Results 141 to 150 of about 2,452,900 (288)

Regulation of µ-Opioid Receptors: Desensitization, Phosphorylation, Internalization, and Tolerance

Pharmacological Reviews, 2013
John T. Williams, S. Ingram, G. Henderson, C. Chavkin, M. von Zastrow, S. Schulz, T. Koch, C. Evans, M. Christie   +8 more
semanticscholar   +1 more source

Opioids and Their Receptors [PDF]

, 2003
openaire   +2 more sources

Negative impact of corticosteroid use on outcome in patients with advanced BTCs treated with cisplatin, gemcitabine, and durvalumab: A large real‐life worldwide population

International Journal of Cancer, EarlyView.
What's new? In recent years, the possible prognostic impact of concomitant medications in patients with cancer treated with immunotherapy combinations has generated increasing interest. This real‐world analysis evaluated the impact of concomitant medications on survival outcomes in patients with advanced biliary tract cancer treated with cisplatin ...
Federica Lo Prinzi, Francesca Salani, Silvia Camera, Mario Domenico Rizzato, Anna Saborowski, Lorenzo Antonuzzo, Federico Rossari, Tomoyuki Satake, Frederik Peeters, Tiziana Pressiani, Jessica Lucchetti, Jin Won Kim, Oluseyi Abidoye, Ilario Giovanni Rapposelli, Chiara Gallio, Stefano Tamberi, Fabian Finkelmeier, Guido Giordano, Pircher Chiara, Hong Jae Chon, Chiara Braconi, Aitzaz Qaisar, Alessandro Pastorino, Florian Castet, Emiliano Tamburini, Changhoon Yoo, Alessandro Parisi, Anna Diana, Mario Scartozzi, Gerald W. Prager, Antonio Avallone, Marta Schirripa, Il Hwan Kim, Lukas Perkhofer, Ester Oneda, Monica Verrico, Nuno Couto, Jorge Adeva, Stephen L. Chan, Gian Paolo Spinelli, Nicola Personeni, Ingrid Garajova, Maria Grazia Rodriquenz, Silvana Leo, Cecilia Melo Alvim, Ricardo Roque, Mariam Grazia Polito, Emanuela Di Giacomo, Giovanni Farinea, Linda Bartalini, Giada Grelli, Antonio De Rosa, Daniele Lavacchi, Masafumi Ikeda, Jeroen Dekervel, Monica Niger, Rita Balsano, Giuseppe Tonini, Minsu Kang, Giulia Tesini, Alessandra Boccaccino, Vera Himmelsbach, Matteo Landriscina, Selma Ahcene Djaballah, Tanios Bekaii‐Saab, Lorenzo Fornaro, Gianluca Masi, Arndt Vogel, Sara Lonardi, Margherita Rimini, Lorenza Rimassa, Andrea Casadei‐Gardini   +71 more
wiley   +1 more source

Investigating Endogenous Opioids Unravels the Mechanisms Behind Opioid-Induced Constipation, a Mathematical Modeling Approach. [PDF]

Int J Mol Sci
Coomber C, Chewle S, Secker C, Fackeldey K, Weber M, Winkelmann S, Schütte C, Sunkara V.   +7 more
europepmc   +1 more source

5‐HT3 receptor antagonists for preventing postoperative nausea and vomiting after gynecological surgery: A systematic review and network meta‐analysis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Gynecological surgery is generally associated with a high risk of postoperative nausea and vomiting (PONV), for which a combination of antiemetic therapies is advised, but adherence to these protocols is often low. Given the current reality, a preferred 5‐HT3 receptor antagonist for preventing PONV as a result of gynecological ...
Hongxia Xu, Lingyan Rong, Shaohui Yang, Jiankun Xing, Huajun Dong, Huihui Liu, Xiaotao Chen, Lingyan Liu   +7 more
wiley   +1 more source

Selective targeting of mu opioid receptors to primary cilia

Cell Reports
Summary: Opioid receptors are therapeutically important G protein-coupled receptors (GPCRs) with diverse neuromodulatory effects. The functional consequences of opioid receptor activation are known to depend on receptor location in the plasma membrane ...
Rita R. Fagan, David F. Lee, Matan Geron, Grégory Scherrer, Mark von Zastrow, Aliza T. Ehrlich   +5 more
doaj  

Molecular and cellular basis of mu-opioid receptor signaling: mechanisms underlying tolerance and dependence development. [PDF]

Front Neurosci
Swingler M, Donadoni M, Unterwald EM, Maggirwar SB, Sariyer IK.   +4 more
europepmc   +1 more source

Effects of integrated programs for substance‐involved mothers on infant and child development outcomes: A systematic review and meta‐analysis

Infant Mental Health Journal: Infancy and Early Childhood, EarlyView.
Abstract Maternal substance use is a pressing public health issue that confers risk for maternal health, the parent‐infant relationship, and child development. Integrated interventions that jointly address maternal substance use and child development have shown promise for enhancing child outcomes.
Sophie Barriault, Mary Motz, Lamia Firasta, Hannah McDowell, Patrick R. Labelle, Nancy Poole, Nicole Racine   +6 more
wiley   +1 more source

Acute Postural Effects of Spinal Cord Injury: Dual Neural Opioid and Endocrine Non-Opioid Mechanism. [PDF]

Cells
Watanabe H, Lavrov I, Hallberg M, Schouenborg J, Zhang M, Bakalkin G.   +5 more
europepmc   +1 more source

A Study on the Addictive Feature of Nonsuicidal Self‐Injury in Adolescents With Depression Disorders and Its Correlation With Serum Beta‐Endorphin Concentration and Neural Reward Responsiveness

iRADIOLOGY, EarlyView.
NSSI is addictive in adolescents with depression disorders. It may be related to the decrease of serum beta‐endorphin concentration and the activation of brain reward system. ABSTRACT Background Nonsuicidal self‐injury (NSSI) in adolescents with depression disorders often exhibits addictive patterns, potentially linked to serum beta‐endorphin levels ...
Jie Li, Xiaogang Zhu, Peiwen Zhang, Yuxing Wang, Jian Zhong, Yiming Wang, Lixia Yang   +6 more
wiley   +1 more source