Results 231 to 240 of about 156,800 (338)

Synaptic ultrastructural alterations in human focal cortical dysplasia: Insights from volume electron microscopy

open access: yesEpilepsia, EarlyView.
Abstract Objective Focal cortical dysplasia (FCD) is a developmental malformation of the cerebral cortex and a leading cause of drug‐resistant epilepsy in children and young adults. Disruption of the excitation–inhibition (E–I) balance is a hallmark of neuronal hyperexcitability in FCD, yet the underlying synaptic ultrastructural changes remain poorly ...
Gyu Hyun Kim   +6 more
wiley   +1 more source

Low frequency of N-methyl-D-aspartate receptor autoimmunity in tick-borne encephalitis. [PDF]

open access: yesPLoS One
Morén J   +8 more
europepmc   +1 more source

Respiratory dysfunction and fatal apnea during pilocarpine‐induced status epilepticus

open access: yesEpilepsia, EarlyView.
Abstract Objective Status epilepticus (SE) is second only to sudden unexpected death in epilepsy as a cause of seizure‐related mortality. The progression of respiratory dysfunction during experimental SE remains poorly characterized. We investigated how pilocarpine‐induced SE affects respiration in mice.
Chengsan Sun   +6 more
wiley   +1 more source

Aβ neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-d-aspartate receptors

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2012
Haitao You   +9 more
semanticscholar   +1 more source

The interacting etiologies of hippocampal sclerosis in epilepsy: A scoping review

open access: yesEpilepsia, EarlyView.
Abstract According to the International League Against Epilepsy classification, mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE‐HS) is considered an epilepsy syndrome. Several etiologies may precede HS, but there is little overview in the literature about these etiologies.
Boris Deleu   +2 more
wiley   +1 more source

The NMDA Receptor Antagonist Memantine Modulates Aging and Stress Resilience. [PDF]

open access: yesAging Cell
Juozaityte V   +8 more
europepmc   +1 more source

Presynaptic N-methyl-D-aspartate receptors at the parallel fiber-Purkinje cell synapse.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2000
M. Casado   +2 more
semanticscholar   +1 more source

Spreading depolarization and its influence on epileptiform activity

open access: yesEpilepsia, EarlyView.
Abstract Spreading depolarization (SD) is a transient disruption of electrographic activity that slowly propagates through the gray matter by chemical contiguity, and it is characterized by a large depolarization of neurons and glial cells. SD, which is associated with massive changes in ion homeostasis, including extreme increases in [K+]o, was shown ...
Maxime Lévesque   +2 more
wiley   +1 more source

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