Results 171 to 180 of about 2,394,761 (293)

Internalizing symptoms are indirectly associated with simultaneous alcohol and cannabis use through specific motives for simultaneous use: A longitudinal study of young adults

Alcohol, Clinical and Experimental Research, EarlyView.
This longitudinal study found that when young adults experienced elevations in depression, anxiety and stress symptoms, they tended to report increased motivation to use cannabis and alcohol simultaneously. Motivations related to achieving positive subjective effects, in turn, predicted increased frequency of using cannabis during heavy drinking ...
Jeffrey D. Wardell, Kyra N. Farrelly, Annabelle Moore, Nicolle Fox, Sophie G. Coelho, John A. Cunningham, Roisin M. O'Connor, Christian S. Hendershot   +7 more
wiley   +1 more source

Investigating Therapeutic Targets for Alcohol Use Disorder: Pharmacological View of ClinicalTrials.gov Data. [PDF]

Int J Gen Med
Alorfi NM.
europepmc   +1 more source

Pharmacological and Mechanistic Interventions for Cognitive Impairment Associated With Schizophrenia: A Review of Registered Clinical Trials

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Schizophrenia is characterized by positive, negative, and cognitive symptoms. Current pharmacological treatments often fail to address cognitive deficits. In this review of clinical trials, we aim to identify studies that explore neurobiological (non‐psychological) strategies to address Cognitive Impairment Associated with ...
Bahareh Peyrovian, Lena Palaniyappan, Theodore T. Kolivakis, Howard C. Margolese   +3 more
wiley   +1 more source

Functional deletion of α7 nicotinic acetylcholine receptor impairs Ca²⁺-dependent glutamatergic synaptic transmission by affecting both presynaptic and postsynaptic protein expression and function. [PDF]

Front Physiol
Cannata B, Sposito L, Albini M, Aceto G, Puliatti G, Lazzarino G, Ripoli C, Tropea MR, Puzzo D, Piacentini R, Grassi C.   +10 more
europepmc   +1 more source

α4β2 Nicotinic Acetylcholine Receptors on Dopaminergic Neurons Mediate Nicotine Reward and Anxiety Relief

Journal of Neuroscience, 2011
Tresa M. McGranahan, Natalie E. Patzlaff, S. Grady, S. Heinemann, T. K. Booker   +4 more
semanticscholar   +1 more source

Trends and patterns of dual use of combustible tobacco and e‐cigarettes among adults in England: A population study, 2016–2024

Addiction, Volume 120, Issue 4, Page 608-619, April 2025.
Abstract Background/Aims E‐cigarettes are frequently used by people who smoke. This study measured how the prevalence and patterns of smoking and vaping (‘dual use’) in England have changed as the vaping market has rapidly evolved. Design Representative monthly cross‐sectional survey, July 2016 to April 2024. Setting England.
Sarah E. Jackson, Sharon Cox, Lion Shahab, Jamie Brown   +3 more
wiley   +1 more source

Molecular insights into the α6β4 nicotinic acetylcholine receptor function and ligand recognition. [PDF]

Nat Commun
Su J, Yu Z, Yin Z, Zhang Z, Zhao J, Meng Y, Li R, Gao Y, Zhang H, Yu R, Zhao Y.   +10 more
europepmc   +1 more source

An update of a systematic review and meta‐analyses exploring flavours in intervention studies of e‐cigarettes for smoking cessation

Addiction, Volume 120, Issue 4, Page 770-778, April 2025.
Abstract Aims To determine patterns of e‐cigarette flavour use (sweet, tobacco, menthol/mint) in interventional studies of e‐cigarettes for stopping smoking, and to estimate associations between flavours and smoking/vaping outcomes. Methods Update of secondary data analyses, including meta‐analyses subgrouped by flavour provision and narrative ...
Nicola Lindson, Jonathan Livingstone‐Banks, Ailsa R. Butler, David T. Levy, Phoebe Barnett, Annika Theodoulou, Caitlin Notley, Nancy A. Rigotti, Yixian Chen, Jamie Hartmann‐Boyce   +9 more
wiley   +1 more source

The Functional Topology of Phenylpiperazinium Agonists and Antagonists on the Nicotinic Acetylcholine Receptor Landscape: Pointing the Way for Future Therapeutic Management of Inflammation and Neuropathic Pain. [PDF]

ACS Chem Neurosci
Andleeb H, Gulsevin A, Papke RL.
europepmc   +1 more source

Activation and modulation of human α4β2 nicotinic acetylcholine receptors by the neonicotinoids clothianidin and imidacloprid

Journal of Neuroscience Research, 2011
Ping Li, Jason Ann, G. Akk
semanticscholar   +1 more source