Results 191 to 200 of about 83,236 (271)

A Scoping Review of Pathogenesis, Current Treatments, and Novel Approaches for Vitiligo

Journal of Cosmetic Dermatology, Volume 24, Issue 10, October 2025.
ABSTRACT Background Vitiligo is a chronic skin disorder characterized by loss of melanocytes, causing depigmentation and psychological distress. Its pathogenesis is complex and multifactorial, involving genetic predisposition, autoimmune, oxidative stress, and neurogenic mechanisms.
Nusaibah Sallehuddin, Nur Izzah Md Fadilah, Mh Busra Fauzi, Manira Maarof   +3 more
wiley   +1 more source

The impact of muscarinic and mGlu receptors modulators on MK-801-induced impairments in NO-dependent processes both in vitro and in vivo. [PDF]

Pharmacol Rep
Burnat G, Santocki M, Kalinowski L, Wierońska JM.   +3 more
europepmc   +1 more source

Closing the Evidence Gap: Retrospective and Prospective Strategies to Advance Aripiprazole's Potential Benefits in Patients With Cancer

Pharmacology Research &Perspectives, Volume 13, Issue 5, October 2025.
Elvira Meni Maria Gkrinia, Marin Golčić, Andrej Belančić   +2 more
wiley   +1 more source

Evaluation of the Efficacy of Metformin in the Treatment of Acne Vulgaris and Its Effects on Serum Lipid Metabolism

Journal of Cosmetic Dermatology, Volume 24, Issue 10, October 2025.
ABSTRACT Background Acne vulgaris (AV) is a common inflammatory skin disease during adolescence. Metformin (MET) has recently been found to have the effects of regulating lipid disorders, suggesting its potential benefits in the treatment of AV patients. Method Recruited 18 patients with moderate to severe AV, and then received MET treatment (AVM group)
Jie Hu, Yuxin He, Peiyang Du, Yongqiong Deng, Xia Xiong, Yaxin Huang   +5 more
wiley   +1 more source

Evidence for M2 Muscarinic Receptor Antagonist Delay of Myopia Development Through Activation of Kir3.4 Channel in the Retina of Guinea Pigs. [PDF]

Invest Ophthalmol Vis Sci
Zhou H, Zhou G, Yang Q, Niu J, Wang R, Liu H, Hou S, Bi H, Liao X.   +8 more
europepmc   +1 more source

Shear Stress Regulates ABCA1‐Dependent Membrane Cholesterol Content in Endothelial Cells Facilitating H2S‐Dependent Vasodilation

Microcirculation, Volume 32, Issue 7, October 2025.
ABSTRACT Endothelial cells (ECs) express an array of integral membrane proteins, including ion channels and transporters that contribute to blood flow regulation and cell–cell communication. Many of these membrane proteins are regulated by plasma membrane cholesterol content.
Jacob R. Anderson, Nancy L. Kanagy, Laura V. Gonzalez Bosc, Jay S. Naik   +3 more
wiley   +1 more source

Induction of chronic prostatitis does not alter the innate contractile properties of the prostate or urethra in rats. [PDF]

Sci Rep
Aydogdu O, Black G, Aronsson P, Carlsson T, Winder M.   +4 more
europepmc   +1 more source

Enteric glial S100B controls rhythmic colonic functions by regulating excitability and specificity in gut motor neurocircuits

The Journal of Physiology, Volume 603, Issue 19, Page 5723-5749, October 1, 2025.
Abstract figure legend During colonic motor complex activity, enteric glia play a pivotal role by releasing the S100 calcium‐binding protein B (S100B). This gliotransmitter has both intra‐ and extracellular functions, including the regulation of neuronal and glial excitability within the enteric nervous system.
Beatriz Thomasi, Rafaella Lavalle, Jonathon L. McClain, Julia Jamka, Luisa Seguella, Brian D. Gulbransen   +5 more
wiley   +1 more source

Primary Cilia and Cardiovascular Risk Factors in Alzheimer's Disease. [PDF]

Brain Sci
Sunderman CL, Forero KV, Alorjani Q, Buqaileh R, Gallagher GM, Ventresca SM, Messer WS, AbouAlaiwi WA.   +7 more
europepmc   +1 more source

Autonomic effects of electroacupuncture in opioid‐induced constipation in male rats

Physiological Reports, Volume 13, Issue 19, October 2025.
Abstract The efficacy of electroacupuncture (EA) for opioid‐induced constipation (OIC) has been reported; however, the mechanism has not been sufficiently studied, and the details have not been clarified. The aims of this study were to demonstrate the delay in rat colonic transit (CT) caused by loperamide, a peripheral μ‐opioid receptor agonist, and to
Misaki Okada, Kazunori Itoh, Hiroshi Kitakoji, Kenji Imai   +3 more
wiley   +1 more source