Molecular Physiology of the Neuronal Synapse. [PDF]
Ramírez-Expósito MJ +2 more
europepmc +1 more source
Decreased BOLD Signal Variability in Middle‐Aged and Older Adults on the Autism Spectrum
ABSTRACT Autism spectrum disorder (ASD) is a lifelong neurodevelopmental disorder. Preliminary evidence suggests an increased risk for early‐onset cognitive and neurological decline in ASD. While brain development in children, adolescents, and young adults with ASD diverges from neurotypical (NT) peers, it remains unclear in older adults with ASD ...
Stephanie Pedrahita +9 more
wiley +1 more source
Enteric nervous system and inflammatory bowel disease. [PDF]
Wang S +6 more
europepmc +1 more source
Interval Timing Is Altered in Male Nrxn1+/− Mice: A Model of Autism Spectrum Disorder
ABSTRACT Autism spectrum disorder (ASD) is characterized by impaired social interactions and communication, and increased repetitive and stereotypical behavior. Neuroimaging shows functional abnormalities in brain areas involved in temporal processing in autistic individuals, and they also show deficits in interval timing.
Kyle M. Roddick +3 more
wiley +1 more source
Olfactory inputs to appetite neurons in the hypothalamus. [PDF]
Kuang D +9 more
europepmc +1 more source
The 3‐Hit Metabolic Signaling Model for Autism Spectrum Disorder: A Summary
ABSTRACT Autism spectrum disorder (ASD) is a highly heritable yet environmentally sensitive neurodevelopmental condition whose biological heterogeneity has resisted a unifying causal explanation for over 100 years. The 3‐hit metabolic signaling model proposes that ASD arises from abnormal persistence of an evolutionarily conserved stress‐response ...
Robert K. Naviaux
wiley +1 more source
Multimodal neuroimaging reveals brain neurochemical disturbances associated with superoxide dismutase in first-episode drug-naïve schizophrenia. [PDF]
Zhu Z +8 more
europepmc +1 more source
The E3 Ubiquitin Ligase UBE3B Regulates Synaptic Development and Cortical Network Activity
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired communication, abnormal social interactions, and restricted, repetitive behaviors. Pathogenic mutations in UBE3B result in neurodevelopmental disease, including intellectual disability, lack of speech, and ASD.
Shayal Vashisth +7 more
wiley +1 more source
Molecular and Transcriptional Signatures of Gray Matter Volume Alterations Associated With Depressive Symptoms in Mild Cognitive Impairment. [PDF]
Xu H +9 more
europepmc +1 more source
ABSTRACT The etiopathogenesis of Autism Spectrum Disorder (ASD) encompasses complex interactions between genetic and environmental risk factors. The high prevalence of gastrointestinal disorders in autistic individuals has propelled a growing interest in the possible involvement of gut dysbiosis in ASD pathogenesis.
Laura Sandoni +6 more
wiley +1 more source

