Results 171 to 180 of about 27,803 (242)

Exploring neuronal mechanisms of osteosarcopenia in older adults

The Journal of Physiology, EarlyView.
Abstract figure legend The mechanosensitive osteocytic network within the bone matrix acts as a receptor and plays a crucial role in the functional adaptation of bone to mechanical loading. Through mechanotransduction, osteocytes convert mechanical impulses into electrical signals, which are transmitted via afferent nerves to sympathetic preganglionic ...
Ilhan Karacan, Kemal Sıtkı Türker
wiley   +1 more source

DAMPs cross-talk interpretation of MDD mechanisms. [PDF]

Sci Adv
Peng Y, Chen Z, Xu Y, Ren B.
europepmc   +1 more source

Somatostatin modulation of initial fusion pores in Ca2+‐triggered exocytosis from mouse chromaffin cells

The Journal of Physiology, EarlyView.
Abstract figure legend Somatostatin binds to a G‐protein‐coupled receptor to inhibit the release of catecholamine from chromaffin cells. This action has no impact on Ca2+ levels and is similar for Ca2+ entry through voltage‐gated Ca2 channels and for Ca2+ mobilization from the endoplasmic reticulum.
Jinbo Cheng, Meyer B. Jackson
wiley   +1 more source

Antimicrobial Neuropeptides and Their Receptors: Immunoregulator and Therapeutic Targets for Immune Disorders. [PDF]

Molecules
Chen K, Wu X, Li X, Pan H, Zhang W, Shang J, Di Y, Liu R, Zheng Z, Hou X.   +9 more
europepmc   +1 more source

Incretin hormones and obesity

The Journal of Physiology, EarlyView.
Abstract figure legend The incretin system in obesity. The incretin hormones glucose‐dependent insulinotropic polypeptide (GIP) (yellow) and glucagon‐like peptide‐1 (GLP‐1) (blue) are produced by the proximal and distal small intestinal epithelium, where they are released postprandially into the bloodstream to modulate a myriad of physiological and ...
Constanza Alcaino, Frank Reimann, Fiona M. Gribble   +2 more
wiley   +1 more source

Neuropeptides: The Evergreen Jack-of-All-Trades in Neuronal Circuit Development and Regulation. [PDF]

Bioessays
Hevesi Z, Hökfelt T, Harkany T.
europepmc   +1 more source

Activation of TRPA1 and TRPM3 triggers Ca2+ waves in central terminals of sensory neurons and facilitates synaptic activity in the spinal dorsal horn

The Journal of Physiology, EarlyView.
Abstract figure legend Transient receptor potential ankyrin 1 (TRPA1) and melastatin 3 (TRPM3) activation regulate pre‐ and postsynaptic Ca2+ concentrations and synaptic activity in the dorsal horn of the spinal cord. Left: a model that describes how activation of TRPA1 and TRPM3 channels induces an influx of Ca2+ in the central terminals of sensory ...
Yaroslav E. Andrianov, Alex L. Keyes, Charles A. Warwick, Miriam C. McDonough, Leonid P. Shutov, Kavita S. Solanki, Jon M. Resch, Alexander G. Bassuk, Nana Voitenko, Pavel Belan, Yuriy M. Usachev   +10 more
wiley   +1 more source

Neural influences in colorectal cancer progression and therapeutic strategies. [PDF]

Int J Colorectal Dis
Zeng Z, Cai S, Ye C, Li T, Tian Y, Liu E, Cai J, Yuan X, Yang H, Liang Q, Li K, Peng C.   +11 more
europepmc   +1 more source

Recent optical approaches for anatomical and functional dissection of neuron–astrocyte circuitry

The Journal of Physiology, EarlyView.
Abstract figure legend This review summarises novel optical approaches to deciphering structural and functional wiring diagrams of neuron–astrocyte circuits in the brain. There are three groups: the anatomical proximity assay, transsynaptic viral tracing and the functional connection assay. The FRET‐based neuron–astrocyte proximity assay allows mapping
Yoshiki Hatashita, Takafumi Inoue
wiley   +1 more source

Electroacupuncture stimulation induced M1/M2 polarization in white adipose tissues by activating the Y1 receptor in obese mice to reduce chronic inflammation. [PDF]

Adipocyte
Lu M, Yu Z, Yang X, Yang Z, Xu T, Yu Z, Jing X, An L, Zhang J, Xu B.   +9 more
europepmc   +1 more source