Results 71 to 80 of about 214,427 (207)
Pathophysiological role of extrasynaptic GABAA receptors in typical absence epilepsy [PDF]
, 2011 GABA is the principal inhibitory neurotransmitter in the mammalian CNS. It acts via two classes of receptors, the GABAA, a ligand gated ion channel (ionotropic receptor) and the metabotropic G-protein coupled GABAB receptor.
Errington, Adam C. +2 more
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Subunit Composition of Neurotransmitter Receptors in the Immature and in the Epileptic Brain [PDF]
, 2014 Neuronal activity is critical for synaptogenesis and the development of neuronal networks. In the immature brain excitation predominates over inhibition facilitating the development of normal brain circuits, but also rendering it more susceptible to ...
Loddenkemper, Tobias +1 more
core +1 more source
Adenosine Receptor Heteromers and their Integrative Role in Striatal Function
The Scientific World Journal, 2007 By analyzing the functional role of adenosine receptor heteromers, we review a series of new concepts that should modify our classical views of neurotransmission in the central nervous system (CNS).
Sergi Ferré +10 more
doaj +1 more source
GABA_{B} Receptors Regulate Chick Retinal Calcium Waves
, 2001 Correlated spiking activity and associated Ca²⁺ waves in the developing retina are important in determining the connectivity of the visual system. Here, we show that GABA, via GABA_{B} receptors, regulates the temporal characteristics of Ca²⁺ waves ...
Catsicas, M, Mobbs, P
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A toolkit for orthogonal and in vivo optical manipulationof ionotropic glutamate receptors
Frontiers in Molecular Neuroscience, 2016 The ability to optically manipulate specific neuronal signaling proteins with genetic precision paves the way for the dissection of their roles in brain function, behavior, and disease.
Joshua Todd Levitz +3 more
doaj +1 more source
, 2003 A reduction in microglial activation and subsequent neurotoxicity may prove critical for neuroprotection in neurodegenerative diseases. We examined the expression and functionality of group III metabotropic glutamate (mGlu) receptors on microglia.
Taylor, D.L., Pocock, J.M., Diemel, L.T.
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i-Perception, 2011 In the primary visual cortex, activity of neurons evoked by stimuli within the classical receptive field (CRF) can be modulated by stimuli in the extra-receptive field (ERF).
Xue-Mei Song, Yu Yin, Chao-Yi Li
doaj +1 more source
Neurotransmitter receptors in the life and death of oligodendrocytes
, 2007 Oligodendrocytes are crucial to the function of the mammalian brain: they increase the action potential conduction speed for a given axon diameter and thus facilitate the rapid flow of information between different brain areas.
Attwell, D. +3 more
core +1 more source
Ubiquitination of neurotransmitter receptors and postsynaptic scaffolding proteins
, 2020 The human brain is made up of an extensive network of neurons that communicate by forming specialized connections called synapses. The amount, location, and dynamic turnover of synaptic proteins, including neurotransmitter receptors and synaptic ...
Amy W Lin, Heng-Ye Man
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Heteromerización de receptores de adenosina A2A, dopamina D2 y cannabinoides CB1. Implicaciones farmacológicas y funcionales. [PDF]
, 2007 [spa] La visión de los receptores acoplados a proteína G ha evolucionado en los últimos años. Clásicamente se consideraban unidades individuales capaces de producir una señal intracelular; actualmente, está aceptado que estas proteínas de membrana pueden
Carriba Domínguez, Paulina
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