Results 161 to 170 of about 2,915 (172)
British Journal of Clinical Psychology, EarlyView.Abstract Background Medication non‐adherence is a leading cause of treatment failure in psychiatric populations. However, current studies highlight the lack of methodological guidance on medication assessments. Ecological Momentary Assessment (EMA), using smartphone‐based evaluations, shows promise for real‐time monitoring in everyday settings.
Valentine Chirokoff +8 more
wiley +1 more source
Brain Pathology, EarlyView.Elevated angiogenin levels in skeletal muscle are linked to slower disease progression, enhanced regeneration, and vascularization through satellite‐endothelial interaction during myogenesis in ALS. Angiogenin and its tiRNAs may serve as prognostic markers and therapeutic targets for ALS.
Paola Fabbrizio +13 more
wiley +1 more source
G protein‐coupled receptor‐mediated autophagy in health and disease
British Journal of Pharmacology, EarlyView.G protein‐coupled receptors (GPCRs) constitute the largest and most diverse superfamily of mammalian transmembrane proteins. These receptors are involved in a wide range of physiological functions and are targets for more than a third of available drugs in the market. Autophagy is a cellular process involved in degrading damaged proteins and organelles
Devrim Öz‐Arslan +2 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with limited treatment options. ALS pathogenesis involves intricate processes within motor neurons, characterized by dysregulated Ca2+ influx and buffering in early ALS‐affected motor neurones. This study proposes the modulation of ryanodine receptors (
Laura Moreno‐Martinez +17 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Hyoscine butylbromide (HBB) has a low oral (PO) bioavailability. Further, limited data on its activity on non‐gastrointestinal (GI) smooth muscle spasms after oral dosing are available, causing its effects beyond the GI tract to be questioned.
Sara Traserra +4 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Preclinical studies suggest that highly selective dopamine D3 receptor (D3R) antagonists or partial agonists hold promise for treating substance use disorders. However, their limited effectiveness in reducing cocaine self‐administration is a major drawback.
Omar Soler‐Cedeño +9 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Platelet function during inflammation is dependent on activation by endogenous nucleotides acting on purinergic receptors. The P2Y14 receptor has been reported to be expressed on platelets and is involved in leukocyte recruitment during inflammation.
Md Monir Hossain +6 more
wiley +1 more source
Child &Family Social Work, EarlyView.ABSTRACT In Sweden, both maltreatment and behavioural problems are indicative of needs that motivate interventions from child welfare services (CWS). However, the likelihood of being referred to CWS can be influenced by other than indicative factors on individual, peer and school‐area levels.
Torbjörn Kalin
wiley +1 more source
Contact Urticaria and Related Conditions: Clinical Review
Contact Dermatitis, EarlyView.ABSTRACT Contact urticaria (CoU) is an immediate contact reaction occurring within minutes to an hour after exposure to specific proteins or chemicals. CoU is categorised into non‐immunologic (NI‐CoU) and immunologic (I‐CoU) types, with I‐CoU potentially leading to anaphylaxis. Both forms of CoU can be associated with protein contact dermatitis and the
Mojca Bizjak +15 more
wiley +1 more source
Cell Proliferation, EarlyView.Polymeric nanoparticles represent promising drug (gene) delivery carriers to the brain due to their unique advantages to facilitate the penetration of blood–brain barrier and endocytosis of neuronal cells in neurodegenerative diseases. ABSTRACT In spite of great advances in modern medicine, there are a few effective strategies for the treatment of ...
Lian Jin +4 more
wiley +1 more source