Results 271 to 280 of about 2,850,125 (303)

[Signalling by Notch family receptors].

Comptes rendus des seances de la Societe de biologie et de ses filiales, 1997
From nematode to man, the transmembrane receptors of the Notch family act throughout embryonic and post-embryonic development to regulate the acquisition and/or maintenance of specific differentiative states. We will review here our current state of knowledge on Notch receptors structure and signalling activity.
F, Schweisguth, M, Gho, M, Lecourtois, V, Morel   +3 more
openaire   +1 more source

Evolution of Notch Transmembrane Receptors

2010
Notch is the transmembrane receptor of a juxtacrine signalling pathway (Notch pathway) crucial for cell programming during animal development. The active Notch pathway is an innovation of the metazoan lineage: several major components of this molecular network are absent from other eukaryotes. The transmembrane multidomain protein Notch emerged through
Eve, Gazave, Renard, Emmanuelle
openaire   +1 more source

Notch in Pericytes: Receptor Function and Targets

2020
Angiogenesis is the process by which pre-existing blood vessels sprout to from new ones. Mural cell recruitment to the capillary endothelium is essential for the stabilization of a newly forming vascular bed during angiogenesis and is tightly regulated. Notch signaling is a pathway that regulates vessel function and pericyte recruitment.
openaire   +1 more source

[Role of the Notch receptors in intercellular communication].

Pathologie-biologie, 1996
The Notch gene was discovered in Drosophila at the beginning of the century and is currently the subject of intensive investigation, not only in invertebrates but also in vertebrates where remarkably well conserved homologues have been recently found. Notch encodes a new kind of cellular receptor whose functioning is still unclear and plays a role in a
L, Seugnet, P, Simpson
openaire   +1 more source

Notch receptors as marker of glioma grading

2011
Gliomas are the most common neoplasms of the Central Nervous System (CNS) and a frequent cause of mental impairment and death. Gliomas are grouped into four clinical World Health Organization (WHO) grades according to their degree of malignancy.
Dell'Albani P, Pellitteri R, Rodolico M, Platania N, Albanese V, Aronica E, Catania MV   +6 more
openaire   +3 more sources

Alagille syndrome—a notch up for the Notch receptor

Nature Genetics, 1997
openaire   +1 more source

Kick it up a notch: Notch signaling and kidney fibrosis

Kidney International Supplements, 2014
Jianling Tao, Katalin Suszták
exaly  

The Varied Roles of Notch in Cancer

Annual Review of Pathology: Mechanisms of Disease, 2017
Jon C Aster, Warren S Pear, Stephen C Blacklow   +2 more
exaly  

REGULATION OF LYMPHOID DEVELOPMENT, DIFFERENTIATION, AND FUNCTION BY THE NOTCH PATHWAY

Annual Review of Immunology, 2005
Ivan Maillard, Warren S Pear
exaly  

Notch Signaling in the Tumor Microenvironment

Cancer Cell, 2018
Patrick Mehlen
exaly