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Evolution of the Mineralocorticoid Receptor
2019The mineralocorticoid receptor (MR) and its kin, the glucocorticoid receptor (GR) evolved from an ancestral corticoid receptor (CR) in a cyclostome (jawless fish) through gene duplication and divergence. Distinct MR and GR orthologs first appear in cartilaginous fishes, such as sharks, skates, rays and chimaeras.
Michael E, Baker, Yoshinao, Katsu
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Mineralocorticoid Receptors: Distribution and Activation
Heart Failure Reviews, 2005Mineralocorticoid receptors (MR) bind both mineralocorticoids and glucocorticoids with high affinity (deoxycorticosterone = corticosterone >/= aldosterone = cortisol), and are found in both Na(+) transporting epithelia (e.g. kidney, colon) and nonepithelial tissues (e.g. heart, brain).
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The role of mineralocorticoid receptor activation in kidney inflammation and fibrosis
Kidney International Supplements, 2022James M Luther
exaly
Brain Mineralocorticoid Receptor Functiona
Annals of the New York Academy of Sciences, 1994E R, de Kloet +3 more
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Cyproheptadine and Mineralocorticoid Receptors
New England Journal of Medicine, 1982ARMANINI, DECIO, KARBOWIAK I, FUNDER J.
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Proceedings of the National Academy of Sciences of the United States of America, 2005
Henk Karst, Günther Schütz
exaly
Henk Karst, Günther Schütz
exaly
Mineralocorticoid receptor isoforms
Current Opinion in Endocrinology and Diabetes, 1998Maria-Christina Zennaro, Marc Lombès
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