Results 151 to 160 of about 2,302,872 (259)

Feed‐induced hypersalivation in horses from Austria, Germany and Switzerland

Equine Veterinary Journal, Volume 57, Issue 4, Page 1035-1043, July 2025.
Abstract Background While previous reports come mostly from the southern Americas, several outbreaks of hypersalivation in horses were observed in Middle Europe from 2016 to 2018. Objective To describe feed‐induced hypersalivation in European horses. Study design Analysis of feedstuffs.
Linda Franziska Böswald, Christoph Gottschalk, Florian Kaltner, Joana Merk, Karin Schwaiger, Ellen Kienzle   +5 more
wiley   +1 more source

Synthesis and Characterization of Photoswitchable Covalent Ligands for the β2‐Adrenoceptor

Angewandte Chemie, Volume 137, Issue 24, June 10, 2025.
A structure‐based design of a covalent photoswitchable ligand for the β2‐adrenergic receptor, a therapeutically relevant GPCR, is described. This tool facilitates the modification of the intrinsic activity of the protein by light. Computational analysis of its mechanism of action suggests that the photoswitch takes place within the binding pocket ...
Ulrike Wirth, Eduard Neu, Davide Provasi, Steffen Feustel, Maximilian F. Schmidt, Harald Hübner, Dorothée Weikert, Marta Filizola, Burkhard König, Peter Gmeiner   +9 more
wiley   +2 more sources

Clozapine: past, present and future. [PDF]

World Psychiatry
Correll CU.
europepmc   +1 more source

Decoding Gastric Reflexes: The Role of Mechanosensitive Enteric Neurons in Stomach Motility

Neurogastroenterology &Motility, Volume 37, Issue 7, July 2025.
ABSTRACT This review focuses on mechanosensitive enteric neurons (MEN) in the guinea pig stomach and their roles in gastric motor reflex pathways. The guinea pig model is advantageous for studying gastric physiology, as its stomach structure and function closely resemble those of humans. Gastric motility involves distinct functional regions: the fundus
Gemma Mazzuoli‐Weber, Sophia Mayr, Kristin Elfers   +2 more
wiley   +1 more source

Acetylcholine in the hippocampus: problems and achievements. [PDF]

Front Neural Circuits
Dobryakova YV, Bolshakov AP, Korotkova T, Rozov AV.   +3 more
europepmc   +1 more source

The effect of seasonal heat acclimatization on cool‐seeking behaviour during passive heat stress in young adults

Experimental Physiology, Volume 110, Issue 7, Page 992-1004, 1 July 2025.
Abstract Seasonal heat acclimatization is known to enhance autonomic thermoeffector responses, whereas the behavioural response following seasonal heat acclimatization remains unknown. We investigated whether seasonal heat acclimatization would alter autonomic and behavioural thermoregulatory responses.
Hui Wang, Zachary J. Schlader, Tze‐Huan Lei, Toby Mündel, Tatsuro Amano, Naoto Fujii, Takeshi Nishiyasu, James Cotter, Narihiko Kondo   +8 more
wiley   +1 more source

The mechanism of action of clozapine. [PDF]

J Psychopharmacol
Morrison PD, Jauhar S, Young AH.
europepmc   +1 more source

Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand

Proceedings of the National Academy of Sciences of the United States of America, 2007
Blaine N. Armbruster, Xiang Li, M. Pausch, S. Herlitze, B. Roth   +4 more
semanticscholar   +1 more source

Benzochalcogenodiazoles, Synthesis, and Applications in Medicinal Chemistry and Photomedicine

European Journal of Organic Chemistry, Volume 28, Issue 23, June 23, 2025.
Benzochalcogenodiazoles (BXD) including benzoxadiazoles, benzothiadiazoles, and benzoselenadiazoles are initially mainly designed for optoelectronic materials as electron‐deficient cores. Nevertheless, they are now extending their application to biology.
Jean‐Elie Zheng, Xavier Franck, Thibault Gallavardin   +2 more
wiley   +1 more source