Results 281 to 290 of about 2,850,125 (303)

Targeting Notch in oncology: the path forward

Nature Reviews Drug Discovery, 2020
Samarpan Majumder, Judy S Crabtree, Todd E Golde   +2 more
exaly  

Dynamic Ligand Discrimination in the Notch Signaling Pathway

Cell, 2018
Nagarajan Nandagopal, Leah A Santat, Lauren Lebon   +2 more
exaly  

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

Nature, 1998
E. Schroeter, Jeffrey A. Kisslinger, Raphael Kopan   +2 more
semanticscholar   +1 more source

A Tumor Suppressor Function for Notch Signaling in Forebrain Tumor Subtypes

Cancer Cell, 2015
Robert Ivanek, Alvaro Alvarado, Luigi Mariani   +2 more
exaly  

Epsin-Dependent Ligand Endocytosis Activates Notch by Force

Cell, 2017
Paul D Langridge, Gary Struhl
exaly  

Modulation of Phase Shift between Wnt and Notch Signaling Oscillations Controls Mesoderm Segmentation

Cell, 2018
Katharina F Sonnen, Volker M Lauschke, Henning J Falk   +2 more
exaly  

MAML1, a human homologue of Drosophila Mastermind, is a transcriptional co-activator for NOTCH receptors

Nature Genetics, 2000
Lizi Wu, J. Aster, S. Blacklow, R. Lake, S. Artavanis-Tsakonas, J. Griffin   +5 more
semanticscholar   +1 more source

REGULATION OF T CELL FATE BY NOTCH

Annual Review of Immunology, 1999
Ellen A Robey
exaly  

Notch receptor processing and CNS disease

2002
We have studied the relationship of Notch receptor processing and two diseases of the central nervous system: Alzheimer's disease (AD) and Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL). The Notch receptor signalling pathway plays a crucial role during development in many different species for ...
openaire   +1 more source

Therapeutic modulation of Notch signalling — are we there yet?

Nature Reviews Drug Discovery, 2014
Emma R Andersson, Urban Lendahl, Andersson Emma R   +2 more
exaly