Results 71 to 80 of about 126,867 (267)

Glutamatergic system components as potential biomarkers and therapeutic targets in cancer in non-neural organs

Frontiers in Endocrinology, 2022
Glutamate is one of the most abundant amino acids in the blood. Besides its role as a neurotransmitter in the brain, it is a key substrate in several metabolic pathways and a primary messenger that acts through its receptors outside the central nervous ...
Ana Cristina García-Gaytán, Andy Hernández-Abrego, Mauricio Díaz-Muñoz, Isabel Méndez   +3 more
doaj   +1 more source

Foreign Language Learning in Older Adults Modifies Resting‐State Functional Connectivity Between the Subcortical Structures and the Cortex

AGING MEDICINE, EarlyView.
Foreign language learning in older adults reorganizes thalamic and caudate connectivity, in a process topographically overlapping with the expression of receptors and genes related to neuroplasticity. ABSTRACT Objectives Neuroimaging studies suggest that Foreign Language Learning (FLL) influences resting‐state functional connectivity (rs‐FC) within the
Giovanna Bubbico, Federica Tomaiuolo, Carlo Sestieri, Golnoush Akhlaghipour, Alberto Granzotto, Antonio Ferretti, Mauro Gianni Perrucci, Stefano L. Sensi, Stefano Delli Pizzi   +8 more
wiley   +1 more source

Morphological plasticity of astroglia: Understanding synaptic microenvironment [PDF]

, 2015
Memory formation in the brain is thought to rely on the remodeling of synaptic connections which eventually results in neural network rewiring. This remodeling is likely to involve ultrathin astroglial protrusions which often occur in the immediate ...
Heller, JP, Rusakov, DA
core   +1 more source

Autism and Cortical Thickness Deviation From Neurotypical Controls: Evidence for a Spatial Association With Serotonin Receptors

Autism Research, EarlyView.
ABSTRACT Cortical thickness (CT) differences between autistic individuals (AI) and neurotypical controls have been consistently reported, yet the neurochemical mechanisms underlying these differences remain insufficiently understood. Neurotransmitter receptor systems exhibit distinct spatial distributions across the cortex and influence synaptic ...
Livio Tarchi, Arne Doose, Julius Hennig, Fabio Bernardoni, Joseph A. King, Tiziana Pisano, Giovanni Castellini, Valdo Ricca, Inge Kamp‐Becker, Stefan Ehrlich   +9 more
wiley   +1 more source

Cross-talk and regulation between glutamate and GABAB receptors

Frontiers in Cellular Neuroscience, 2015
Brain function depends on co-ordinated transmission of signals from both excitatory and inhibitory neurotransmitters acting upon target neurons.
Sriharsha eKantamneni
doaj   +1 more source

Blunted Cystine–Glutamate Antiporter Function in the Nucleus Accumbens Promotes Cocaine-induced Drug Seeking [PDF]

, 2008
Repeated cocaine alters glutamate neurotransmission, in part, by reducing cystine–glutamate exchange via system xc−, which maintains glutamate levels and receptor stimulation in the extrasynaptic compartment.
Abdulhameed, Omer, Baker, David A., Grier, Mark D., Kau, Kristen S., Madayag, Aric, Mantsch, John R.   +5 more
core   +1 more source

Wwox deletion leads to reduced GABA-ergic inhibitory interneuron numbers and activation of microglia and astrocytes in mouse hippocampus [PDF]

, 2019
The association of WW domain-containing oxidoreductase WWOX gene loss of function with central nervous system (CNS) related pathologies is well documented.
Abba, Martín Carlos, Aldaz, Claudio Marcelo, Attaluri, Sahithi, Hattiangady, Bharathi, Hussain, Tabish, Kil, Hyunsuk, Kodali, Maheedhar, Lee, Jaeho, Shen, Jianjun, Shetty, Ashok K., Shuai, Bing, Takata, Yoko   +11 more
core   +2 more sources

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Cardiovascular responses to microinjection of trans-(±)-ACPD into the NTS were similar in conscious and chloralose-anesthetized rats

Brazilian Journal of Medical and Biological Research, 1998
The changes in mean arterial pressure (MAP) and heart rate (HR) in response to the activation of metabotropic receptors in the nucleus tractus solitarii (NTS) with trans-(±)-1-amino-1,3-cyclopentanedicarboxylic acid (trans-(±)-ACPD) were evaluated in ...
B.H. Machado, L.G.H. Bonagamba
doaj   +1 more source

Glutamate, GABA and acetylcholine signaling components in the lamina of the Drosophila visual system. [PDF]

PLoS ONE, 2008
Synaptic connections of neurons in the Drosophila lamina, the most peripheral synaptic region of the visual system, have been comprehensively described.
Agata Kolodziejczyk, Xuejun Sun, Ian A Meinertzhagen, Dick R Nässel   +3 more
doaj   +1 more source