Role of endogenous acetylcholine in the control of the dopaminergic system via nicotinic receptors.
International audienceNicotinic acetylcholine receptors (nAChRs) are pentameric membrane protein receptors activated by the addictive drug, nicotine.
Maskos, Uwe, Uwe Maskos
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The lipid habitats of neurotransmitter receptors in brain [PDF]
Neurotransmitter receptors, the macromolecules specialized in decoding the chemical signals encrypted in the chemical signaling mechanism in the nervous system, occur either at the somatic cell surface of chemically excitable cells or at specialized ...
Valles, Ana Sofia +2 more
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Autoantibodies to Neurotransmitter Receptors and Ion Channels in Psychotic Disorders
Cell surface antibody–associated central nervous system disorders have emerged in the last decade as a novel field in neuroimmunology. It is now well known that patients with antibodies to ion channels such as N-methyl-D-aspartate receptor and voltage ...
Erdem Tuzun
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Neurochemical Changes in the Mouse Hippocampus Underlying the Antidepressant Effect of Genetic Deletion of P2X7 Receptors. [PDF]
Recent investigations have revealed that the genetic deletion of P2X7 receptors (P2rx7) results in an antidepressant phenotype in mice. However, the link between the deficiency of P2rx7 and changes in behavior has not yet been explored.
Zsilla Gabriella +29 more
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GABA potency at GABAA receptors found in synaptic and extrasynaptic zones
The potency of GABA is vitally important for its primary role in activating GABAA receptors and acting as an inhibitory neurotransmitter. Although numerous laboratories have presented information, directly or indirectly, on GABA potency, it is often ...
Martin eMortensen +2 more
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CRELD1 is an evolutionarily-conserved maturational enhancer of ionotropic acetylcholine receptors
The assembly of neurotransmitter receptors in the endoplasmic reticulum limits the number of receptors delivered to the plasma membrane, ultimately controlling neurotransmitter sensitivity and synaptic transfer function.
Manuela D'Alessandro +6 more
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GABAA receptors: post-synaptic co-localization and cross-talk with other receptors
γ-aminobutyric acid type A receptors (GABAARs) are the major inhibitory neurotransmitter receptors in the central nervous system (CNS), and importantly contribute to the functional regulation of the nervous system. Several studies in the last few decades
Amulya Nidhi Shrivastava +3 more
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Endoplasmic reticulum sorting and kinesin-1 command the targeting of axonal GABAB receptors. [PDF]
In neuronal cells the intracellular trafficking machinery controls the availability of neurotransmitter receptors at the plasma membrane, which is a critical determinant of synaptic strength.
Viviana Valdés +7 more
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Environmental enrichment and neurotransmitter receptors [PDF]
The extent of high affinity, specific binding of several pharmacological agents to brain membrane fractions derived from rats reared in an environmentally enriched or impoverished environment has been assayed. The binding of all labeled agents studied was not significantly altered in cerebellar, subcortical, or cortical membranes by the rearing ...
Por, SB, Bennett, EL, Bondy, SC
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Effects of ethylenediamine – a putative GABA-releasing agent – on rat hippocampal slices and neocortical activity in vivo [PDF]
The simple diamine diaminoethane (ethylenediamine, EDA) has been shown to activate GABA receptors in the central and peripheral nervous systems, partly by a direct action and partly by releasing endogenous GABA.
Lui, C., Stone, T.W., Addae, J.I.
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