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GLP-1 and GIP Beyond Glycaemia: Evolutionary Roles in Energy Optimisation and Organ Protection. [PDF]
Tuccinardi D +5 more
europepmc +1 more source
Transcriptional regulation of neuropeptide receptors underlies context-dependent adaptation in Drosophila melanogaster. [PDF]
Ryu S +6 more
europepmc +1 more source
Sympathovagal crosstalk: Y2-receptor blockade enhances vagal effects which in turn reduce NPY levels via muscarinic receptor activation. [PDF]
Jani NR +12 more
europepmc +1 more source
Heartfelt intervention: A role for PVN oxytocin neurons in the prediabetic heart
The Journal of Physiology, EarlyView.
Grace K. Nielsen +2 more
wiley +1 more source
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Neuropeptide Y receptor subtypes
Life Sciences, 1995Neuropeptide Y (NPY) is an amidated 36-amino acid peptide with a wide distribution in the central and peripheral nervous system. It can evoke numerous physiological responses by activating specific receptors. Studies using NPY analogs in various model systems and cell types demonstrate different orders of ligand potency and receptor binding affinity ...
C P, Wan, B H, Lau
openaire +2 more sources
Dihydropyridine Neuropeptide Y Y1 Receptor Antagonists
Bioorganic & Medicinal Chemistry Letters, 2002Dihydropyridine 5a was found to be an inhibitor of neuropeptide Y(1) binding in a high throughput (125)I-PYY screening assay. Structure-activity studies around certain portions of the dihydropyridine chemotype identified BMS-193885 (6e) as a potent and selective Y(1) receptor antagonist.
Graham S, Poindexter +13 more
openaire +2 more sources

