Results 101 to 110 of about 85,647 (239)

Regulation of Neuromodulator Receptor Efficacy - Implications for Whole-Neuron and Synaptic Plasticity [PDF]

, 2004
Membrane receptors for neuromodulators (NM) are highly regulated in their distribution and efficacy - a phenomenon which influences the individual cell's response to central signals of NM release.
Scheler, Gabriele
core   +1 more source

Respiratory dysfunction and fatal apnea during pilocarpine‐induced status epilepticus

Epilepsia, EarlyView.
Abstract Objective Status epilepticus (SE) is second only to sudden unexpected death in epilepsy as a cause of seizure‐related mortality. The progression of respiratory dysfunction during experimental SE remains poorly characterized. We investigated how pilocarpine‐induced SE affects respiration in mice.
Chengsan Sun, Rachel Spera, John M. Williamson, Suchitra Joshi, Bhavya Guduru, Harini Ganabady, Jaideep Kapur   +6 more
wiley   +1 more source

Activation of muscarinic acetylcholine receptors elicits pigment granule dispersion in retinal pigment epithelium isolated from bluegill

BMC Neuroscience, 2004
Background In fish, melanin pigment granules in the retinal pigment epithelium disperse into apical projections as part of the suite of responses the eye makes to bright light conditions.
Crittenden Elizabeth L, González Alfredo, García Dana M   +2 more
doaj   +1 more source

Generation of Choline for Acetylcholine Synthesis by Phospholipase D Isoforms [PDF]

, 2001
DEDICATION: This article is dedicated to the memory of Sue Kim Hanson, a graduate student in the department of Pathology and Laboratory Medicine at Boston University School of Medicine, who perished in the terrorist attacks of September 11, 2001 ...
Blusztajn, Jan Krzysztof, Frohman, Michael A, Zhao, Di   +2 more
core   +3 more sources

Spreading depolarization and its influence on epileptiform activity

Epilepsia, EarlyView.
Abstract Spreading depolarization (SD) is a transient disruption of electrographic activity that slowly propagates through the gray matter by chemical contiguity, and it is characterized by a large depolarization of neurons and glial cells. SD, which is associated with massive changes in ion homeostasis, including extreme increases in [K+]o, was shown ...
Maxime Lévesque, Rüdiger Köhling, Massimo Avoli   +2 more
wiley   +1 more source

Allosteric Modulation of Muscarinic Acetylcholine Receptors

Pharmaceuticals, 2010
An allosteric modulator is a ligand that binds to an allosteric site on the receptor and changes receptor conformation to produce increase (positive cooperativity) or decrease (negative cooperativity) in the binding or action of an orthosteric agonist (e.
Esam E. El-Fakahany, Jan Jakubík
doaj   +1 more source

Management of an uncommon complication using botulinum toxin type A following prosthetic laryngoplasty

Equine Veterinary Education, EarlyView.
Summary An uncommon complication following prosthetic laryngoplasty was reported in a 4‐year‐old Andalusian mare. The mare was presented with a previously diagnosed left‐sided recurrent laryngeal neuropathy, after initial evaluation the mare underwent ventriculocordectomy and prosthetic laryngoplasty.
J. L. Sanclemente, D. S. Larriva, C. A. Ragle   +2 more
wiley   +1 more source

Cardiac muscarinic receptor overexpression in sudden infant death syndrome.

PLoS ONE, 2010
BackgroundSudden infant death syndrome (SIDS) remains the leading cause of death among infants less than 1 year of age. Disturbed expression of some neurotransmitters and their receptors has been shown in the central nervous system of SIDS victims but no
Angelo Livolsi, Nathalie Niederhoffer, Nassim Dali-Youcef, Caroline Rambaud, Catherine Olexa, Walid Mokni, Jean-Pierre Gies, Pascal Bousquet   +7 more
doaj   +1 more source

Arctic lake trout (Salvelinus namaycush) show evidence of seasonal acclimation of cardiac adrenergic sensitivity but not heat tolerance

Journal of Fish Biology, EarlyView.
Abstract Many Arctic fishes experience prolonged periods of extreme cold and large thermal variation over both rapid and seasonal time scales which challenge critical physiological functions. In the central Canadian Arctic, we caught wild adult lake trout (Salvelinus namaycush) acclimatized to winter and summer temperatures to determine the extent to ...
Emily P. Williams, Les N. Harris, Jean‐Sébastien Moore, Ella K. Middleton, Shira A. Berkelhammer, Ben Speers‐Roesch, Matthew J. H. Gilbert   +6 more
wiley   +1 more source

Second Asian Consensus Report on Functional Dyspepsia (2025): Updated Recommendations

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Functional dyspepsia (FD) is a common gastrointestinal disorder that significantly impacts patients' quality of life. Over a decade ago, the Asian Neurogastroenterology and Motility Association (ANMA) and the Asian Pacific Association of Gastroenterology (APAGE) jointly developed the first Asian consensus report on FD.
Sanjiv Mahadeva, Kewin Tien Ho Siah, Uday C. Ghoshal, Hidekazu Suzuki, Yeong Yeh Lee, Kee Huat Chuah, Vincent Chung, Linda Zhong, Benjamin Wei‐Rong Tay, Ban Hong Ang, Ram Prasad Sinnanaidu, Tao Bai, Tadayuki Oshima, Tanisa Patcharatrakul, Sanjeev Sachdeva, Ping‐Huei Tseng, Jinsong Liu, Yinglian Xiao, Ratha‐Korn Vilaichone, Joon Seong Lee, Jung‐Hwan Oh, Ari Fahrial Syam, Ching Liang Lu, Tiing Leong Ang, In‐Kyung Sung, Xiao‐Hua Hou, Kentaro Sugano, Justin Wu, Hiroto Miwa   +28 more
wiley   +1 more source