Results 201 to 210 of about 126,867 (267)

The Cheung Glutamatergic Regimen as a candidate for primary and secondary prevention of Alzheimer's disease onset. [PDF]

J Alzheimers Dis Rep
Cheung N.
europepmc   +1 more source

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Structures of Gi-bound metabotropic glutamate receptors mGlu2 and mGlu4

Nature, 2021
Shuling Lin, Shuo Han, Xiao-qing Cai, Q. Tan, Ke Zhou, Dejian Wang, Xinwei Wang, Juan Du, C. Yi, Xiaojing Chu, A. Dai, Yan Zhou, Yan Chen, Yu Zhou, Hong Liu, Jianfeng Liu, Dehua Yang, Ming-Wei Wang, Qiang Zhao, Beili Wu   +19 more
semanticscholar   +3 more sources

Metabotropic glutamate receptors

Cell and Tissue Research, 2006
Metabotropic glutamate receptors (mGlus) are a family of G-protein-coupled receptors activated by the neurotransmitter glutamate. Molecular cloning has revealed eight different subtypes (mGlu1-8) with distinct molecular and pharmacological properties. Multiplicity in this receptor family is further generated through alternative splicing. mGlus activate
Ferraguti F., Shigemoto R.
  +6 more sources

Metabotropic glutamate receptors

Pharmacology Biochemistry and Behavior, 2002
Abstract Glutamate, like other neurotransmitters (acetylcholine, ATP, serotonine, glycine, GABA), acts on two main types of membrane receptors: ligand-gated channels, also called ionotropic receptors (iGluRs), and G protein coupled receptors also called metabotropic glutamate receptors (mGluRs).
Darryle D Schoepp, P.Jeffrey Conn
  +5 more sources

International Union of Basic and Clinical Pharmacology. CXI. Pharmacology, Signaling, and Physiology of Metabotropic Glutamate Receptors

Pharmacological Reviews, 2020
Metabotropic glutamate (mGlu) receptors respond to glutamate, the major excitatory neurotransmitter in the mammalian brain, mediating a modulatory role that is critical for higher-order brain functions such as learning and memory.
K. Gregory, C. Goudet
semanticscholar   +1 more source

Pharmacological agents acting at subtypes of metabotropic glutamate receptors.

Neuropharmacology, 1999
D. Schoepp, D. Jane, J. Monn
semanticscholar   +3 more sources

Expression cloning of GABAB receptors uncovers similarity to metabotropic glutamate receptors

Nature, 1997
K. Kaupmann, K. Huggel, J. Heid, P. Flor, S. Bischoff, S. J. Mickel, G. Mcmaster, C. Angst, H. Bittiger, W. Froestl, B. Bettler   +10 more
semanticscholar   +3 more sources

Metabotropic Glutamate Receptors

Amino Acids, 2007
l-Glutamate, one of the main neurotransmitters in the central nervous system (CNS), acts on two groups of receptors: (a) a group of ionotropic receptors that includes N-methyl-d-aspartate (NMDA), α-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA), and kainate receptors, and (2) a group of metabotropic receptors (mGluRs).
A. Pilc, K. Ossowska
openaire   +2 more sources