Results 21 to 30 of about 204,197 (323)

Synthesis of receptor antagonists of neuropeptide Y. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1992
We report the synthesis of receptor antagonists of neuropeptide Y (NPY) by a strategy based on synthesis of mixtures of analogs and the subsequent isolation and identification of receptor antagonists from these mixtures. After screening a series of mixtures of NPY analogs by using an NPY antagonist assay, two potent receptor antagonists, designated PYX-
Meikyo Shimizu   +2 more
openaire   +3 more sources

A companion to the preclinical common data elements and case report forms for neuropathology studies in epilepsy research. A report of the TASK3 WG2 Neuropathology Working Group of the ILAE/AES Joint Translational Task Force

open access: yesEpilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica   +6 more
wiley   +1 more source

Neuropeptide System Regulation of Prefrontal Cortex Circuitry: Implications for Neuropsychiatric Disorders

open access: yesFrontiers in Neural Circuits, 2022
Neuropeptides, a diverse class of signaling molecules in the nervous system, modulate various biological effects including membrane excitability, synaptic transmission and synaptogenesis, gene expression, and glial cell architecture and function. To date,
Sanne M. Casello   +9 more
doaj   +1 more source

NPY1R (neuropeptide Y receptor Y1) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on NPY1R (neuropeptide Y receptor Y1), with data on DNA, on the protein encoded, and where the gene is implicated.
M. Ruscica   +3 more
openaire   +4 more sources

Neuropeptide Y Is an Immunomodulatory Factor: Direct and Indirect

open access: yesFrontiers in Immunology, 2020
Neuropeptide Y (NPY), which is widely distributed in the nervous system, is involved in regulating a variety of biological processes, including food intake, energy metabolism, and emotional expression.
Wei-can Chen   +5 more
semanticscholar   +1 more source

Platelet lysate-derived neuropeptide y influences migration and angiogenesis of human adipose tissue-derived stromal cells [PDF]

open access: yes, 2018
Neuropeptide Y (NPY), a powerful neurotransmitter of the central nervous system, is a key regulator of angiogenesis and biology of adipose depots. Intriguingly, its peripheral vascular and angiogenic powerful activity is strictly associated to platelets,
Bordin, Antonella   +13 more
core   +2 more sources

Identification of neuropeptides and neuropeptide receptor genes in Phauda flammans (Walker)

open access: yesScientific Reports, 2022
Neuropeptides and neuropeptide receptors are crucial regulators to insect physiological processes. The 21.0 Gb bases were obtained from Illumina sequencing of two libraries representing the female and male heads of Phauda flammans (Walker) (Lepidoptera ...
Hai-Pan Wu   +5 more
doaj   +1 more source

Y1 and Y2 receptors for neuropeptide Y [PDF]

open access: yesFEBS Letters, 1989
By using monoiodinated radioligands of both intact neuropeptide Y (NPY) and of a long C‐terminal fragment, NPY13–36, two subtypes of binding sites, which differ in affinity and specificity, have been characterized. The Y1 type of binding site, characterized on a human neuroblastoma cell line, MC‐IXC, and a rat pheochromocytoma cell line, PC‐12, binds ...
Thue W. Schwartz   +2 more
openaire   +3 more sources

A tool kit of highly selective and sensitive genetically encoded neuropeptide sensors

open access: yesScience, 2023
Neuropeptides are key signaling molecules in the endocrine and nervous systems that regulate many critical physiological processes. Understanding the functions of neuropeptides in vivo requires the ability to monitor their dynamics with high specificity,
Huan Wang   +27 more
semanticscholar   +1 more source

The neuropeptide transcriptome of a model echinoderm, the sea urchin Strongylocentrotus purpuratus [PDF]

open access: yes, 2012
The work reported here was supported by a grant from the University of London Central Research ...
Elphick, MR, Rowe, ML
core   +1 more source

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