Results 161 to 170 of about 115,139 (216)
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Neurotransmitter receptors as glycoproteins
Experientia, 1983Incubation of calf brain membrane preparations with the plant lectins, concanavalin A and wheat germ agglutinin did not inhibit neurotransmitter receptor binding sites directly. Plant lectins did however protect these sites against subsequent trypsin digestion suggesting that neurotransmitter binding sites may be associated with glycoprotein structures.
T. J. Crow, J. A. Johnson, Alan J. Cross
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Neurotransmitter receptors on microglia
Trends in Neurosciences, 2007Microglia are the intrinsic immune cells of the brain and express chemokine and cytokine receptors that interact with the peripheral immune cells. Recent studies have indicated that microglia also respond to the brain's classical signalling substances, the neurotransmitters.
Helmut Kettenmann, Jennifer M. Pocock
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Immunocytochemistry of neurotransmitter receptors
Journal of Electron Microscopy Technique, 1990AbstractOver the last several years our knowledge of neurotransmitter receptors has increased dramatically as receptor types and subtypes have been identified through the development of selective antagonists, neuropharmacological studies, and radioactive ligand binding studies.
Richard A. Altschuler +2 more
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The Cytoskeleton and Neurotransmitter Receptors
1996The neuronal cytoskeleton consists of microtubules and microfilaments that can interact with membrane proteins including neurotransmitter receptors and ion channels. Ligand-gated ion channels, such as nicotinic acetylcholine receptors, glycine receptors, glutamate receptors and gamma-aminobutryic acidA (GABAA) receptors, are known to cluster in plasma ...
Valerie J. Whatley, R A Harris
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Neurotransmitter Receptors and Aging
Journal of the American Geriatrics Society, 1984The role of receptors in the central nervous system and effects of aging on the four neurotransmitter receptors most often studied in the context of aging—beta‐adrenergic, cholinergic, benzodiazepine, and dopamine—are discussed.
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Quantitative densitometry of neurotransmitter receptors
Journal of Neuroscience Methods, 1982An autoradiographic procedure is described that allows the quantitative measurement of neurotransmitter receptors by optical density readings. This procedure is a modification of the method of Young and Kuhar (1979a). Frozen brain sections are labeled in vitro with [3H]ligands under conditions that maximize specific binding to neurotransmitter ...
Bruce S. McEwen +3 more
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2010
Neurotransmitter receptors play a vital role in the normal functioning of the nervous system. Controlled modulation of neurotransmitter receptors is critical for proper signaling between nerve cells and effector organs. Factors that disrupt normal neurotransmitter signaling can alter the homeostasis of the cells or tissues, leading to adverse effects ...
Vishnu Suppiramaniam +2 more
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Neurotransmitter receptors play a vital role in the normal functioning of the nervous system. Controlled modulation of neurotransmitter receptors is critical for proper signaling between nerve cells and effector organs. Factors that disrupt normal neurotransmitter signaling can alter the homeostasis of the cells or tissues, leading to adverse effects ...
Vishnu Suppiramaniam +2 more
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Neurotransmitter Receptors And Phosphoinositide Turnover
Annual Review of Pharmacology and Toxicology, 1989Neurotransmitters, neuromodulators, hormones and growth-promoting fac tors are now known to exhibit their diverse metabolic and physiological responses by interaction with their selective receptors located on the cell surface. These surface receptors transduce and amplify extracellular signals by the generation of so-called second messengers.
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Neurotransmitter receptors as targets for pesticides
Journal of Environmental Science and Health, Part B, 1983Nicotinic and muscarinic acetylcholine (ACh) receptors have been identified biochemically by means of their specific binding of [3H] alpha-bungarotoxin ([3H]alpha-BGT) and [3H]quinuclidinyl benzilate, respectively. There are some differences in the drug specificities, and sensitivities to active group reagents, of these receptors in insects when ...
Mohyee E. Eldefrawi, Amira T. Eldefrawi
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2004
Chemical transmission is the fundamental mode of communication in the nervous system that depends on receptors in the plasma membrane for sensing released neurotransmitter and for producing an appropriate, well-timed response. Two distinct types of receptors mediate this process: ionotropic and G-protein coupled.
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Chemical transmission is the fundamental mode of communication in the nervous system that depends on receptors in the plasma membrane for sensing released neurotransmitter and for producing an appropriate, well-timed response. Two distinct types of receptors mediate this process: ionotropic and G-protein coupled.
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