Results 231 to 240 of about 100,886 (308)

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, Volume 183, Issue 7, Page 1313-1340, April 2026.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

An <i>in silico</i> pipeline identifies new neuropeptides and reveals a non-amidated regulator of muscle contraction in the freshwater cnidarian <i>Hydra</i>. [PDF]

Open Biol
Prabhu P, Reddy PC.
europepmc   +1 more source

The differences in local translatome across distinct neuron types is mediated by both baseline cellular differences and post-transcriptional mechanisms [PDF]

, 2018
Aryal, Shivani, Dougherty, Joseph D, Lagunas, Tomas, Lake, Allison M, Ouwenga, Rebecca   +4 more
core   +1 more source

Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control

The Journal of Physiology, EarlyView.
Richard J. A. Wilson, Nicholas Jendzjowsky   +1 more
wiley   +1 more source

Diabetic kidney disease, biomarkers, and finerenone

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2582-2593, April 2026.
Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley   +1 more source

Neuroplasticity and neuroimmune interactions with type 2 inflammation in asthma. [PDF]

Eur Respir Rev
Koster CS, Lavitola C, Teodorescu R, Bakker BA, Gosens R.   +4 more
europepmc   +1 more source

Interictal and Ictal Cognitive Performance in Episodic and Chronic Migraine

European Journal of Neurology, Volume 33, Issue 4, April 2026.
Migraine is not only a pain disorder but a dynamic network disorder with measurable cognitive consequences. Interictally, working memory impairment was observed in episodic migraine, while chronic migraine showed broader deficits in attention and executive functions.
Esra Kochan Kizilkilic, Bekir Burak Kılboz, Serap Üçler Yaman   +2 more
wiley   +1 more source

Efficacy and Safety of Conventional and Biologic Therapies in Prurigo Nodularis: A Systematic Review and Meta‐Analysis

International Journal of Dermatology, Volume 65, Issue 4, Page 724-736, April 2026.
ABSTRACT Prurigo nodularis (PN) is a chronic, intensely pruritic skin disorder characterized by hyperkeratotic nodules and a debilitating itch–scratch cycle. Conventional therapies have limited efficacy and safety issues, while biologics have recently emerged as a promising alternative.
Andrea Lancz, Fanni Adél Meznerics, Renáta Árok, Anna Sára Lengyel, Bence Szabó, Péter Hegyi, Norbert Kiss, András Bánvölgyi   +7 more
wiley   +1 more source

Neuropeptides and the Autonomic Nervous System in Prader-Willi Syndrome. [PDF]

Int J Mol Sci
Höybye C, Petersson M.
europepmc   +1 more source