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Metabotropic glutamate receptors and neurodegeneration.
Progress in brain research, 1998Metabotropic glutamate (mGlu) receptors belong to a class of G-protein linked receptors, which also includes the Ca2+-sensing receptor and the gama-aminobutyric acid (GABAB) receptor. A great variety of drugs has been introduced with the intent of limiting some of the intracellular events that occur downstream of the increase in intracellular Ca2 ...
BRUNO, Valeria Maria Gloria +7 more
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Metabotropic Glutamate Receptors and Neuronal Toxicity
1992Specific glutamate receptors coupled to polyphosphoinositide (PPI) hydrolysis have been described in brain slices, cultured neurons, and astrocytes, and in amphibian oocytes injected with rat brain mRNA (Sladeczek et al., 1985; Nicoletti et al., 1986a,b; Sugiyama et al., 1987).
ALEPPO G +7 more
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Modulation of Excitation by Metabotropic Glutamate Receptors
2007Metabotropic glutamate receptors, in contrast to ionotropic glutamate receptors, do not form ion channels but instead affect intracellular chemical messenger systems. They couple via GTP-binding proteins ("G-proteins") to a variety of effectors such as ion channels and thus give glutamate, the major excitatory transmitter in the CNS, the ability to ...
Thomas, Knöpfel, Marylka, Uusisaari
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[Metabotropic glutamate receptors].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1997R, Minakami, H, Sugiyama
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Metabotropic glutamate receptors and neuroprotection.
1998NICOLETTI, Ferdinando +10 more
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