Results 231 to 240 of about 155,151 (336)

Chloral Hydrate's Impact on Brain Development: From Clinical Safety to Molecular Mechanisms. [PDF]

Drug Des Devel Ther
Deng P, Zhu C, Zhang J, Zhu L, Xiao T, Qu S.   +5 more
europepmc   +1 more source

Evaluation of glycine treatment for reducing alcohol craving and self‐administration in individuals with alcohol use disorder: A human laboratory trial

Alcohol, Clinical and Experimental Research, EarlyView.
This RCT evaluated whether the glycine receptor (GlyR) agonist glycine reduces craving and alcohol intake in individuals with AUD. Despite a preclinical rationale for targeting the GlyR, these parameters were not reduced. Interestingly, glycine weakened the link between alcohol‐induced craving and self‐administration, and baseline glycine levels were ...
Yasmin Olsson, Helga Lidö, Mia Ericson, Bo Söderpalm   +3 more
wiley   +1 more source

Dimeric gold nanoparticles enable multiplexed labeling in cryoelectron tomography. [PDF]

Proc Natl Acad Sci U S A
Kim H, Spangler CJ, Matsui A, Elferich J, Kim J, Roseborough A, Nyman M, Lahtinen TM, Gouaux E.   +8 more
europepmc   +1 more source

Pharmacological and Mechanistic Interventions for Cognitive Impairment Associated With Schizophrenia: A Review of Registered Clinical Trials

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Schizophrenia is characterized by positive, negative, and cognitive symptoms. Current pharmacological treatments often fail to address cognitive deficits. In this review of clinical trials, we aim to identify studies that explore neurobiological (non‐psychological) strategies to address Cognitive Impairment Associated with ...
Bahareh Peyrovian, Lena Palaniyappan, Theodore T. Kolivakis, Howard C. Margolese   +3 more
wiley   +1 more source

The Synaptic and Intrinsic Cellular Mechanisms of Persistent Firing in Neurogliaform Cells. [PDF]

Biomolecules
Chen S, Chen X, Zhou J, Wang J, Li K, Xie W, Long C, Wu G.   +7 more
europepmc   +1 more source

Effects of Intravenous Ketamine on Posttraumatic Stress Disorder (PTSD): A Systematic Review

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Posttraumatic stress disorder (PTSD) is a mental disorder resulting from exposure to traumatic events. Evidence suggests that ketamine may be efficacious in treating PTSD, however, ketamine's mechanisms in treating PTSD remain unclear. Herein, this review aims to evaluate the clinical outcomes of ketamine treatment in persons with
Liyang Yin, Andy Lu, Gia Han Le, Christine E. Dri, Sabrina Wong, Kayla M. Teopiz, Heidi Xu, Roger Ho, Taeho Greg Rhee, Heidi Ka Ying Lo, Maria‐Christina Sioufi, Yang Jing Zheng, Hezekiah C. T. Au, Hernan F. Guillen‐Burgos, Bing Cao, Roger S. McIntyre   +15 more
wiley   +1 more source

Alterations of NMDAR Subunits in the Cerebrospinal Fluid Across Neurodegenerative and Immunological Disorders. [PDF]

J Neurochem
Escamilla S, Pérez-González R, Márquez-Marco C, Camporesi E, Brinkmalm G, Padovani A, Pilotto A, Tolassi C, Arici D, Volonghi I, Zetterberg H, Blennow K, Pérez-Pérez J, Kulisevsky J, Cuchillo-Ibáñez I, Sáez-Valero J.   +15 more
europepmc   +1 more source

Presynaptic N-methyl-D-aspartate receptors at the parallel fiber-Purkinje cell synapse.

Proceedings of the National Academy of Sciences of the United States of America, 2000
M. Casado, Stéphane Dieudonné, P. Ascher   +2 more
semanticscholar   +1 more source

Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review

Addiction, EarlyView.
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper, Francesca Small, Sam Brown, Michael Kelleher, Luke Mitcheson, James Rucker, Allan H. Young, John Marsden   +7 more
wiley   +1 more source

Differential Astrocyte-Supplied NMDAR Co-Agonist for CA1 Versus Dentate Gyrus Long-Term Potentiation. [PDF]

Hippocampus
Sateesh S, Abraham WC.
europepmc   +1 more source