Results 101 to 110 of about 611,342 (249)
РОЛЬ БЕЛКОВ NOTCH В ПРОЦЕССАХ КАНЦЕРОГЕНЕЗА [PDF]
, 2015 Notch transmembrane receptors family in humans consists of 4 proteins (Notch1–4) which are activated upon direct contact of cells, carrying appropriate ligands of Jagged or Dll families.
N. V. Khromova +9 more
core +1 more source
Redox‐Confined Interfacial Polymerization Enables Mechanically Robust and Self‐Adhesive Nanofilms
Advanced Materials Interfaces, EarlyView.Redox‐confined polymerization of a simple thiol monomer at a water‐organic interface generates robust freestanding films with nanoscale thickness. The resulting disulfide‐crosslinked nanofilms combine high stiffness with intrinsic adhesion to soft substrates, enabling conformal contact with artificial skin without additional functionalization.
Luana Gazzato +4 more
wiley +1 more source
NOTCH1, NOTCH3, NOTCH4, and JAG2 protein levels in human endometrial cancer
Medicina, 2014 Background and objective: Notch signaling is a conserved developmental pathway, which plays an important role in the regulation of cell proliferation, differentiation and death.
Aušra Sasnauskienė +7 more
doaj +1 more source
Determining the role of a small GTPase, Ral, and an endocytic factor, epsin, in Drosophila Notch signaling [PDF]
, 2013 textCell-cell communication events are crucial to determine the fate of each cell during development. Notch signaling is involved in many different contexts in determining cell fate by mediating cell-cell communication.
Cho, Bomsoo
core
Spheroid‐On‐A‐Drop: A Modular Droplet Microfluidics Platform
Advanced Materials Technologies, EarlyView.The proposed Spheroid‐on‐a‐Drop platform represents a reproducible and tunable platform for the fabrication of biocompatible GelMA‐based microgels, able to support controlled 3D tumor spheroid culture. Its precise control over droplet dynamics and cell distribution paves the way for advanced applications in tissue modeling, drug screening, and ...
A. Fergola +8 more
wiley +1 more source
eLife, 2018 The correct establishment and maintenance of unidirectional Notch signaling are critical for the homeostasis of various stem cell lineages. However, the molecular mechanisms that prevent cell-autonomous ectopic Notch signaling activation and deleterious ...
Bo Li +6 more
doaj +1 more source
Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties
Advanced Science, EarlyView.Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez +16 more
wiley +1 more source
Advanced Science, EarlyView.NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider +14 more
wiley +1 more source
An investigation into how the cell cycle and the Notch signalling pathway regulate pronephrogenesis in Xenopus laevis [PDF]
The connections between cell cycle exit and terminal differentiation remain poorly understood. Cyclin dependent Kinase Inhibitors (CKIs) provide a possible link between entry into the quiescent state and differentiation.
Naylor, Richard William
core
Charting Endocrine Progenitors Across Species and Organs
Advanced Science, EarlyView.Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing +21 more
wiley +1 more source