Results 161 to 170 of about 2,466,892 (329)

Mammalian nicotinic acetylcholine receptors: from structure to function.

Physiological Reviews, 2009
E. Albuquerque, E. Pereira, M. Alkondon, S. Rogers   +3 more
semanticscholar   +1 more source

Weizmannia coagulans XY2 Mitigates Copper Neurotoxicity via Gut–Brain Axis Modulation of Tryptophan Metabolism and Oxidative‐Inflammatory Crosstalk

iMetaOmics, EarlyView.
Copper interferes with tryptophan metabolism and 5‐HT levels by modulating intestinal flora. Intestinal barrier breakdown and inflammatory response trigger nerve damage under copper exposure. W. coagulans XY2 alleviates copper‐induced neurotoxicity by targeting a multi‐dimensional “tryptophan metabolism‐antioxidant defense‐gut‐brain axis” network.
Yufang Gao, Xiaodong Zheng, Fujie Yan
wiley   +1 more source

Evaluation of Acute Exposure to Combustible and Novel Tobacco Products Using an In Vitro Human Airway Organ Tissue Equivalent Model

Journal of Applied Toxicology, EarlyView.
ABSTRACT Despite the well‐known risks of tobacco use, tobacco exposure remains a major contributor to morbidity and mortality worldwide. Although cigarette use has declined, the popularity of novel tobacco products (NTPs), such as electronic cigarettes (ECs) and heated tobacco products (HTPs), has increased.
Timothy S. Leach, Steven Albertson, Phillip W. Clapp, Vikram Surendran, Trang Simon, Eric C. Donny, Stephen J. Walker, Anthony Atala, Sean V. Murphy   +8 more
wiley   +1 more source

Prognostic Factors for Complications Following Ultrasound‐Guided Percutaneous Kidney Biopsy: A 7‐Year Retrospective Study

Journal of Clinical Ultrasound, EarlyView.
Complications were common but mostly minor following ultrasound‐guided percutaneous kidney biopsy. Older age, obesity, and smoking were independently associated with a reduced risk of complications, including hematoma. These findings highlight the overall safety of the procedure and support individualized risk assessment based on patient ...
Sehyun Jung, Seunghye Lee, Hyejin Jeon, Hani Jang, Se‐Ho Chang, Hyun‐Jung Kim   +5 more
wiley   +1 more source

Nicotinic ACh receptors as therapeutic targets in CNS disorders.

TIPS - Trends in Pharmacological Sciences, 2015
K. Dineley, Anshul A. Pandya, J. Yakel
semanticscholar   +1 more source

Stress Management for Students in Dental Education: a Scoping Review

Journal of Dental Education, EarlyView.
ABSTRACT Stress in the university setting is well‐reported. This scoping review aims to synthesize and evaluate the current literature on stress in dental education to understand stress and stress‐management interventions that have been trialed with dental students.
Gillian D. Boehm, Jessica R. L. Lieffers, Sheryl Mills, Amrinderbir Singh   +3 more
wiley   +1 more source

Acetylcholine excites neocortical pyramidal neurons via nicotinic receptors.

Journal of Neurophysiology, 2015
T. Hedrick, Jack Waters
semanticscholar   +1 more source

Pharmacological MRI: Utility in Understanding Drug Mechanisms in Psychiatric Disorders

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Pharmacological MRI (pharmaMRI) has emerged as a powerful tool to study how psychoactive drugs affect brain function and to uncover mechanisms of drug action in psychiatric disorders. This review provides an overview of key techniques used in pharmaMRI, including BOLD‐fMRI, arterial spin labeling (ASL), and cerebral blood volume (CBV) mapping,
Christin Y. Sander, Tudor M. Ionescu, Mitul A. Mehta, Ottavia Dipasquale, Anouk Schrantee   +4 more
wiley   +1 more source

The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors

Science Translational Medicine, 2015
J. S. Wieskopf, Jayanti Mathur, W. Limapichat, Michael R. Post, M. Alqazzaz, R. Sorge, Loren J. Martin, D. Zaykin, Shad B. Smith, K. Freitas, J. Austin, F. Dai, Jie Zhang, Jaclyn Marcovitz, A. H. Tuttle, P. Slepian, Sarah E Clarke, R. Drenan, Jeff Janes, Sh. Al Sharari, S. Segall, E. Aasvang, Wei-Shan Lai, R. Bittner, Christopher I. Richards, G. Slade, H. Kehlet, J. Walker, U. Maskos, J. Changeux, M. Devor, W. Maixner, L. Diatchenko, L. Diatchenko, I. Belfer, D. Dougherty, A. Su, S. Lummis, M. Damaj, H. Lester, A. Patapoutian, J. Mogil   +41 more
semanticscholar   +1 more source

Effect of smoking over one pack daily on implant healing and health: A cohort study

Journal of Periodontology, EarlyView.
Abstract Background This prospective cohort trial examines the effects of heavy smoking on peri‐implant marginal bone loss (MBL) and implant survival rates over 15 months. Methods Thirty subjects, categorized as either smokers (more than 20 cigarettes daily for over 5 years) or non‐smokers, were initially recruited with pocket depths ≤ 5 mm and at ...
Yaniv Mayer, Eran Gabay, Eli E. Machtei, Eli Regev, Ofir Ginesin, Zvi Gutmacher, Jacob Horwitz, Luigi Canullo, Jamil Awad Shibli, Hadar Giladi Zigdon   +9 more
wiley   +1 more source