Results 41 to 50 of about 1,067 (90)

Activation of sphingosine-1-phosphate receptors can relieve myocardial ischemia-reperfusion injury by mitigating oxidative stress and ferroptosis in cardiomyocytes. [PDF]

Int J Biol Sci
Xu X, Li R, Li S, Wei Q, Yu F, Ma G, Tong J.   +6 more
europepmc   +1 more source

Imaging and targeting S1PR1 in HER2+ tumors. [PDF]

Nucl Med Biol
Shmuel S, Qiu L, Vanover A, Chen H, Jiang H, Tu Z, Pereira PMR.   +6 more
europepmc   +1 more source

Lysophosphatidic Acid Promotes the Expansion of Cancer Stem Cells via TRPC3 Channels in Triple-Negative Breast Cancer. [PDF]

Int J Mol Sci, 2022
Hirata N, Yamada S, Yanagida S, Ono A, Yasuhiko Y, Nishida M, Kanda Y.   +6 more
europepmc   +1 more source

Sphingosine 1-phosphate receptor 1signaling in macrophages reduces atherosclerosis in LDL receptor-deficient mice. [PDF]

JCI Insight
Potì F, Scalera E, Feuerborn R, Fischer J, Arndt L, Varga G, Pardali E, Seidl MD, Fobker M, Liebisch G, Hesse B, Lukasz AH, Rossaint J, Kehrel BE, Rosenbauer F, Renné T, Christoffersen C, Simoni M, Burkhardt R, Nofer JR.   +19 more
europepmc   +1 more source

Sphingosine-1-phosphate receptor 1 activation in the central nervous system drives cisplatin-induced cognitive impairment. [PDF]

J Clin Invest, 2022
Squillace S, Niehoff ML, Doyle TM, Green M, Esposito E, Cuzzocrea S, Arnatt CK, Spiegel S, Farr SA, Salvemini D.   +9 more
europepmc   +1 more source

The novel sphingosine-1-phosphate receptor modulator KRP-203 prevents myocardial ischemia-reperfusion injury by preserving mitochondrial function through activation of the RISK and SAFE signaling pathways. [PDF]

Cell Biol Toxicol
Wu N, Wang L, Yu S, Wei X, Xu H, Xu S, Jia P, Zhang X.   +7 more
europepmc   +1 more source

Paracrine signaling mediators of vascular endothelial barrier dysfunction in sepsis: implications for therapeutic targeting. [PDF]

Tissue Barriers
Puthiyottil S, Skaria T.
europepmc   +1 more source

Effect of exercise preconditioning on myocardial content of Sphingosine1-phosphate and its mechanism in rats after exhaustive exercise. [PDF]

PLoS One
Wei X, Yang W, Zhou J, Cao L, Jiang W.
europepmc   +1 more source

In-silico characterization of deleterious non-synonymous SNPs in the human S1PR1 gene reveals structural instability and altered ligand affinity. [PDF]

PLoS One
Biswas S, Sardar D, Hossain MA, Hasnat S, Ramjan AH, Nazifa UK, Zohora FT, Esha IJ, Mondal C, Barik A, Hoque MN.   +10 more
europepmc   +1 more source

Sphingosine-1-Phosphate Receptor 2 Promotes Renal Microvascular Constriction and Kidney Injury Following Renal Ischemia-Reperfusion in Rats. [PDF]

Function (Oxf)
Guan Z, Remedies CE, Zhang Y, Sanders PW, Inscho EW, Feng W.   +5 more
europepmc   +1 more source