Results 121 to 130 of about 83,214 (263)

Effect of Dezocine and Dexmedetomidine as Adjuvants in Ropivacaine for Incision Subcutaneous Infiltration Anesthesia on Incision Healing in Diabetic Rats

open access: yesBrain and Behavior, Volume 15, Issue 12, December 2025.
The adjunctive use of dezocine and dexmedetomidine with ropivacaine in incisional subcutaneous infiltration anesthesia may contribute to improved incision healing in diabetic rats. ABSTRACT Introduction Surgery can induce insulin resistance (IR) in diabetic patients, and severe IR compromises the body's ability to combat infection and shock, impairs ...
Lang Yu   +7 more
wiley   +1 more source

Phylogenomic analysis reveals extensive phylogenetic mosaicism in the Human GPCR Superfamily [PDF]

open access: yes, 2007
A novel high throughput phylogenomic analysis (HTP) was applied to the rhodopsin G-protein coupled receptor (GPCR) family. Instances of phylogenetic mosaicism between receptors were found to be frequent, often as instances of correlated mosaicism and ...
Allaby, Robin G., Woodwark, Mathew
core   +2 more sources

UPLC–ESI–QToF–MS Profile of Hydroalcoholic Extract of Persea cordata (Meisn.) and its Antioedematogenic and Antinociceptive Effects in Mice

open access: yesChemistry &Biodiversity, Volume 22, Issue 12, December 2025.
Hydroalcoholic crude extract of Persea cordata showed in its composition, the presence of lignans based on LCESIMS data. This crude extract displayed anti‐oedematogenic and antinociceptive activities in vivo. Abstract This study aimed to establish the chemical profile and evaluate the anti‐oedematogenic and analgesic activities of the hydroalcoholic ...
Valfredo Schlemper   +6 more
wiley   +1 more source

Behavioral meaningful opioidergic stimulation activates kappa receptor gene expression

open access: yesBrazilian Journal of Medical and Biological Research, 2012
The periaqueductal gray (PAG) has been reported to be a location for opioid regulation of pain and a potential site for behavioral selection in females.
E. Teodorov   +4 more
doaj   +2 more sources

On the G-protein-coupled receptor heteromers and their allosteric receptor-receptor interactions in the central nervous system: focus on their role in pain modulation [PDF]

open access: yes, 2013
The modulatory role of allosteric receptor-receptor interactions in the pain pathways of the Central Nervous System and the peripheral nociceptors has become of increasing interest.
Agnati, Luigi F   +6 more
core   +3 more sources

Worldwide Research Trends on Substance Use Disorder‐Related Inflammatory Imbalances: A Bibliometric Analysis

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
A bibliometric analysis of worldwide research trends on “substance use disorder‐related inflammation”. “Neuroinflammation” is identified as a key research hotspot. The findings provide a data‐driven overview of the evolving landscape in this field. ABSTRACT Background Substance use disorder (SUD) is a complex, chronic, and relapsing encephalopathy ...
Shirui Cao   +3 more
wiley   +1 more source

Expression of adrenergic, acetylcholine and kappa opioid receptors on peripheral blood lymphocytes in patients with herpetic keratitis and those with idiopathic anterior and/or intermediate uveitis

open access: yesJournal of Ophthalmology
Purpose: To assess the expression of adrenergic, acetylcholine (ACh) and opioid receptors on peripheral blood lymphocytes in patients with herpetic keratitis (HK) and those with idiopathic anterior and/or intermediate uveitis (IAIU). Methods: Thirty one
L. M. Velychko   +5 more
doaj   +1 more source

Response of striosomal opioid signaling to dopamine depletion in 6-hydroxydopamine-lesioned rat model of Parkinson’s disease: a potential compensatory role.

open access: yesFrontiers in Cellular Neuroscience, 2013
The opioid peptide receptors consist of three major subclasses, namely, mu, delta and kappa (MOR, DOR and KOR, respectively). They are involved in the regulation of striatal dopamine functions, and increased opioid transmissions are thought to play a ...
Hidetaka eKoizumi   +6 more
doaj   +1 more source

Opioid receptors signaling network

open access: yesJournal of cell communication and signaling, 2021
Lathika Gopalakrishnan   +6 more
semanticscholar   +1 more source

Adverse Effects of Opioid Dependency on Central and Peripheral Aspects of the Neuromuscular System

open access: yes, 2019
Prevalence of chronic pain and health care costs have caused an escalation of opioid dependency. The current national crisis involving opioid dependency and drug overdose are growing problems that need to be addressed.
Yang, Cindy
core  

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