doaj   +1 more source

Role of lipoprotein apheresis in the management of familial hypercholesterolemia

Global Journal of Transfusion Medicine, 2021
Familial Hypercholesterolemia (FH) is an autosomal dominant disorder due to a congenital absence of low-density lipoprotein receptor (LDL-R) that transports cholesterol-carrying lipoprotein particles into cells.
Shamanna Seshadri Iyengar, Ambuja Kantharaj, Chandrashekar Shivaram, D S Hemantha Kumara, Roopa Murgod, G Shreedhara   +5 more
doaj   +1 more source

Low-Density Lipoprotein Receptors

Nederlands tijdschrift voor geneeskunde, 1991
The origins of the receptor theory are based on the work of Paul Ehrlich (1854–1915) and John Newport Langley (1852–1925) (Parascandola 1981), who were the first to postulate that specific cellular reactions to drugs must be based on so-called receptive substances.
Niendorf, A., Beisiegel, Ulrike, Seifert, G.   +2 more
openaire   +5 more sources

Peroxisome Proliferator Activated Receptors and Lipoprotein Metabolism

PPAR Research, 2008
Plasma lipoproteins are responsible for carrying triglycerides and cholesterol in the blood and ensuring their delivery to target organs. Regulation of lipoprotein metabolism takes place at numerous levels including via changes in gene transcription.
Sander Kersten
doaj   +1 more source

Effect of pregnancy and lactation on lipoprotein and cholesterol metabolism in the rat

Journal of Lipid Research, 1998
Origins of hyperlipidemia and cholestasis that occur during pregnancy were investigated by examining expression of key elements related to plasma and hepatic cholesterol metabolism during pregnancy, lactation, and post-lactation in the rat model.
Jeffery L. Smith, Steven R. Lear, Trudy M. Forte, William Ko, Mara Massimi, Sandra K. Erickson   +5 more
doaj   +1 more source

LRP-1 and LRP-2 receptors function in the membrane neuron. Trafficking mechanisms and proteolytic processing in Alzheimer’s disease

Frontiers in Physiology, 2012
Low density lipoprotein receptor-related protein (LRP) belongs to the low-density lipoprotein receptor family, generally recognized as cell surface endocytic receptors, which bind and internalize extracellular ligands for degradation in lysosomes ...
Carlos eSpuch, Saida eOrtolano, Carmen eNavarro   +2 more
doaj   +1 more source

High density lipoprotein receptors, binding proteins, and ligands

Journal of Lipid Research, 1999
Several HDL binding proteins, quite disparate in structure, have recently been cloned and their role in HDL metabolism is currently being assessed. High density lipoprotein binding protein, HBP (vigilin), which lacks a transmembrane domain is responsive ...
Noel H. Fidge
doaj   +1 more source

New horizons for lipoprotein receptors: communication by β-propellers

Journal of Lipid Research, 2013
The lipoprotein receptor (LR) family constitutes a large group of structurally closely related receptors with broad ligand-binding specificity. Traditionally, ligand binding to LRs has been anticipated to involve merely the complement type repeat (CR ...
Olav M. Andersen, Robert Dagil, Birthe B. Kragelund   +2 more
doaj   +1 more source

Cell-associated heparin-like molecules modulate the ability of LDL to regulate PCSK9 uptake[S]

Journal of Lipid Research, 2019
Proprotein convertase subtilisin/kexin type 9 (PCSK9) targets the LDL receptor (LDLR) for degradation, increasing plasma LDL and, consequently, cardiovascular risk.
Adri M. Galvan, John S. Chorba
doaj   +1 more source