Results 101 to 110 of about 40,251 (303)

Neuropeptide Y receptors: a promising target for cancer imaging and therapy.

, 2015
Neuropeptide Y (NPY) was first identified from porcine brain in 1982, and plays its biological functions in humans through NPY receptors (Y1, Y2, Y4 and Y5).
Li, Juan, Wu, Aiguo, Tian, Yuchen
core  

Longitudinal Swallowing and Salivary Changes With CLR 131 and Re‐Irradiation in Recurrent Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Background Patients with recurrent head and neck cancer (HNC) often present with severe, persistent dysphagia and xerostomia following prior chemoradiation. Although swallowing impairments and salivary dysfunction have been reported in this population, prior longitudinal studies have not examined changes in salivary composition or how these ...
Jenni Wu, Sara Gustafson, Meredith Hyun, Roxana Alexandridis, Mark Nicosia, Timothy McCulloch, Justine Bruce, Randall Kimple, Nicole Rogus‐Pulia   +8 more
wiley   +1 more source

Hydrogel‐based drug delivery systems for intracerebral hemorrhage with therapeutic advances and emerging roles of the bone–brain axis

Interdisciplinary Medicine, EarlyView.
Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi, Min Chen, Yisheng Chen, MengYao Li, Jiale Ma, Zuozhen Yin, Li Wu, YangBao Miao, Zemin Ou, Ke Wu, Zhijie Xu, Lizhi Li, Shaocong Zhao, Shiwei He, Bin Huang, Guanwen He, Guanghui Wu, John H. Zhang, Liang Shi   +18 more
wiley   +1 more source

Interactions of GPR54 and GPR147 receptors with RF-amide ligands

, 2014
Includes bibliographical references.G protein-coupled receptors play a key role in cellular signaling by transducing extracellular signals via G proteins to elicit intracellular responses.
Hendrikse, Megan
core  

Delivery Routes and Anesthesia Affect Cord Blood NGF, BDNF, and Neonatal Outcomes

Journal of Clinical Laboratory Analysis, EarlyView.
Nerve growth factor (NGF) and brain‐derived neurotrophin (BDNF) play a role in brain maturation. Cord blood values do not differ between vaginal delivery and CS cases. In CS cases with spinal anesthesia, high BDNF and NGF values were associated with high cord blood pH and APGAR scores.
Şükran Doğru, Huriye Ezveci, Fikriye Karanfil Yaman, Pelin Bahçeci, Zeynep Şenol, İbrahim Kılınç, Kazım Gezginç   +6 more
wiley   +1 more source

Molecular mechanism of prolactin-releasing peptide recognition and signaling via its G protein-coupled receptor

Cell Discovery
Prolactin-releasing peptide (PrRP) is an RF-amide neuropeptide that binds and activates its cognate G protein-coupled receptor, prolactin-releasing peptide receptor (PrRPR), also known as GPR10.
Yang Li, Qingning Yuan, Xinheng He, Yumu Zhang, Chongzhao You, Canrong Wu, Jingru Li, H. Eric Xu, Li-Hua Zhao   +8 more
doaj   +1 more source

O neuropeptídio Y (NPY) na medula espinhal medeia o efeito hiponociceptivo da ativação de receptores H1 histaminérgicos na articulação do joelho de ratos [PDF]

, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2013.A histamina é encontrada no líquido sinovial de indivíduos saudáveis e pacientes com diversos tipos ...
Silva, Eduardo Souza
core  

Neuropeptide Y in sympathetic co-transmission: recent advances in the search for neuropeptide Y antagonists

, 1994
Since the discovery of neuropeptide Y which is co-stored and co-operate with noradrenaline (NA) in sympathetic nerve fibers, several scientific groups have searched for structures with neuropeptide Y antagonistic properties.
Edvinsson, Lars, Hedner, T, David Erlinge, Erlinge, David, Sun, X Y, Lars Edvinsson, Xiang Ying Sun, Thomas Hedner   +7 more
core   +1 more source

Psychodermatology of the Female: Hormones, Skin and Mental Health Across the Lifespan

JEADV Clinical Practice, EarlyView.
Hormonal transitions across the female lifespan shape skin disease and psychiatric comorbidity through the brain–skin axis and Neuro‐Immuno‐Cutaneous‐Endocrine (NICE) network. This narrative review links puberty, menstruation, pregnancy, postpartum and menopause to dermatologic and psychosocial outcomes.
Sheila Sharifi, Jessica Gulati, Veranca Shah, Keira Barr, Mohammad Jafferany   +4 more
wiley   +1 more source

Neuropeptide Y modulates the electrical activity of subfornical organ neurons

Current Research in Neurobiology
The subfornical organ (SFO) is a sensory circumventricular organ, lacking a blood-brain barrier. It is well-recognized as a key center for detection and integration of osmotic, ionic and hormonal signals for maintenance of hydromineral balance and ...
Lauren Shute, Mark Fry
doaj   +1 more source