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GPR35 is a novel lysophosphatidic acid receptor

open access: yesGPR35 is a novel lysophosphatidic acid receptor
GPR35 is a rhodopsin-like G protein-coupled receptor identified in 1998. It has been reported that kynurenic acid, a tryptophan metabolite, may act as an endogenous ligand for GPR35. However, the concentrations of kynurenic acid required to elicit the cellular responses are usually high, raising the possibility that another endogenous ligand may exist.
openaire  

Demyelination-related pain: role of lysophosphatidic acid in satellite glial cell-neuron crosstalk. [PDF]

open access: yesJ Transl Med
Wang Y   +17 more
europepmc   +1 more source

LYSOPHOSPHATIDIC ACID RECEPTOR SIGNALING AND FUNCTION IN OSTEOBLASTS

open access: yes, 2011
Osteoblasts form bone and regulate the activity of other bone cells. Lysophosphatidic acid (LPA) is a lipid mediator that, in other systems, stimulates cell proliferation, survival and migration. We investigated LPA signaling and function in osteoblasts. Transcripts encoding multiple LPA receptors were identified.
openaire   +1 more source

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