Results 21 to 30 of about 1,067 (90)

Metabolic pathways in immune senescence and inflammaging: Novel therapeutic strategy for chronic inflammatory lung diseases. An EAACI position paper from the Task Force for Immunopharmacology

Allergy, Volume 79, Issue 5, Page 1089-1122, May 2024.
Abstract The accumulation of senescent cells drives inflammaging and increases morbidity of chronic inflammatory lung diseases. Immune responses are built upon dynamic changes in cell metabolism that supply energy and substrates for cell proliferation, differentiation, and activation.
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. C. A. M. Van Esch, C. Stellato   +19 more
wiley   +1 more source

Pathogen Recognition by the Long Pentraxin PTX3

BioMed Research International, Volume 2011, Issue 1, 2011., 2011
Innate immunity represents the first line of defence against pathogens and plays key roles in activation and orientation of the adaptive immune response. The innate immune system comprises both a cellular and a humoral arm. Components of the humoral arm include soluble pattern recognition molecules (PRMs) that recognise pathogen‐associated molecular ...
Federica Moalli, Sebastien Jaillon, Antonio Inforzato, Marina Sironi, Barbara Bottazzi, Alberto Mantovani, Cecilia Garlanda, Jie-Oh Lee   +7 more
wiley   +1 more source

Bioorthogonal azido-S1P works as substrate for S1PR1. [PDF]

J Lipid Res, 2023
Sternstein C, Schlegel J, Sauer M, Seibel J.   +3 more
europepmc   +1 more source

Dissecting the Therapeutic Mechanisms of Sphingosine-1-Phosphate Receptor Agonism during Ischaemia and Reperfusion. [PDF]

Int J Mol Sci, 2023
Wilkins GC, Gilmour J, Giannoudaki E, Kirby JA, Sheerin NS, Ali S.   +5 more
europepmc   +1 more source

Sphingosine-1-Phosphate Receptor and Kinase Expression in the Reproductive Tract Is Associated with HIV Infection and Preterm Birth in a Cohort of Pregnant Women in Zambia. [PDF]

Viruses
Resop RS, Mwape I, Sebastião YV, Rittenhouse KJ, Sindano N, Mwape H, Kasaro MP, Vwalika B, Price JT, Stringer JSA, De Paris K.   +10 more
europepmc   +1 more source

Sphingosine-1-Phosphate Receptor 3 Induces Endothelial Barrier Loss via ADAM10-Mediated Vascular Endothelial-Cadherin Cleavage. [PDF]

Int J Mol Sci, 2023
Wu J, Liang Y, Fu P, Feng A, Lu Q, Unwalla HJ, Marciano DP, Black SM, Wang T.   +8 more
europepmc   +1 more source

Expression of sphingosine-1-phosphate receptor 1 in the brain of fatal cerebral malaria. [PDF]

Sci Rep
Srisook C, Nintasen R, Punsawad C, Glaharn S, Techarang T, Viriyavejakul P.   +5 more
europepmc   +1 more source

Aberrant sphingosine-1-phosphate receptor 1 expression on activated naive B cells associated with disease activity and lupus nephritis in systemic lupus erythematosus. [PDF]

Arthritis Res Ther
Tianpothong P, Kochayoo P, Suangtamai T, Suksapan S, Thawornpan P, Leepiyasakulchai C, Ngamjanyaporn P, Pisitkun P, Chootong P.   +8 more
europepmc   +1 more source

Sphingosine-1-phosphate receptor 2 inhibition ameliorates familial exudative vitreoretinopathy models. [PDF]

J Biol Chem
Feridooni HA, Fody R, Tavasoli M, Alkandari M, van der Ende S, Nader M, Robitaille JM, McMaster CR.   +7 more
europepmc   +1 more source

Structural insights into subtype-specific agonist recognition by sphingosine-1-phosphate receptors. [PDF]

PLoS Biol
Yu L, Jiao H, Pang B, Ti R, Gan B, Qin Z, Wang J, Zhu L, Hu H, Ren R.   +9 more
europepmc   +1 more source