Results 41 to 50 of about 62,802 (169)

Phylogenetic investigation of peptide hormone and growth factor receptors in five dipteran genomes

Frontiers in Endocrinology, 2013
Peptide hormones and growth factors bind to membrane receptors and regulate a myriad of processes in insects and other metazoans. The evolutionary relationships among characterized and un-characterized (orphan) receptors can provide insights into ...
Kevin J. Vogel, Mark R Brown, Michael R Strand   +2 more
doaj   +1 more source

Neuropeptide Y receptor in the rat brain [PDF]

European Journal of Biochemistry, 1984
The specific binding of the chloramine-T iodinated neuropeptide Y (125I-NPY) to membranes from rat cerebral cortex was investigated using equilibrium binding and kinetic methods. The equilibrium binding of 125I-NPY at 37 degrees C was characterized by a Kd value of 0.38 nM. The receptor densities in the cerebral cortex, hypothalamus and cerebellum were
A, Undén, K, Tatemoto, V, Mutt, T, Bartfai   +3 more
openaire   +2 more sources

A Neuropeptide Courier for δ-Opioid Receptors? [PDF]

Cell, 2005
The delta-opioid receptor and the precursor protein of a neuropeptide, substance P, are colocalized in the large dense-core vesicles of pain-sensing neurons. In this issue of Cell, report that trafficking of the delta-opioid receptor to these vesicles depends on its physical interaction with the substance P domain of its precursor polyprotein ...
Julius, David, Basbaum, Allan I.
openaire   +2 more sources

Transcriptome-Wide Identification of Neuropeptides and Neuropeptide Receptors in the Twenty-Eight-Spotted Ladybird Henosepilachna vigintioctopunctata

Insects
The ladybird beetle, Henosepilachna vigintioctopunctata, is an oligophagous pest with significant economic impact. This pest causes considerable economic damage on numerous Solanaceae crops.
Quanxing Lei, Ziming Wang, Shuangyan Yao, Aili Lin, Yunhui Zhang, Chengxian Sun, Xiaoguang Liu, Mengfang Du, Xiaoming Liu, Shiheng An   +9 more
doaj   +1 more source

Neuropeptide Y receptors: How to get subtype selectivity

Frontiers in Endocrinology, 2013
The neuropeptide Y system is a multireceptor/multiligand system consisting of four receptors in humans (hY1, hY2, hY4, hY5) and three agonists (NPY, PYY, PP) that activate these receptors with different potency.
Xavier ePedragosa Badia, Jan eStichel, Annette G Beck-Sickinger   +2 more
doaj   +1 more source

Large-scale deorphanization of Nematostella vectensis neuropeptide G protein-coupled receptors supports the independent expansion of bilaterian and cnidarian peptidergic systems

eLife
Neuropeptides are ancient signaling molecules in animals but only few peptide receptors are known outside bilaterians. Cnidarians possess a large number of G protein-coupled receptors (GPCRs) – the most common receptors of bilaterian neuropeptides – but ...
Daniel Thiel, Luis Alfonso Yañez Guerra, Amanda Kieswetter, Alison G Cole, Liesbet Temmerman, Ulrich Technau, Gáspár Jékely   +6 more
doaj   +1 more source

Mechanisms involved in the regulation of neuropeptide-mediated neurite outgrowth: a minireview

Endocrine Regulations, 2016
The present knowledge, regarding the neuronal growth and neurite extension, includes neuropeptide action in the central nervous system. Research reports have brought much information about the multiple intracellular signaling pathways of neuropeptides ...
Lestanova Z., Bacova Z., Bakos Jan
doaj   +1 more source

Does kisspeptin belong to the proposed RF-amide peptide family?

Frontiers in Endocrinology, 2014
Kisspeptin (KISS) plays a key role in regulating reproduction by binding to its receptor, GPR54 (KISSR). Because of the Arg-Phe (RF) sequence at its carboxyl terminus, KISS has been proposed to be a member of the RF-amide peptide family consisting of ...
Seongsik eYun, Dong-Kyu eKim, Michael eFurlong, Jong-Ik eHwang, Hubert eVaudry, Jae Young eSeong   +5 more
doaj   +1 more source

Neuropeptides as regulators of bone metabolism: from molecular mechanisms to traditional Chinese medicine intervention strategies

Frontiers in Pharmacology
Osteoporosis (OP) is a complex bone metabolism disorder disease that affects the skeleton, nervous system, muscles, and multiple tissues. Neuropeptides, which are endogenous substances derived from both bone and brain, play a critical role in maintaining
Qing Lin, Qing Lin, Biyi Zhao, Jiajia Huang, Rumeng Chen, Weipeng Sun, Qianyun Ye, Qianyun Ye, Li Yang, Li Yang, Xiaofeng Zhu, Xiaofeng Zhu, Xiaofeng Zhu, Xiaoyun Li, Xiaoyun Li, Ronghua Zhang, Ronghua Zhang   +16 more
doaj   +1 more source

Fluorescent ligands for studying neuropeptide receptors by confocal microscopy

Brazilian Journal of Medical and Biological Research, 1998
This paper reviews the use of confocal microscopy as it pertains to the identification of G-protein coupled receptors and the study of their dynamic properties in cell cultures and in mammalian brain following their tagging with specific fluorescent ...
A. Beaudet, D. Nouel, T. Stroh, F. Vandenbulcke, C. Dal-Farra, J.-P. Vincent   +5 more
doaj   +1 more source