Results 1 to 10 of about 783,324 (285)
Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus. [PDF]
PLoS Pathogens, 2016 Scavenger receptor class B type 1 (SR-B1) and low-density lipoprotein receptor (LDLR) are known to be involved in entry of hepatitis C virus (HCV), but their precise roles and their interplay are not fully understood. In this study, deficiency of both SR-
Satomi Yamamoto +14 more
doaj +5 more sources
Interdependent Impact of Lipoprotein Receptors and Lipid-Lowering Drugs on HCV Infectivity [PDF]
Cells, 2021 The HCV replication cycle is tightly associated with host lipid metabolism: Lipoprotein receptors SR-B1 and LDLr promote entry of HCV, replication is associated with the formation of lipid-rich membranous organelles and infectious particle assembly ...
Francisco J. Zapatero-Belinchón +10 more
doaj +2 more sources
Scavenger receptor-BI is a receptor for lipoprotein(a) [PDF]
Journal of Lipid Research, 2013 Scavenger receptor class B type I (SR-BI) is a multi-ligand receptor that binds a variety of lipoproteins, including high density lipoprotein (HDL) and low density lipoprotein (LDL), but lipoprotein(a) [Lp(a)] has not been investigated as a possible ...
Xiao-Ping Yang +9 more
doaj +3 more sources
Expanding functions of lipoprotein receptors
Journal of Lipid Research, 2009 Lipoprotein receptors are evolutionarily ancient proteins that are expressed on the surface of many cell types. Beginning with the appearance of the first primitive multicellular organisms, several structurally and functionally distinct families of ...
Joachim Herz +3 more
doaj +3 more sources
Functions of lipoprotein receptors in neurons [PDF]
Journal of Lipid Research, 2004 The LDL receptor (LDLR) family is comprised of several multifunctional cell surface proteins that bind and endocytose ligands with diverse biological functions.
Uwe Beffert +2 more
doaj +3 more sources
Characterization of the low-density lipoprotein receptors family and identification of vitellogenin receptors in Mugil cephalus [PDF]
Scientific ReportsVitellogenin receptors (VtgRs) are pivotal to the successful reproductive event in oviparous species by mediating the uptake of vitellogenin (Vtg) into developing oocytes, ensuring proper yolk formation and embryonic development.
Andrea Miccoli, Basilio Randazzo
doaj +2 more sources
PCSK9 Functions in Atherosclerosis Are Not Limited to Plasmatic LDL-Cholesterol Regulation
Frontiers in Cardiovascular Medicine, 2021 The relevance of PCSK9 in atherosclerosis progression is demonstrated by the benefits observed in patients that have followed PCSK9-targeted therapies.
Aureli Luquero +5 more
doaj +1 more source
Hepatitis C Virus Uses Host Lipids to Its Own Advantage
Metabolites, 2021 Lipids and lipoproteins constitute indispensable components for living not only for humans. In the case of hepatitis C virus (HCV), the option of using the products of our lipid metabolism is “to be, or not to be”. On the other hand, HCV infection, which
Malgorzata Sidorkiewicz
doaj +1 more source
LRP1 loss in airway epithelium exacerbates smoke-induced oxidative damage and airway remodeling
Journal of Lipid Research, 2022 The LDL receptor-related protein 1 (LRP1) partakes in metabolic and signaling events regulated in a tissue-specific manner. The function of LRP1 in airways has not been studied. We aimed to study the function of LRP1 in smoke-induced disease.
Itsaso Garcia-Arcos +13 more
doaj +1 more source
Patched, the receptor of Hedgehog, is a lipoprotein receptor [PDF]
Proceedings of the National Academy of Sciences, 2008 The Hedgehog (Hh) family of secreted signaling proteins has a broad variety of functions during metazoan development and implications in human disease. Despite Hh being modified by two lipophilic adducts, Hh migrates far from its site of synthesis and programs cellular outcomes depending on its local concentrations.
Callejo, Ainhoa +2 more
openaire +3 more sources