Results 111 to 120 of about 2,850,125 (303)

NOTCH1, NOTCH3, NOTCH4, and JAG2 protein levels in human endometrial cancer

Medicina, 2014
Background and objective: Notch signaling is a conserved developmental pathway, which plays an important role in the regulation of cell proliferation, differentiation and death.
Aušra Sasnauskienė, Violeta Jonušienė, Aurelija Krikštaponienė, Stasė Butkytė, Daiva Dabkevičienė, Daiva Kanopienė, Birutė Kazbarienė, Janina Didžiapetrienė   +7 more
doaj   +1 more source

Programmable 3D Photovoltaics via Mechanically Origami‐Coded Interlocked 3D Kirigami and Nano‐Root Anchored AgNWs–In–Ga Multiphasic Alloy Conductor

Advanced Materials, EarlyView.
Mechanically origami‐coded 3D kirigami photovoltaics convert a single extension–release cycle into deterministic self‐folding, reconfiguring planar solar cells into programmable 3D modules. Distinct coding strategies enable either ultrahigh stretchability (500% system strain) or ultrahigh initial effective areal coverage (225%).
Seok Joon Hwang, Jiwon Ryu, Byungsoo Kang, Injong Oh, Dae‐Hee Cho, YoungHoi Cho, Seung S. Lee, Dong Hoe Kim, Deokjae Choi, Gee Yeong Kim, Heesuk Jung, Taehee Kim, Hyeonggeun Yu, Seungjun Chung, Byoung Koun Min, Phillip Lee   +15 more
wiley   +1 more source

The retromer complex safeguards against neural progenitor-derived tumorigenesis by regulating Notch receptor trafficking

eLife, 2018
The correct establishment and maintenance of unidirectional Notch signaling are critical for the homeostasis of various stem cell lineages. However, the molecular mechanisms that prevent cell-autonomous ectopic Notch signaling activation and deleterious ...
Bo Li, Chouin Wong, Shihong Max Gao, Rulan Zhang, Rongbo Sun, Yulong Li, Yan Song   +6 more
doaj   +1 more source

Leaf‐Inspired Eutectic Skin With Extreme Fatigue Resistance and Robust Wet Adhesion for Amphibious Epidermal Electronics

Advanced Materials, EarlyView.
Inspired by Acorus calamus leaves, a heterogeneous eutectic skin integrates an aligned fibrous network within a hydrophobic eutectogel matrix. This hierarchical architecture triggers strain‐induced crystallization to achieve exceptional mechanical toughness and durable wet adhesion.
Jiayu Hou, Jiancheng Dong, Je Hyeong Kim, Chang Zhou, Shiyin Lin, Xingyu Liu, Hao Qiu, Mengting Zheng, Yuduo Zhang, Haijun Zhu, Kangjia Geng, Yidong Peng, Haoran Liu, Yunpeng Huang, Yongsheng Luo, Steve Park, Tianxi Liu   +16 more
wiley   +1 more source

Controlling Film Formation in Inkjet‐printed MAPbBr3 Through Graphene Incorporation for Enhanced Photodetection

Advanced Materials Technologies, EarlyView.
This work highlights the impact of incorporating graphene nanoflakes into precursor inks of MAPbBr3 for inkjet‐printed optoelectronic device applications. A substantial modification of the crystallization dynamics is reported despite miniscule concentrations.
Kenneth Lobo, Javier Bartolomé, María Vila, Giovanni Vescio, Raúl I. Sánchez‐Alarcón, Junaid Khan, Júlia Marí Guaita, Francisco Palacio Bonet, Juan P. Martínez‐Pastor, Sergi Hernández, Blas Garrido, Carmen Coya, Albert Cirera   +12 more
wiley   +1 more source

YB-1 Acts as a Ligand for Notch-3 Receptors and Modulates Receptor Activation*

Journal of Biological Chemistry, 2009
Y-box (YB) protein-1 is secreted by mesangial and immune cells after cytokine challenge, but extracellular functions are unknown. Here, we demonstrate that extracellular YB-1 associates with outer cell membrane components and interacts with extracellular
T. Rauen, U. Raffetseder, B. Frye, S. Djudjaj, Philipp J T Mühlenberg, F. Eitner, U. Lendahl, J. Bernhagen, S. Dooley, P. Mertens   +9 more
semanticscholar   +1 more source

ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

Advanced Science, EarlyView.
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao, Shannon Erhardt, Li Tang, Xiaotong Chen, Stephen M Farmer, Zixiu Cheng, Wen Chen, Ella Ziyuan Lu, Kihan Sung, Chang‐Ru Tsai, Mingjie Zheng, Sheng Zhang, Yang Liu, Jianxin Wang, Min Li, James F Martin, Jun Wang   +16 more
wiley   +1 more source

Notch Signaling in Neuroendocrine Tumors

Frontiers in Oncology, 2016
Carcinoids and neuroendocrine tumors (NETs) are a heterogeneous group of tumors that arise from the neuroendocrine cells of the GI tract, endocrine pancreas and the respiratory system.
Judy Sue Crabtree, Judy Sue Crabtree, Ciera eSingleton, Lucio eMiele, Lucio eMiele   +4 more
doaj   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

A model of Notch signalling control of angiogenesis: Evidence of a role for Notch ligand heterodimerization.

PLoS Computational Biology
The ubiquitous Notch receptor signalling network is essential for tissue growth and maintenance. Operationally, receptor activity is regulated by two principal, counterposed mechanisms: intercellular Notch transactivation triggered by interactions ...
Daipeng Chen, Xinxin Liu, Haijiang Wang, Roeland M H Merks, David A Baker   +4 more
doaj   +1 more source